Results 41 to 50 of about 209,148 (308)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Losses of thiamine, ascorbic acid and lysine in thermally sterilised foods [PDF]

open access: yes, 1982
The major objective of this investigation is the comparative nutritional evaluation of thermosterile foods in pouches and in cans during sterilization treatment and during storage.
Uribe de Saucedo, S   +1 more
core  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

HPTLC method for simultaneous determination of ascorbic acid and gallic acid biomarker from freeze dry pomegranate juice and herbal formulation

open access: yesSaudi Pharmaceutical Journal, 2019
A new rapid, simple, sensitive and high performance thin layer chromatography (HPTLC) has been established for the simultaneous determination of ascorbic acid and gallic acid in the freeze-dried pomegranate fruit juice and herbal formulation.
Prawez Alam   +5 more
doaj   +1 more source

APPLICATION OF MULTIVARIATE CALIBRATION AND DERIVATIVE ANALYSIS IN THE SPECTROPHOTOMETRIC DETERMINATION OF SOME ASCORBIC ACID PHARMACEUTICAL MIXTURES [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 2004
Two chemometric assisted spectrophotometric methods; multivariate calibration and zerocrossingfirst derivative analysis were applied for the determination of ascorbic acid (vitaminC) in its single pharmaceutical formulations and its simultaneous ...
Ibrahim Refaat
doaj   +1 more source

Ascorbic Acid degradation in orange and apple juices

open access: yes, 2022
The focus of this thesis was on vitamin C and the degradation of ascorbic acid in orange and apple juices. My research was on the effect of different temperatures on the Vitamin C content of apples and oranges during storage.
Ajayi, Margaret Opeyemi
core  

Jasmonic acid biosynthetic inhibitor ibuprofen inhibits the accumulation of ascorbic acid in strawberry fruit induced by lanthanum nitrate

open access: yes, 2023
By using jasmonic acid (JA) biosynthetic inhibitor ibuprofen (IBU), we investigated the roles of JA in the process of lanthanum nitrate (La(NO3)3)-regulated ascorbic acid (AsA) content and metabolic enzymes responsible for AsA metabolism in strawberry ...
Damiao Yuan, Changjuan Shan, Haifang Dai
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Carbon Tetrachloride Degradation by Alkaline Ascorbic Acid Solution

open access: yes, 2013
Ascorbic acid (AA) mediated electron transfer mayinduce reductive dechlorination of carbon tetrachloride (CCl4). Thisstudy investigated the role of AA in conjunction with the presence ofiron minerals over a wide pH range for the reduction of CCl4 ...
Ya-Ting Lin, Chenju Liang
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

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