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Genotype II Live-Attenuated ASFV Vaccine Strains Unable to Completely Protect Pigs against the Emerging Recombinant ASFV Genotype I/II Strain in Vietnam

Vaccines
Background: African swine fever virus (ASFV) continues to spread globally, causing severe economic losses to pig farmers. Vietnam licensed two live attenuated vaccines based on the ASFV strains ASFV-G-ΔI177L and ASFV-G-ΔMGF to control the ongoing ASF outbreaks.
Dung Nguyen, Kalhari Bandara Goonewardene, Aruna Ambagala   +2 more
exaly   +4 more sources

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Characterization of ASFV Proteins

1987
The analysis of polypeptides made in cells infected with African swine fever virus (ASFV) by high-resolution polyacrylamide gel electrophoresis revealed the synthesis of at least 44 polypeptides ranging in molecular weight from 9.5 K to 243 K. Most of the proteins are synthesized within the first eight hours after infection and can be classified as ...
openaire   +1 more source

Deoxycholic acid inhibits ASFV replication by inhibiting MAPK signaling pathway

International Journal of Biological Macromolecules
African swine fever (ASF) is an acute, febrile, highly contagious infection of pigs caused by the African swine fever virus (ASFV). The purpose of this study is to understand the molecular mechanism of ASFV infection and evaluate the effect of DCA on MAPK pathway, so as to provide scientific basis for the development of new antiviral drugs.
Qi, Gao, Yifan, Xu, Yongzhi, Feng, Xiaoyu, Zheng, Ting, Gong, Qiyuan, Kuang, Qinxin, Xiang, Lang, Gong, Guihong, Zhang   +8 more
openaire   +2 more sources

Unamplified system for sensitive and typing detection of ASFV by the cascade platform that CRISPR-Cas12a combined with graphene field-effect transistor

Biosensors and Bioelectronics, 2023
Shuo Chen, Lei Chen, Wenbo Sun
exaly  

Evaluation of the Deletion of MGF110-5L-6L on Swine Virulence from the Pandemic Strain of African Swine Fever Virus and Use as a DIVA Marker in Vaccine Candidate ASFV-G-ΔI177L

Journal of Virology, 2022
Elizabeth Ramirez-Medina, Ediane Silva, Lauro Velazquez-Salinas   +2 more
exaly  

Development of a Dual ELISA for the Detection of CD2v-Unexpressed Lower-Virulence Mutational ASFV

Life, 2021
Changjie Lv, Chao Wu
exaly  

Deletion of the ASFV dUTPase Gene E165R from the Genome of Highly Virulent African Swine Fever Virus Georgia 2010 Does Not Affect Virus Replication or Virulence in Domestic Pigs

Viruses, 2022
Elizabeth Ramirez-Medina, Ediane Silva, Douglas P Gladue   +2 more
exaly  

Virabloc impacts viability of an ASFV surrogate (Emiliania huxleyi) virus in feed: Implications for ASFV transmission in today’s global supply chain

AASV Annual Meeting, 2023
A. Wagner, C. Balestreri, I. Girard, E. Groos, K. Schuman, D. Schroeder   +5 more
openaire   +1 more source

African swine fever virus (ASFV) protection mediated by NH/P68 and NH/P68 recombinant live-attenuated viruses

Vaccine, 2018
Carmina Gallardo, Daniel Pérez-Núñez, Patricia de Leon   +2 more
exaly  

Inhibition of cGAS-STING-TBK1 signaling pathway by DP96R of ASFV China 2018/1

Biochemical and Biophysical Research Communications, 2018
Xixi Wang
exaly