Results 1 to 10 of about 4,956 (112)

Withania somnifera (L.) Dunal (Ashwagandha) for the possible therapeutics and clinical management of SARS-CoV-2 infection: Plant-based drug discovery and targeted therapy

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Coronavirus disease 2019 (COVID-19) pandemic has killed huge populations throughout the world and acts as a high-risk factor for elderly and young immune-suppressed patients.
Manali Singh   +16 more
doaj   +1 more source

Effects of the Withania somnifera supplementation on sports performance: a systematic review and meta-analysis

open access: yesNAJFNR, 2022
Background: Withania somnifera has been used as an ergogenic resource in recent years. In this scenario, a systematic literature review is justified to compile the findings in the scientific literature and to evaluate the methodological quality of these
Fábio Pieluhowski Didio   +2 more
doaj   +1 more source

Evaluation of Analgesic Activity of Standardised Aqueous Extract of Withania somnifera in Healthy Human Volunteers using Mechanical Pain Model [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2019
Introduction: Drugs commonly used for pain management are associated with adverse effects. Experimental pain models in human healthy volunteers are advantageous for early evaluation of analgesics. Studies with Withania somnifera have demonstrated that it
Manjunath Nookala Krishna murthy   +3 more
doaj   +1 more source

Withania somnifera extracts induced attenuation of HIV-1: a mechanistic approach to restrict viral infection

open access: yesVirology Journal, 2023
Background Several anti-retroviral drugs are available against Human immunodeficiency virus type-1, but have multiple adverse side effects. Hence, there is an incessant compulsion for effectual anti-retroviral agents with minimal or no intricacy ...
Pratiksha Jadaun   +8 more
doaj   +1 more source

Evaluating anticancer properties of Withaferin A—a potent phytochemical

open access: yesFrontiers in Pharmacology, 2022
Withaferin A is a C28 steroidal lactone derived from the plant Withania somnifera, commonly known as Ashwagandha. Withaferin A has received great attention for its anticancer properties noted in cancer cells of various origins.
Maushma Atteeq
doaj   +1 more source

QUANTITIVE EVOLUTION OF WITHANOLIDES CONTENT OF EGYPTIAN WITHANIA SOMNIFERA (L.) ROOTS. [PDF]

open access: yesAl-Azhar Journal of Pharmaceutical Sciences, 2013
Withanolides are important secondary metabolite in Withania somnifera (L.), which have high medicinal values and possess potent anti-tumor and antioxidant properties.
Said Ismail
doaj   +1 more source

RNAi and Homologous Over-Expression Based Functional Approaches Reveal Triterpenoid Synthase Gene-Cycloartenol Synthase Is Involved in Downstream Withanolide Biosynthesis in Withania somnifera. [PDF]

open access: yesPLoS ONE, 2016
Withania somnifera Dunal, is one of the most commonly used medicinal plant in Ayurvedic and indigenous medicine traditionally owing to its therapeutic potential, because of major chemical constituents, withanolides.
Smrati Mishra   +6 more
doaj   +1 more source

Investigation of Withania Somnifera Extract as Corrosion Inhibitor for Copper in Nitric Acid Solutions

open access: yesInternational Journal of Electrochemical Science, 2019
Corrosion inhibitive effect of Withania Somnifera extract has been studied in 0.5 M nitric acid for Copper (Cu). The studies were done at different temperatures (30-50oC). The thermodynamic parameters were determined. Withania Somnifera has been found to
H.M. Elabbasy
doaj   +1 more source

The immunomodulatory role of withania somnifera (L.) dunal in inflammatory diseases

open access: yesFrontiers in Pharmacology, 2023
Withania somnifera (L.) Dunal (Solanaceae) (also known as Ashwagandha) is a botanical drug that has been used for centuries to treat many chronic diseases like high blood pressure, arthritis, diabetes, Alzheimer’s disease, and depression.
Hamad H. Alanazi, Elyasa Elfaki
doaj   +1 more source

Nitric oxide induced by Indian ginseng root extract inhibits Infectious Bursal Disease virus in chicken embryo fibroblasts in vitro

open access: yesJournal of Animal Science and Technology, 2018
Infectious Bursal Disease is a severe viral disease of chicken responsible for serious economic losses to poultry farmers. The causative agent, Infectious Bursal Disease virus, is inhibited by nitric oxide.
Bhaskar Ganguly   +2 more
doaj   +1 more source

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