Биопрепараты: Профилактика, диагностика, лечение, 2022 Maroteaux—Lamy syndrome (mucopolysaccharidosis type VI) is an orphan genetic disease caused by mutations in the arylsulfatase B gene (ARSB), which encodes the lysosomal enzyme arylsulfatase B (ASB).
S. S. Timonova +7 more
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Arylsulfatase A pseudodeficiency in healthy Brazilian individuals [PDF]
Brazilian Journal of Medical and Biological Research, 1999 Molecular alterations associated with arylsulfatase A pseudodeficiency (ASA-PD) were characterized by PCR and restriction endonuclease analysis in a sample of healthy individuals from Brazil. ASA activity was also assayed in all subjects. Two individuals
C.G. Pedron +3 more
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Structural insights into manganese-dependent arylsulfatase from Enterococcus faecium and its catalytic promiscuity [PDF]
mBioCatalytic promiscuity, wherein enzymes catalyze multiple distinct reactions by stabilizing various transition states, is well documented in the alkaline phosphatase superfamily.
Lulu Guo +9 more
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Arylsulfatase A deficiency causes seminolipid accumulation and a lysosomal storage disorder in Sertoli cells[S] [PDF]
Journal of Lipid Research, 2011 Sulfogalactosylglycerolipid (SGG) is the major sulfoglycolipid of male germ cells. During spermatogenesis, apoptosis occurs in >50% of total germ cells.
Hongbin Xu +8 more
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Nonclinical comparability studies of recombinant human arylsulfatase A addressing manufacturing process changes. [PDF]
PLoS ONE, 2018 Recombinant human arylsulfatase A (rhASA) is in clinical development for the treatment of patients with metachromatic leukodystrophy (MLD). Manufacturing process changes were introduced to improve robustness and efficiency, resulting in higher levels of ...
Teresa Wright +6 more
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Arylsulfatase K attenuates airway epithelial cell senescence in COPD by regulating parkin-mediated mitophagy [PDF]
Redox BiologyChronic obstructive pulmonary disease (COPD) is a heterogeneous lung condition characterized by irreversible airflow limitation, primarily due to cigarette smoke (CS) exposure.
Ruonan Yang +12 more
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Arylsulfatase A pseudodeficiency incidence in Turkey
The Turkish Journal of Pediatrics, 2000 Pseudodeficiency (Pd) in arylsulfatase A (ASA) is a relatively frequent condition in healthy individuals. It produces a reduction in enzyme activity similar to that found in metachromatic leukodystrophy (MLD). A variable incidence of the Pd allele
S Emre, M Topçu, M Terzioğlu, Y Renda
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Interactions of CFTR and Arylsulfatase B (ARSB; N-acetylgalactosamine-4-sulfatase) in Prostate Carcinoma. [PDF]
Int J Mol SciBhattacharyya S, Tobacman JK.
europepmc +3 more sources
Specific Fertilization Practices Reveal Important Insights into the Complex Interaction Between Microbes and Enzymes in Soils of Different Farming Systems [PDF]
LifeThe interaction of microorganisms and their enzyme activity is one of the key indicators for a comprehensive measurement of soil health. The aim of this study was to determine significant correlations between different soil microorganisms and enzyme ...
Maša Pintarič +3 more
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