Results 41 to 50 of about 4,126 (156)

The public health impact of malaria vaccine RTS,S in malaria endemic Africa: country-specific predictions using 18 month follow-up Phase III data and simulation models [PDF]

, 2015
The RTS,S/AS01 malaria vaccine candidate recently completed Phase III trials in 11 African sites. Recommendations for its deployment will partly depend on predictions of public health impact in endemic countries.
Katya Galactionova, Marcel Tanner, Michael Tarantino, Melissa A Penny, Smith, Thomas A., Galactionova, Katya, Tarantino, Michael, Thomas A Smith, Penny, Melissa A., Tanner, Marcel, Smith TA, Tarantino M, Tanner M, Penny MA, Galactionova K   +14 more
core   +1 more source

Cellular and molecular synergy in AS01-adjuvanted vaccines results in an early IFNγ response promoting vaccine immunogenicity [PDF]

, 2017
Combining immunostimulants in adjuvants can improve the quality of the immune response to vaccines. Here, we report a unique mechanism of molecular and cellular synergy between a TLR4 ligand, 3-O-desacyl-4’-monophosphoryl lipid A (MPL), and a saponin, QS-
Mary J. van Helden, Margherita Coccia, Didierlaurent, Arnaud M, Sheetij Dutta, Smilde, Age K., van der Most, R., Welsby, Iain, Smilde, A.K.; id_orcid, Garçon, Nathalie, Genito, Christopher J., Sandra Morel, van der Most, Robbert, Hervet, Caroline, Dutta, Sheetij, Morel, Sandra, van Helden, Mary J., Bourguignon, Patricia, Detienne, Sophie, Age K. Smilde, Franco, David, Van Deun, Katrijn, Smilde, Age AK, Sophie Detienne, Waters, Norman C, Deun, Katrijn Van, Arnaud M. Didierlaurent, Christopher J. Genito, van den Berg, Robert A, Dutta, Soumitra, Lambrecht, B.N., Chalon, Aurélie, Bart N. Lambrecht, Coccia, Marguerita, Goriely, S., Garçon, N., van den Berg, Robert, Catherine Collignon, van Helden, Mary, Robbert van der Most, van Helden, M.J., Hervé, Caroline, Lambrecht, Bart, Detienne, S., Dutta, S, Waters, N.C., Waters, Norman NC, Hervé, C., Franco, D., Van Deun, K., van den Berg, R.A., Collignon, C., Didierlaurent, A.M., Smilde, Age K, Chalon, A., Nathalie Garçon, Morel, S., Smilde, A.K., van Helden, M, Welsby, I., Genito, Christopher CJ, Genito, Christopher J, Sebbah, François-David FDS, Katrijn Van Deun, Coccia, M., Robert A. van den Berg, Genito, C.J., Patricia Bourguignon, Didierlaurent, Arnaud M., Aurélie Chalon, Waters, Norman C., Helden, Mary van MJV, Goriely, Stanislas, Caroline Hervé, Stanislas Goriely, Hervé, Cathérine, Iain Welsby, Norman C. Waters, David Franco, Dutta, S., Bourguignon, P., Berg, Robert A van den RAVD, Lambrecht, Bart N., Coccia, Margherita, Isaacs, John D., Collignon, Catherine   +84 more
core   +1 more source

Isolation and Genetic Identification of Phenol Degrading Bacterium from Wastewater of Assiut University Hospitals [PDF]

Egyptian Sugar Journal, 2020
Phenol and phenolic compounds are the most common pollutants in hospital wastewater. Their carcinogenic and toxic effects have been recorded on human being.
Ahmed Salah, Mohamed Abdel-Wahab, Abd El-Latif Heshame   +2 more
doaj   +1 more source

Immune response to the hepatitis B antigen in the RTS,S/AS01 malaria vaccine, and co-administration with pneumococcal conjugate and rotavirus vaccines in African children: A randomized controlled trial

