Results 191 to 200 of about 9,741 (217)

Deletion of African Swine Fever Virus (ASFV) H240R Gene Attenuates the Virulence of ASFV by Enhancing NLRP3-Mediated Inflammatory Responses

Journal of Virology, 2023
African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious and acute hemorrhagic viral disease of domestic pigs, with a high mortality approaching 100%. ASFV has spread rapidly worldwide and caused huge economic losses and ecological consequences.
Zilong Wang, Dongming Zhao, Liang Hu
exaly   +3 more sources

Regulation of antiviral immune response by African swine fever virus (ASFV)

Virologica Sinica, 2022
African swine fever (ASF) is a highly contagious and acute hemorrhagic viral disease with a high mortality approaching 100% in domestic pigs. ASF is an endemic in countries in sub-Saharan Africa. Now, it has been spreading to many countries, especially in Asia and Europe.
Wen-hai Feng
exaly   +3 more sources

ASFV MGF360

2022
用于建立检测ASFV的荧光PCR方法的目的片段
openaire   +1 more source

Identification and utility of innate immune system evasion mechanisms of ASFV

Virus Research, 2013
The interferon (IFN) system is an early innate anti-virus host defense mechanism that takes place shortly after entry of the pathogen and long before the onset of adaptive immunity. Thus, African swine fever virus (ASFV), as an acute and persistent virus in pigs, is predicted to have evolved multiple genes for the manipulation and evasion of interferon.
Silvia Correia
exaly   +3 more sources

ASFV complete genomes sequences alignment

2020
ASFV complete genomes sequences ...
Aslanyan Levon, Hakobyan Hranush, Karalyan Zaven   +2 more
openaire   +1 more source

ZBP1-mediated macrophage necroptosis inhibits ASFV replication

2023
AbstractAfrican swine fever (ASF) is an infectious disease characterized by hemorrhagic fever, highly pathogenic, and severe mortality in domestic pigs caused by the African swine fever virus (ASFV). ASFV is a large DNA virus and primarily infects porcine monocyte macrophages.
Keshan Zhang, Yu Hao, Bo Yang, Jinke Yang, Dajun Zhang, Xing Yang, Xijuan Shi, Dengshuai Zhao, Lingling Chen, Wenqian Yan, Yi Ru, Zixiang Zhu, Xiaodong Qin, Huanan Liu, Fan Yang, Dan Li, Hong Tian, Tao Feng, Jianhong Guo, Jijun He, Xiangtao Liu, Haixue Zheng   +21 more
openaire   +1 more source

Quantification of ASFV DNA and RNA in Ornithodoros Soft Ticks

2022
Molecular biology methods are highly sensitive to detect the genome of pathogens and to study their biology. Polymerase chain reaction (PCR) and reverse transcription followed by a polymerase chain reaction (RT-PCR) permit the detection of the presence and the replication of African swine fever virus in soft ticks.
Pereira de Oliveira, Rémi, Vial, Laurence, Le Potier, Marie-Frédérique   +2 more
openaire   +5 more sources

ASFV p30 interacts with CCAR2 and MATR3 to promote ASFV replication

Veterinary Microbiology
African swine fever (ASF) is a highly contagious and lethal disease caused by the African swine fever virus (ASFV). Currently, effective vaccines are not available for the prevention and control of ASF. ASFV is susceptible to mutations as it has a large genome and encodes numerous proteins. In addition to evading the host immune response, ASFV utilizes
Xuefei, Chu, Shengqiang, Ge, Bingrong, Wu, Yuanyuan, Zuo, Tiangang, Xu, Jiarong, Yu, Lei, Yin, Hailong, Qu, Jinming, Li, Yihong, Xiao, Zhiliang, Wang   +10 more
openaire   +2 more sources

ASFV subunit vaccines: Strategies and prospects for future development

Microbial Pathogenesis
African Swine Fever (ASF) is an acute, highly contagious, and lethal disease caused by the African Swine Fever Virus (ASFV), posing a severe threat to the global pig farming industry. Although live vaccines are currently available, preventing and controlling ASF remains a considerable challenge.
Yuchen Zhang, Xiuzhen Mei, Chao Zhang, Hui Wang, Xing Xie, Zhenzhen Zhang, Zhixin Feng   +6 more
openaire   +2 more sources

Porcine immune responses to African swine fever virus (ASFV) infection

Veterinary Immunology and Immunopathology, 1994
Immune responses mediating protection against ASFV are poorly understood. Anti-ASFV antibodies may influence the course of the clinical disease but they have never been found to neutralize the virus. Recent developments on cellular defense mechanisms, using swine protection models, and on the induction and role of some cytokines warrant further ...
C L, Martins, A C, Leitão
openaire   +2 more sources