Results 31 to 40 of about 7,425 (206)

Simultaneous determination of minoxidil and minoxidil sulfate by high-performance liquid chromatography with UV-detection and its applications

Medicine in Drug Discovery, 2020
Aims: Minoxidil is a hair growth drug for treating androgenetic alopecia. Although minoxidil is generally administered as a topical formulation, this prodrug must be converted to its active form (minoxidil sulfate) by sulfotransferase in hair follicle ...
Mio Ichida, Chiharu Fujita, Rena Sumie, Ryotaro Miyano, Hajime Inoue   +4 more
doaj   +1 more source

Soil enzymatic activity under coffee cultivation with different water regimes associated to liming and intercropped brachiaria

Ciência Rural, 2021
: This research evaluated the effects of coffee cultivation with two different water regimes associated or not with liming and the presence/absence of brachiaria as intercrop on the activities of the soil enzymes β-glucosidase, arylsulfatase and acid ...
Raquel Nogueira Rodrigues, Fábio Bueno dos Reis Junior, André Alves de Castro Lopes, Omar Cruz Rocha, Antônio Fernando Guerra, Adriano Delly Veiga, Ieda de Carvalho Mendes   +6 more
doaj   +1 more source

Retrovirally expressed human arylsulfatase A corrects the metabolic defect of arylsulfatase A-deficient mouse cells [PDF]

Gene Therapy, 2000
A deficiency of arylsulfatase A (ASA) causes the lysosomal storage disease metachromatic leukodystrophy (MLD) which is characterized primarily by demyelination of the central nervous system. ASA-deficient mice develop a disease which resembles MLD in many respects and thus serve as an appropriate animal model for this disease. To establish gene therapy
U, Matzner, M, Habetha, V, Gieselmann
openaire   +2 more sources

Identification of a novel mutation in ARSA gene in three patients of an Iranian family with metachromatic leukodystrophy disorder

Genetics and Molecular Biology, 2017
Metachromatic leukodystrophy disorder (MLD) is an autosomal recessive and lysosomal storage disease. The disease is caused by the deficiency of the enzyme arylsulfatase A (ARSA) which is encoded by the ARSA gene. Different mutations have been reported in
Neda Golchin, Mohammadreza Hajjari, Reza Azizi Malamiri, Majid Aminzadeh, Javad Mohammadi-asl   +4 more
doaj   +1 more source

Measurement of sulfatides in the amniotic fluid supernatant: A useful tool in the prenatal diagnosis of metachromatic leukodystrophy

JIMD Reports, 2022
Metachromatic leukodystrophy (MLD) is an autosomal recessive lysosomal disorder caused by deficiency of arylsulfatase A (ARSA), leading to an accumulation of sulfatides.
Francyne Kubaski, Zackary M. Herbst, Maira Graeff Burin, Kristiane Michelin‐Tirelli, Franciele B. Trapp, Rejane Gus, Alice B. O. Netto, Ana Carolina Brusius‐Facchin, Sandra Leistner‐Segal, Maria Teresa Sanseverino, Carolina Moura Fischinger de Souza, Matheus V. M. B. Wilke, Thiago Oliveira, Jose A. A. Magalhães, Roberto Giugliani   +14 more
doaj   +1 more source

A patient presenting a 22q13 deletion associated with an apparently balanced translocation t(16;22): an illustrative case in the investigation of patients with low ARSA activity

Genetics and Molecular Biology, 2012
A 10-year-old speechless, mentally deficient male, with low arylsulfatase A (ARSA) activity, and presumably, methachromatic leukodystrophy, underwent genetic evaluation.
Osvaldo Artigalás, Giorgio Paskulin, Mariluce Riegel, Maira Burin, Maria Luiza Saraiva-Pereira, Sharbel Maluf, Andrea Kiss, Ida Vanessa D. Schwartz   +7 more
doaj   +1 more source

Organic Matter Regulates Ammonia-Oxidizing Bacterial and Archaeal Communities in the Surface Sediments of Ctenopharyngodon idellus Aquaculture Ponds

Frontiers in Microbiology, 2018
Ammonia-oxidizing bacteria (AOB) and archaea (AOA) play important roles in nitrogen removal in aquaculture ponds, but their distribution and the environmental factors that drive their distribution are largely unknown.
Lili Dai, Lili Dai, Chengqing Liu, Chengqing Liu, Liqin Yu, Chaofeng Song, Liang Peng, Xiaoli Li, Ling Tao, Gu Li   +9 more
doaj   +1 more source

Soil enzymatic activity and wheat grain yield under cover crop systems

Pesquisa Agropecuária Tropical, 2023
For years, the impacts of using cover crops in productive systems have been measured by their relation with soil chemical and physical characteristics. Consequently, the effects on the soil microbiological characteristics have been little explored.
Luís Felipe Rossetto Gerlach, Antônio Luis Santi, Ezequiel Zibetti Fornari, Guilherme Rechden Lobato, Larrisa Lamperti Tonello   +4 more
doaj   +1 more source

Biochar and Sulphur Enriched Digestate: Utilization of Agriculture Associated Waste Products for Improved Soil Carbon and Nitrogen Content, Microbial Activity, and Plant Growth

Agronomy, 2021
A number of agriculture residues may be used either directly or after suitable treatment as amendments to improve soil quality. Such materials include biochar made of agriculture residues, digestate or elemental sulphur obtained from biogas ...
Tereza Hammerschmiedt, Jiri Holatko, Marek Sudoma, Antonin Kintl, Jan Vopravil, Pavel Ryant, Petr Skarpa, Maja Radziemska, Oldrich Latal, Martin Brtnicky   +9 more
doaj   +1 more source

Relative Frequency of Metachromatic Leukodystrophy in Egypt: A Reference Laboratory Report

Frontiers in Bioscience-Scholar
Background: Metachromatic leukodystrophy (MLD) is an autosomal recessive hereditary neurodegenerative disease caused by a deficiency in arylsulfatase A (ARSA) activity and belongs to the group of lysosomal storage diseases.
Ekram Fateen, Zeinab Y. Abdallah
doaj   +1 more source