Results 61 to 70 of about 4,126 (156)

Cancer Vaccine Development: Toward Artificial Intelligence‐Assisted Personalized Cell Membrane Nanovaccine

Small, Volume 22, Issue 49, 1 September 2026.
Cancer nanovaccines have emerged as promising alternatives to conventional cancer vaccines, which have shown limited clinical efficacy. In particular, cell membrane nanoparticle‐based nanovaccines can offer high biocompatibility and immunogenicity while preserving tumor antigens, including antigen repertoires.
Munsik Kim, Ilkoo Noh
wiley   +1 more source

Wafer‐Scale Near‐Infrared Metalenses With High Performance and Low Cost

Nanophotonics, Volume 15, Issue 16, 26 August 2026.
Widespread adoption of metalenses is constrained by prohibitive cost of wafer‐level fabrication. This work achieves 8‐inch wafer‐level fabrication with high uniformity (feature deviation < 5%) and reliable performance by step‐and‐repeat nanoimprint lithography.
Wanjiao Zhang, Meng Wang, Yunxiao Cai, Qiu Wang, Yuan Wang, Lu Han   +5 more
wiley   +1 more source

Enhancement of adaptive immunity by the human vaccine adjuvant AS01 depends on activated dendritic cells

, 2014
Adjuvant System AS01 is a liposome-based vaccine adjuvant containing 3-O-desacyl-4'-monophosphoryl lipid A and the saponin QS-21. AS01 has been selected for the clinical development of several candidate vaccines including the RTS, S malaria vaccine and ...
Dendouga, Najoua, Lambrecht, Bart, Malissen, Bernard, Fochesato, Michel, Didierlaurent, Arnaud M, Collignon, Catherine, Garçon, Nathalie, Wouters, Sandrine, Van Mechelen, Marcelle, Morel, Sandra, Bourguignon, Patricia, Fierens, Kaat, Langlet, Christelle   +12 more
core   +1 more source

RTS,S/AS01 malaria vaccine and child mortality

, 2015
Comment onEfficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial. [Lancet. 2015]
Rodrigues, Amabelia, Kofoed, Poul-Erik, Aaby, Peter, Benn, Christine Stabell   +3 more
core   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, Volume 150, Issue 7, Page 990-1015, August 2026.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine [PDF]

, 2015
The RTS,S/AS01 vaccine targets the circumsporozoite protein of Plasmodium falciparum and has partial protective efficacy against clinical and severe malaria disease in infants and children.
Neafsey, Daniel E., Griggs, Allison, Abdulla, Salim, Asante, Kwaku Poku, Aide, Pedro, Juraska, Michal, Agbenyega, Tsiri, Birkett, Ashley J., Bruls, Myriam, Aponte, John J., Dobaño, Carlota, Adjei, Samuel, D’Alessandro, Umberto, Greenwood, Brian, Leach, Amanda, Gesase, Samwel, Kariuki, Simon, Agnandji, Selidji T., Bejon, Philip, Grimsby, Jonna, Kamthunzi, Portia, Tinto, Halidou, Anderson, Scott, Bedford, Trevor, Kremsner, Peter G., Ansong, Daniel, Connolly, Kristen M., Benkeser, David, Lievens, Marc, Valim, Clarissa, Hamel, Mary J., Hoffman, Irving   +31 more
core   +1 more source

Combination of RTS,S and Pfs25-IMX313 Induces a Functional Antibody Response Against Malaria Infection and Transmission in Mice

Frontiers in Immunology, 2018
The last two decades saw a dramatic reduction in malaria incidence rates, but this decrease has been stalling recently, indicating control measures are starting to fail. An effective vaccine, particularly one with a marked effect on disease transmission,
Florian Brod, Kazutoyo Miura, Iona Taylor, Yuanyuan Li, Arianna Marini, Ahmed M. Salman, Alexandra J. Spencer, Carole A. Long, Sumi Biswas   +8 more
doaj   +1 more source

Impact of RTS,S/AS02(A) and RTS,S/AS01(B) on genotypes of P. falciparum in adults participating in a malaria vaccine clinical trial. [PDF]

PLoS ONE, 2009
RTS,S, a candidate vaccine for malaria, is a recombinant protein expressed in yeast containing part of the circumsporozoite protein (CSP) sequence of 3D7 strain of Plasmodium falciparum linked to the hepatitis B surface antigen in a hybrid protein.
John N Waitumbi, Samuel B Anyona, Carol W Hunja, Carolyne M Kifude, Mark E Polhemus, Douglas S Walsh, Chris F Ockenhouse, D Gray Heppner, Amanda Leach, Marc Lievens, W Ripley Ballou, Joe D Cohen, Colin J Sutherland   +12 more
doaj   +1 more source

Hit‐To‐Lead Optimization of a Pyridylpiperazine Class Against Malaria: Pharmacokinetic Profile and In Vivo Efficacy of Optimized Compounds

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Chemical optimization of a novel pyridylpiperazine class yields two promising antimalarial candidates with an exceptional balance of metabolic stability and solubility. These optimized leads significantly protect mice from cerebral malaria, reducing parasitic load by up to 91.7%.
Douglas Davison da Silva Oliveira, Duarte Eduardo Pereira, Rafael Consolin Chelucci, Simone Michelan, Júlia Maria Fernandes Pituba, Adriano D. Andricopulo, Leonardo L. G. Ferreira, Neide Maria Silva, Celso de Oliveira Rezende Júnior   +8 more
wiley   +1 more source

Malaria vaccines: the 60-year journey of hope and final success—lessons learned and future prospects

Tropical Medicine and Health, 2023
Background The world has made great strides towards beating malaria, although about half of the world population is still exposed to the risk of contracting malaria. Developing an effective malaria vaccine was a huge challenge for medical science.
Amal A. El-Moamly, Mohamed A. El-Sweify
doaj   +1 more source