Results 41 to 50 of about 2,786 (162)

Immunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications

Phytotherapy Research, EarlyView.
ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta, Sonalika Gupta, Gagandeep Kaur, Partha Sarathi Mondal, Milirani Das, Anagha Ranade, Alok Kumar Srivastava, Sachin Kumar, Manoj Kumar Barthwal, Madhu Dikshit   +9 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Ashwagandha (Withania somnifera) – a herb with versatile medicinal properties empowering human physical and mental health

Journal of Pre-Clinical and Clinical Research, 2021
Introduction Ashwagandha is a rasayana of Ayurveda system of medicines. It is a real potent regenerative tonic possessing several pharmacological properties like neuro-protective, anti-stress, anti-arthritic, antitumor, analgesic and anti-inflammatory.
Sonu Gupta, Ravinder Nath Bansal, Surender Pal Singh Sodhi, Gursimrat Kaur Brar, Mehak Malhotra   +4 more
doaj   +1 more source

Dietary Patterns and Food Choices of Adults With Inflammatory Bowel Disease in New Zealand

JGH Open, Volume 10, Issue 8, August 2026.
ABSTRACT Aims This study aimed to assess current dietary patterns in adults with inflammatory bowel disease (IBD) in New Zealand and to evaluate associations with current self‐reported disease activity and well‐being. Methods A prospective online survey was conducted using validated dietary data collection instruments.
Peter Vivian Acire, Angharad Vernon‐Roberts, Andrew S. Day   +2 more
wiley   +1 more source

Evaluating the efficacy of Ashwagandha Thailam for alleviating burning feet

Journal of Research in Traditional Medicine
Background: Burning feet, described by sensations of heat, pain, or discomfort in the soles, is a prevalent condition with various causative factors including peripheral neuropathy, diabetes mellitus, vitamin deficiencies, alcohol abuse, and nerve ...
Raja Amarnath, Aiswarya Ravichandran, Waheb Sheik Fazil, Poorni Chinnadurai, Asuwathy Sivasubramaniam, Manish Manchireddy   +5 more
doaj   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, Volume 40, Issue 8, Page 4792-4801, August 2026.
ABSTRACT The preclinical evidence for the safety of ashwagandha ( Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports. Most studies and reviews conclude
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Ashwagandha under fire: A critical scientific analysis of regulatory decisions

International Journal of Ayurveda Research
Ashwagandha (Withania somnifera [L.] Dunal) is one of the most renowned Ayurvedic medicinal plants, extensively used in traditional Indian medicine systems such as Ayurveda, Siddha, Unani, and Sowa Rigpa for millennia.
Jorge Luis Berra, Silvia Chernigoy, Karina Alvarez, Maria Jose Wernisch   +3 more
doaj   +1 more source

Safety of 12‐Months Administration of Ashwagandha ( Withania somnifera ) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, Volume 40, Issue 8, Page 4802-4812, August 2026.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

Unlocking Strength: The Powerful Impact of Ashwagandha (Withania somnifera) Supplementation on Resistance Training

Journal of Education, Health and Sport
Withania somnifera, commonly known as ashwagandha, has gained popularity in recent years among individuals interested in healthy lifestyles, natural medicine, and sports.
Piotr Sikorski, Piotr Malinowski, Urszula Kopczyńska, Cezary Kopczyński, Kinga Gurdak, Martyna Dydyk, Martyna Dyrek, Ewa Błaszczak, Jakub Wójcik, Aleksandra Partyka   +9 more
doaj   +1 more source

Ashwagandha: Is It Safe? Part 1: A Regulatory Review

Phytotherapy Research, Volume 40, Issue 8, Page 4845-4857, August 2026.
ABSTRACT Over the last decade, ashwagandha ( Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler, R. Al‐Mondhiry, L. Lang, R. Marles, M. Tallon, A. Raghu   +5 more
wiley   +1 more source