Results 41 to 50 of about 167,391 (266)

Charting Morphotoxicity With Complementary Embryo Models

Advanced Healthcare Materials, EarlyView.
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx, Pauline L. Balder, Romy M. L. Verhagen, Vinidhra Shankar, Barry Jutten, Pinak Samal, Timo Rademakers, Clemens A. van Blitterswijk, Stefan Giselbrecht, Erik J. Vrij   +9 more
wiley   +1 more source

Supplementation of L-ascorbic acid improves the in vitro development of buffalo (Bubalus bubalis) embryos and alters the expression of apoptosis-related genes

Asian Pacific Journal of Reproduction, 2021
Objective: To study the effect of L-ascorbic acid supplementation on the in vitro development of buffalo embryos and evaluate the relative mRNA abundance of some pro-apoptotic, anti-apoptotic, and embryonic development-related genes.
Mayank Roshan, Diksha Dua, Ankur Sharma, Manish Tiwari, Manoj Kumar Singh, Suresh Kumar Singla, Prabhat Palta, Radhay Sham Manik, Manmohan Singh Chauhan   +8 more
doaj   +1 more source

Studies on Ascorbic Acid. VI

Journal of the agricultural chemical society of Japan, 1938
5mgのAscorbin酸の37±1°に於ける自己酸化に對しVitamin A原液(100,000 I.U.)を0.0～0.2cc作用せしむる時0.0～0.0005ccまでは自己酸化抑制作用は發現せず, 0.001ccに於いて漸く發現し而して0.12ccまではVitamin Aの作用量と共に抑制作用は増大し0.12ccに於いて最大點に達し0.14cc以上に於いては抑制作用は消滅し酸化促進作用と化し而も此の作用は量比的である.但し本實驗に於てはVitamin AのAceton溶液を用ゐたから實驗値に對して幾分の誤差はまぬかれないであらう.
openaire   +8 more sources

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source

Ascorbic acid alleviates rheumatoid arthritis by inhibiting the production of autoantibodies

Cell Communication and Signaling
Background Ascorbic acid can regulate the function of the immune system. This study aimed to investigate the underlying mechanisms of ascorbic acid in plasma cell differentiation and rheumatoid arthritis (RA). Methods Mice were intraperitoneally injected
Yuye Yin, Shusheng Wu
doaj   +1 more source

Ascorbic acid mitigates doxorubicin-induced spleen injury in rats: Histopathological and immunohistochemical insights

Pakistan Journal of Pharmaceutical Sciences
This study assessed the protective potential of ascorbic acid against doxorubicin-induced spleen tissue damage in rats. Twenty-eight male Sprague-Dawley rats were divided into four groups.
Arzu Gezer, Mustafa Ozkaraca, Ebru Karada Sari, Grsel Bedir, Pelin Aydn, Hasan Asker, AM Abd El-Aty   +6 more
doaj   +1 more source

Cellularized Skin Substitute Bioengineering for Regenerative Medicine: Cell Sources, Culture Strategies, and Transition Toward Defined, Xeno‐Free Culture Systems

Advanced Healthcare Materials, EarlyView.
Advances in cell sources, bioengineering, and manufacturing are reshaping the design of skin substitutes. This review highlights emerging strategies driving skin tissue engineering and discusses their potential to enable safer, reproducible, and clinically accessible skin substitutes for regenerative medicine.
Gilles Lemaître, Marina Trouillas, Tatiana Vinasco‐Sandoval, Cécile Giordano, Alexandre G. Lellouch, Walid Rachidi, Jean‐Jacques Lataillade, Nicolas O. Fortunel   +7 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

HPTLC method for simultaneous determination of ascorbic acid and gallic acid biomarker from freeze dry pomegranate juice and herbal formulation

Saudi Pharmaceutical Journal, 2019
A new rapid, simple, sensitive and high performance thin layer chromatography (HPTLC) has been established for the simultaneous determination of ascorbic acid and gallic acid in the freeze-dried pomegranate fruit juice and herbal formulation.
Prawez Alam, Y.T. Kamal, Saleh Ibrahim Alqasoumi, Ahmed Ibrahim Foudah, Mohammed Hamed Alqarni, Hasan Soliman Yusufoglu   +5 more
doaj   +1 more source

Recent Progress in the Phase‐Controlled Synthesis of Ruthenium Nanocrystals for Catalytic Applications

Advanced Materials, EarlyView.
Template effect and kinetic control enable crystal‐phase engineering of Ru nanocrystals, granting access to either metastable fcc‐Ru or stable hcp‐Ru with distinct surface structures, thermal stabilities, and catalytic behaviors. Moreover, the hcp‐Ru can further serve as an epitaxial template to direct Pd and Rh nanocrystals into the metastable hcp ...
Jianlong He, Zhiqi Wang, Jiaqi Guan, Younan Xia   +3 more
wiley   +1 more source