Results 141 to 150 of about 6,281 (181)

Pseudodeficiency of arylsulfatase A: a counseling dilemma

Clinical Genetics, 1987
Arylsulfatase A (ASA) deficiency is the cause of early and late onset metachromatic leukodystrophy (MLD). Low ASA levels are detected in some healthy individuals who are pseudodefi‐cient (PD). PD individuals can be distinguished, because PD fibroblasts hydrolyze14C‐sulfatide at similar rates to normal fibroblasts.
S, Baldinger, M E, Pierpont, D A, Wenger
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A new electrophoretic variant of arylsulfatase A

Biochemical Medicine and Metabolic Biology, 1988
Previous work in this laboratory has identified electrophoretic variant forms of arylsulfatase A in leucocyte plus platelets. During a study to replicate and extend these findings, a new seven-band variant of arylsulfatase A has been identified. Purified platelets gave a clearer, more distinct electrophoretic banding pattern than the leucocyte and ...
P, Manowitz, L V, Fine, R, Nora, S, Chokroverty, P E, Nathan, J M, Fazzaro   +5 more
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Pseudodeficiencies of Arylsulfatase A and Galactocerebrosidase Activities

Developmental Neuroscience, 1991
Pseudodeficiency is defined as the in vitro measurement of low activity (usually under 15% of the normal mean for controls) of an enzyme in a healthy person. They may be hard to distinguish from presymptomatic people who will present with adult-onset clinical disease.
D A, Wenger, E, Louie
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Arylsulfatase A Pseudodeficiency - Incidence in Poland

European Journal of Human Genetics, 1996
Arylsulfatase A (ASA) pseudodeficiency (Pd) was defined as the in vitro measurement of low enzyme activity in a healthy person. A variable incidence of the Pd allele was found in different populations; it was 10-20 times higher than that of metachromatic leukodystrophy (MLD).
B, Czartoryska, J G, Zimowski, M, Bisko, D, Górska   +3 more
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A simple chromogenic assay for arylsulfatase A

Clinica Chimica Acta, 1987
Arylsulfatase A hydrolyzes the artificial chromogenic substrate 4-nitrocatechol-sulfate at 0 degree C at a rate of 24% of that at 37 degrees C whereas arylsulfatase B is almost inactive at 0 degree C. Based on this observation, a simple assay was developed which permits the accurate determination of low residual arylsulfatase A activities in cultured ...
M, Lee-Vaupel, E, Conzelmann
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Arylsulfatase A Variants in Patients with Alcoholism

Alcoholism: Clinical and Experimental Research, 1984
Leukocytes from 200 mentally ill patients and 100 normal controls were analyzed for eiectrophoretic variants of arylsulfatase A. Four different variant forms were found in 15 subjects. There is a relatively high occurrence of the arylsulfatase A variants in patients with alcoholism. Twenty‐one per cent (12/56) of patients with alcoholism have a variant
A R, Hulyalkar, R, Nora, P, Manowitz
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Arylsulfatases of human tissue studies on a form of arylsulfatase B found predominantly in brain

Biochimica et Biophysica Acta (BBA) - Enzymology, 1977
The distribution of soluble arylsulfatase (aryl-sulfate sulfohydrolases, EC 3.1.6.1) in human tissues was investigated by DEAE-cellulose chromatography, All tissues examined contained arylsulfatase A and arylsulfatase B. In addition, brain singularly contained significant quantities (15-25% of total arylsulfatase) of a minor anionic arylsulfatase from ...
R L, Stevens, A L, Fluharty, A R, Killgrove, Y, Kihara   +3 more
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Arylsulfatase in coelomocytes ofHolothuria polii

Experientia, 1988
Holothuria polii coelomocytes possess arylsulfatase enzymes. Two pH optima were found for arylsulfatase activity in cell lysate preparations, one at pH 5.0 and the other at pH 5.8. Both increased after injection of zymosan particles or formalinized sheep red blood cells (fSR-BC), indicating an active role of the enzymes during phagocytosis of ...
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Arylsulfatases in bilharziasis.

Egyptian journal of bilharziasis, 1978
Arylsulfatase A and B in urine have been estimated in 18 normal subjects and 50 bilharziasis patients. The bilharziasis patients were divided into two groups according to the type of infeciton. Those with bilharziasis haematobian type of infection and those with the bilharziasis mansoni type.
E Z, Khafagy, H E, Raziky, A F, Galal
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Mammalian arylsulfatase

Archives of Biochemistry and Biophysics, 1954
G D, MAENGWYN-DAVIES, J S, FRIEDENWALD
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