Virology Journal, 2023 Background Several anti-retroviral drugs are available against Human immunodeficiency virus type-1, but have multiple adverse side effects. Hence, there is an incessant compulsion for effectual anti-retroviral agents with minimal or no intricacy ...
Pratiksha Jadaun +8 more
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The effect of Withania somnifera (Ashwagandha) on mental health symptoms in individuals with mental disorders: systematic review and meta-analysis [PDF]
BJPsych OpenBackground Withania somnifera (WS) is considered an adaptogen agent with reported antistress, cognition facilitating and anti-inflammatory properties, which may be beneficial in the treatment of mental disorders.
Mattia Marchi +9 more
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Investigating the genetic potential of Ashwagandha (Withania somnifera L. Dunal) germplasm through SCoT and EST-SSR molecular markers [PDF]
Scientific ReportsAshwagandha (Withania somnifera L. Dunal) is a highly acclaimed medicinal herb belonging to the family Solanaceae. The plant has been rendered an essential component of the Indian medicinal system due to its high therapeutic potential, attributed to its ...
Trapti Mandliya +3 more
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TRAIL-resistant glioma cells resist Withania somnifera mediated apoptosis via USP5 upregulation [PDF]
Scientific ReportsThe tumor necrosis factor related apoptosis inducing ligand (TRAIL) shows a potential therapeutic by inducing apoptosis in glioma cells and sparing normal cells, but TRAIL resistance and chemotherapeutic resistance still prevails in glioma and hinder its
Sachin Bhardwaj, Ajay Kumar Yadav
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Frontiers in Cellular and Infection Microbiology, 2022 Coronavirus disease 2019 (COVID-19) pandemic has killed huge populations throughout the world and acts as a high-risk factor for elderly and young immune-suppressed patients.
Manali Singh +16 more
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NAJFNR, 2022 Background: Withania somnifera has been used as an ergogenic resource in recent years. In this scenario, a systematic literature review is justified to compile the findings in the scientific literature and to evaluate the methodological quality of these
Fábio Pieluhowski Didio +2 more
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Evaluation of Analgesic Activity of Standardised Aqueous Extract of Withania somnifera in Healthy Human Volunteers using Mechanical Pain Model [PDF]
Journal of Clinical and Diagnostic Research, 2019 Introduction: Drugs commonly used for pain management are associated with adverse effects. Experimental pain models in human healthy volunteers are advantageous for early evaluation of analgesics. Studies with Withania somnifera have demonstrated that it
Manjunath Nookala Krishna murthy +3 more
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Evaluating anticancer properties of Withaferin A—a potent phytochemical
Frontiers in Pharmacology, 2022 Withaferin A is a C28 steroidal lactone derived from the plant Withania somnifera, commonly known as Ashwagandha. Withaferin A has received great attention for its anticancer properties noted in cancer cells of various origins.
Maushma Atteeq
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QUANTITIVE EVOLUTION OF WITHANOLIDES CONTENT OF EGYPTIAN WITHANIA SOMNIFERA (L.) ROOTS. [PDF]
Al-Azhar Journal of Pharmaceutical Sciences, 2013 Withanolides are important secondary metabolite in Withania somnifera (L.), which have high medicinal values and possess potent anti-tumor and antioxidant properties.
Said Ismail
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RNAi and Homologous Over-Expression Based Functional Approaches Reveal Triterpenoid Synthase Gene-Cycloartenol Synthase Is Involved in Downstream Withanolide Biosynthesis in Withania somnifera. [PDF]
PLoS ONE, 2016 Withania somnifera Dunal, is one of the most commonly used medicinal plant in Ayurvedic and indigenous medicine traditionally owing to its therapeutic potential, because of major chemical constituents, withanolides.
Smrati Mishra +6 more
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