Results 11 to 20 of about 30,414 (210)

Efficacy of Adjunct Olanzapine Treatment in Adolescents With Anorexia Nervosa: A Comparison of Two Patient Cohorts. [PDF]

Eur Eat Disord Rev
ABSTRACT Background Anorexia nervosa (AN) is a severe psychiatric disorder with high mortality, requiring innovative treatment strategies. Olanzapine (OLZ), an atypical antipsychotic, has demonstrated efficacy in promoting weight gain and reducing psychopathological symptoms in adults with AN.
Krauss H, Zeiler M, Mairhofer D, Klang J, Schwarzenberg J, Mitterer M, Wagner G, Glüder M, Egberts K, Gerlach M, Karwautz A.   +10 more
europepmc   +2 more sources

Breeding of Cav2.3 deficient mice reveals Mendelian inheritance in contrast to complex inheritance in Cav3.2 null mutant breeding

Scientific Reports, 2021
High voltage-activated Cav2.3 R-type Ca2+ channels and low voltage-activated Cav3.2 T-type Ca2+ channels were reported to be involved in numerous physiological and pathophysiological processes.
Anna Papazoglou, Christina Henseler, Karl Broich, Johanna Daubner, Marco Weiergräber   +4 more
doaj   +1 more source

Ein Markt ohne Zukunft [PDF]

, 2006
In den letzten Jahren wurden die Ausgaben der Gesetzlichen Krankenversicherung zunehmend durch hohe Arzneimittelkosten belastet. Wodurch wurde diese Entwicklung verursacht? Welche Reformen werden für den Arzneimittelmarkt diskutiert?
Münnich, Frank E.
core   +3 more sources

Effectiveness and safety of dexamphetamine sulfate (Attentin®) in the routine treatment of children and adolescents with ADHD: results from a 12-month non-interventional study

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, 2021
Randomized controlled trials have shown that dexamphetamine sulfate (DEX) is efficacious in the treatment of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents; however, data on the effectiveness and safety of DEX in routine ...
Uebel-von Sandersleben Henrik, Dangel Oliver, Fischer Roland, Ruhmann Michaela, Huss Michael   +4 more
doaj   +1 more source

Physiology-based IVIVE predictions of tramadol from in vitro metabolism data [PDF]

, 2014
To predict the tramadol in vivo pharmacokinetics in adults by using in vitro metabolism data and an in vitro-in vivo extrapolation (IVIVE)-linked physiologically-based pharmacokinetic (PBPK) modeling and simulation approach (SimcypA (R)).
Allegaert, Karel, Annaert, Pieter, Boussery, Koen, Colin, Pieter, Cuyckens, Filip, Mannens, Geert, Snoeys, Jan, T'jollyn, Huybrecht, Van Bocxlaer, Jan, Van Peer, Achiel, Vermeulen, An   +10 more
core   +1 more source

Impact of treatment planning target volumen (PTV) size on radiation induced diarrhoea following selenium supplementation in gynecologic radiation oncology - a subgroup analysis of a multicenter, phase III trial [PDF]

, 2013
Background: In a previous analysis (Int J Radiat Oncol Biol Phys 70:828-835,2010), we assessed whether an adjuvant supplementation with selenium (Se) improves Se status and reduces the radiation-induced side-effects of patients treated by adjuvant ...
Adamietz, Irenäus A., Baaske, Dieter, Berndt-Skorka, Regina, Buentzel, Jens, Eich, Hans-Theodor, Glatzel, Michael, Huebner, Jutta, Kisters, Klaus, Kundt, Guenther, Micke, Oliver, Muecke, Ralph, Prott, Franz-Josef, Reichl, Berthold, Schaefer, Ulrich, Schomburg, Lutz   +14 more
core   +1 more source

Regulatorische Anforderungen an die Produktion und Qualität pflanzlicher Arzneimittel

Julius-Kühn-Archiv, 2014
Entwicklung, Zulassung, Produktion sowie die Vermarktung und der Vertrieb von Arzneimitteln unterliegen in Europa harmonisierten Regularien, die im Gemeinschaftskodex für Humanarzneimittel (Richtlinie 2001/83/EG) zusammengefasst sind und auch pflanzliche
Hagels, Hansjörg, Tegtmeier, Martin, Strube, Jochen   +2 more
doaj   +1 more source

Enhanced hippocampal type II theta activity AND altered theta architecture in mice lacking the Cav3.2 T-type voltage-gated calcium channel

Scientific Reports, 2021
T-type Ca2+ channels are assumed to contribute to hippocampal theta oscillations. We used implantable video-EEG radiotelemetry and qPCR to unravel the role of Cav3.2 Ca2+ channels in hippocampal theta genesis.
Muhammad Imran Arshaad, Magdalena Elisabeth Siwek, Christina Henseler, Johanna Daubner, Dan Ehninger, Jürgen Hescheler, Agapios Sachinidis, Karl Broich, Anna Papazoglou, Marco Weiergräber   +9 more
doaj   +1 more source

Effect of a newly developed pastille on the salivary flow rate in subjects with dry mouth symptoms: a randomized, controlled, monocentric clinical study

BMC Oral Health, 2021
Background Xerostomia is associated with several diseases and is a side effect of certain drugs, resulting from reduced saliva secretion. Often, aged and sometimes younger people suffer from (idiopathic) xerostomia.
S. Bielfeldt, D. Wilhelm, C. Neumeister, U. Schwantes, K. -P. Wilhelm   +4 more
doaj   +1 more source

Pharmacokinetics of a Modified-Release Dexamphetamine Sulfate Formulation Following Single and Multiple Dosing in Healthy Adults: Comparative Bioavailability with Immediate-Release Dexamphetamine Sulfate, between Strengths, Assessment of Food and Meal Composition Effects

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, 2023
A modified-release dexamphetamine sulfate formulation (DEX-MR) is under development for the treatment of attention-deficit/hyperactivity disorder.
Sandersleben Henrik Uebel-von, Mayer Anke, Ruhmann Michaela, Dangel Oliver, Schütz Helmut   +4 more
doaj   +1 more source