Human Vaccines & Immunotherapeutics, 2018
The RTS,S/AS01 malaria vaccine (Mosquirix) reduces the incidence of Plasmodium falciparum malaria and is intended for routine administration to infants in Sub-Saharan Africa.
Innocent Valéa, Samuel Adjei, Effua Usuf, Ousmane Traore, Daniel Ansong, Halidou Tinto, Harry Owusu Boateng, Amanda Leach, Athanase Mwinessobaonfou Some, Patrick Buabeng, Johan Vekemans, Louis Arnaud Nana, Amos Kotey, Pascale Vandoolaeghe, Florence Ouedraogo, David Sambian, Marc Lievens, Marc Christian Tahita, Theresa Rettig, Erik Jongert, Palpouguini Lompo, Ali Idriss, Dorota Borys, Sayouba Ouedraogo, Frank Prempeh, Md Ahsan Habib, Lode Schuerman, Hermann Sorgho, Tsiri Agbenyega   +28 more
doaj   +1 more source

Malaria vaccine coverage estimation using age-eligible populations and service user denominators in Kenya

Malaria Journal, 2023
Background The World Health Organization approved the RTS,S/AS01 malaria vaccine for wider rollout, and Kenya participated in a phased pilot implementation from 2019 to understand its impact under routine conditions.
Angela K. Moturi, Rose Jalang’o, Anitah Cherono, Samuel K. Muchiri, Robert W. Snow, Emelda A. Okiro   +5 more
doaj   +1 more source

Acceptance, availability and feasibility of RTS, S/AS01 malaria vaccine: A review of literature

Asian Pacific Journal of Tropical Medicine, 2023
Malaria remains the most serious infectious disease and is one of the leading causes of death among children in malaria endemic areas. The development of malaria vaccines has been underway since 1960s.
Abdullah Nadeem, Wajeeha Bilal
doaj   +1 more source

Additional file 2 of Seven-year kinetics of RTS, S/AS01-induced anti-CSP antibodies in young Kenyan children

, 2021
Additional file 2.
Francis M. Ndungu (10827938), Philip Bejon (40508), Jedidah Mwacharo (66277), Juliana Wambua (174502), Faiz M. Shee (11787800), Robert M. Mugo (11787797), Kennedy Mwai (3162027), Jennifer N. Musyoki (11787806), Edward Otieno (10166476)   +8 more
core   +1 more source

RTS,S/AS01 Malaria Vaccine - The Next Step for a Developing Country [PDF]

, 2022
The paper puts spotlight on the new malarial vaccine RTS S/AS01 that can play a groundbreaking role in controlling malaria in the malarial endemic countries where a large portion of the native population suffers from this deadly infectious disease or its
SYED, BUSHRA, MASOOD, FAREEHA, ZEHRA, ASMAT   +2 more
core   +1 more source

The Ratiometric Transcript Signature MX2/GPR183 Is Consistently Associated With RTS,S-Mediated Protection Against Controlled Human Malaria Infection

Frontiers in Immunology, 2020
The RTS,S/AS01 vaccine provides partial protection against Plasmodium falciparum infection but determinants of protection and/or disease are unclear. Previously, anti-circumsporozoite protein (CSP) antibody titers and blood RNA signatures were associated
Ying Du, Ethan G. Thompson, Julius Muller, Joseph Valvo, Jackie Braun, Smitha Shankar, Robert A. van den Berg, Erik Jongert, Drew Dover, Jerald Sadoff, Jenny Hendriks, Malcolm J. Gardner, W. Ripley Ballou, Jason A. Regules, Robbert van der Most, Alan Aderem, Christian F. Ockenhouse, Adrian V. Hill, Ulrike Wille-Reece, Daniel E. Zak   +19 more
doaj   +1 more source

Beyond Spherical Harmonics: Rethinking Appearance Models for Radiance Reconstruction

Computer Graphics Forum, EarlyView.
Abstract View‐dependent appearance modeling remains a challenging problem in novel‐view synthesis and reconstruction. Accurately representing complex angular effects often requires substantial memory and computational resources. For new learning‐based methods, a common approach is to rely on Spherical Harmonics (SH).
Ewa Miazga, Jorge Condor, Piotr Didyk
wiley   +1 more source