Results 111 to 120 of about 15,724 (296)
P-selectin mediates metastatic progression through binding to sulfatides on tumor cells [PDF]
, 2017 Hematogenous carcinoma metastasis is associated with tumor cell emboli formation, which is now known to be facilitated by selectins. P-selectin-mediated interactions of platelets with cancer cells are based mostly on mucin- and glycosaminoglycan-type ...
Borsig, L., Callewaert, N., Garcia, J.
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Journal of Chemistry, Volume 2025, Issue 1, 2025.The formation of biofilms occurs due to a group of bacteria gathering together. The increasing of cell density will stimulate chemical signals for bacteria to communicate through quorum sensing system. Quorum sensing plays a role for competition, virulence, resistance, and pathogenesis. Quorum sensing produces signaling response called as autoinducers.
Salsabila Aqila Putri +4 more
wiley +1 more source
Journal of Neuroscience, 2014 Enzyme replacement therapy (ERT) is a treatment option for lysosomal storage disorders (LSDs) caused by deficiencies of soluble lysosomal enzymes. ERT depends on receptor-mediated transport of intravenously injected recombinant enzyme to lysosomes of ...
Annika Böckenhoff +7 more
semanticscholar +1 more source
Mammalian sulfo-conjugate metabolism [PDF]
, 1987 Sulfoconjugates occur ubiquitously as sulfopolysaccharides, sulfolipids and sulfoproteins. A variety of sulfotransferases catalyze the sulfation process with 3'- phosphoadenosine 5'-phosphosulfate as the sulfate donor.
Balasubramanian, A. S., Mathew, Joy
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Enhancing the Steroid Sulfatase Activity of the Arylsulfatase from Pseudomonas aeruginosa [PDF]
, 2018 Steroidal sulfate esters play a central role in many physiological processes. They serve as the reservoir for endogenous sex hormones and form a significant fraction of the steroid metabolite pool.
Kamerlin, Shina C. L. +4 more
core +3 more sources
Hair follicle sulfotransferase activity and effectiveness of oral minoxidil in androgenetic alopecia
Journal of Cosmetic Dermatology, Volume 23, Issue 11, Page 3767-3773, November 2024.Abstract Background Androgenetic alopecia (AGA) is common. While topical minoxidil remains the only FDA‐approved therapeutic for AGA, its efficacy is limited in stimulating clinically significant hair regrowth over the longer term. Oral minoxidil, which is used off‐label, is a promising alternative; however, its effectiveness and underlying mechanisms ...
Juan Jimenez‐Cauhe +14 more
wiley +1 more source
Transition-State Interactions in a Promiscuous Enzyme: Sulfate and Phosphate Monoester Hydrolysis by Pseudomonas aeruginosa Arylsulfatase. [PDF]
, 2019 Pseudomonas aeruginosa arylsulfatase (PAS) hydrolyzes sulfate and, promiscuously, phosphate monoesters. Enzyme-catalyzed sulfate transfer is crucial to a wide variety of biological processes, but detailed studies of the mechanistic contributions to its ...
Berry, Ryan +6 more
core +3 more sources
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 195, Issue 7, October 2024.Abstract Hereditary spastic paraplegia (HSP) is a group of familial diseases characterized by progressive corticospinal tract degeneration. Clinically, patients present with lower‐limb spasticity and weakness. To date, more than 80 genetic HSP types have been identified.
Woong‐Woo Lee +2 more
wiley +1 more source
Separation and analysis of arylsulfatase isoenzymes in body fluids of man. [PDF]
, 1978 W.D. Bostick +3 more
openalex +2 more sources
Chromogranins, widespread in endocrine and nervous tissue, bind Ca2+ [PDF]
, 1985 The proteinaceous components of the secretory vesicle contents isolated from bovine adrenal medulla bind Ca2+ (number of binding sites, 152 ± 52 nmol Ca2+ per mg protein; dissociation constant, 54 ± 8 μM (n = 5)).
Gratzl, Manfred, Reiffen, F. U.
core +1 more source