Results 231 to 240 of about 29,475 (304)

Plasmonic Heterojunction Nanomaterials for Noninvasive Pan‐Cancer Metabolomic Screening

Interdisciplinary Materials, EarlyView.
This study develops gold nanoparticle‐modified manganese–cobalt oxide heterjunctions (Au/MCOM) as a laser desorption/ionization mass spectrometry (LDI‐MS) matrix for acquiring serum metabolic fingerprints. Combined with machine learning, the platform achieves accurate detection and early screening across six cancer types, demonstrating strong potential
Jia Qi, Hairu Lin, Caiyun Fang, Jia Li, Fangying Shi, Chunhui Deng   +5 more
wiley   +1 more source

Oxygenation and Oxidation of Lignin Model Dimers by Fungal <i>Ortho</i>-Methoxyphenolases. [PDF]

J Am Chem Soc
de Oliveira Gorgulho Silva C, Bapat NA, Bourmaud CL, Nørskov Jensen C, Behaghel de Bueren J, Luterbacher J, Meyer AS, van Erven G, van Berkel WJH, Kabel MA, W Agger J.   +10 more
europepmc   +1 more source

Microbial metabolites in tumor epigenetic regulation

iMeta, EarlyView.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang, Haoling Zhang, Yan Liao, Shuya Jiang, Haolong Zhang, Chenwei Huang, Zhijing Song, Rui Zhao, Ping Lu, Xiaohong Kang, Eryan Kong, Yalin Zhu, Wei Wang, Xuesong Liu, Yisheng Chen, Zhiwen Luo, Zhaoyu Li, Di Wang, Na Xing, Yadong Guo, Jingjing Zhang, Xiaojing Wang, Wenyi Wang, Mowaffaq Adam, Bakiah Shaharuddin, Muhamad Yusri Musa, Doblin Sandai, Chenglong Zhu, Aimin Jiang, Peng Luo, Zhijie Zhao, Zui Zou   +31 more
wiley   +1 more source

Iron Deficiency Anaemia Screening and Management in Young Children: India and Southeast Asia Consensus. [PDF]

Anemia
Jalaludin MY, Mohamed HJJ, Taher SW, Ang K, Pechkethia L, Saengnipanthkul S, Phrasisombath K, Phengsavanh A, Bora R, Agarwalla SK.   +9 more
europepmc   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Case Report: Scurvy-a modifiable cause of psychiatric refractoriness and lithium pharmacokinetic abnormalities in autism. [PDF]

Front Psychiatry
Geiser M, Guggisberg N, Convertini J, Crettol S, Ansermot N, Guinchat V.   +5 more
europepmc   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

Optimizing Oral Vitamin C Supplementation: Addressing Pharmacokinetic Challenges with Nutraceutical Formulation Approaches-A Mini Review. [PDF]

Pharmaceutics
Dhotre T, Thanawala S, Shah R.
europepmc   +1 more source