Results 41 to 50 of about 4,956 (112)

Evaluation of Withaferin A Content in Withania somnifera Using NMR and HPLC: A Comparative Assessment of Traditional and PCSL Extraction Methods

open access: yesChemistry &Biodiversity, Volume 23, Issue 6, June 2026.
A comparative evaluation of traditional aqueous extractions and innovative pressurised cyclic solid–liquid extraction is presented for Withania somnifera leaves. Quantitative NMR, validated by HPLC, reveals a markedly enhanced preservation and recovery of withaferin A using PCSL.
Silvana Pedatella   +4 more
wiley   +1 more source

Allelopathic Influence of Withania somnifera Leaf Extracts on the Germination and Seedling Growth of Wheat Genotypes

open access: yesInternational Journal of Economic Plants
The experiment was conducted from February to March, 2023 in Lab-02, Department of Plant Physiology and Biochemistry, Bihar Agricultural University, Sabour, Bhagalpur, Bihar, India, to study the allelopathic properties of Ashwagandha on germination and ...
M. P. Mandal, S. K. Bharti
doaj   +1 more source

Red light controlled callus morphogenetic patterns and secondary metabolites production in Withania somnifera L.

open access: yesBiotechnology Reports, 2019
Withania somnifera L. is an endangered medicinal plant of higher market value. The in vitro callus cultures were established on Murashige and Skoog (MS) media augmented with different plant growth regulators.
Muhammad Adil   +2 more
doaj   +1 more source

Vacuolization as a Novel Approach to Cancer Therapy

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak   +9 more
wiley   +1 more source

Chemical Composition, Biological Activity, and Health-Promoting Effects of Withania somnifera for Pharma-Food Industry Applications

open access: yesJournal of Food Quality, 2021
The Withania genus comes from the Solanaceae family and includes around 23 species, spread over some areas of the Mediterranean, Asia, and East Africa.
Javad Sharifi-Rad   +21 more
doaj   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

open access: yesPhytochemical Analysis, Volume 37, Issue 4, Page 507-535, June 2026.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek   +3 more
wiley   +1 more source

Current and future prospectus of Withania somnifera L.: An overview

open access: yesEnvironment Conservation Journal
Withania somnifera (L.) is one of the most important medicinal crops used as an immunity booster and also known as Indian ginseng due to its potential to relax the mind, relieve stress and exhaustion, improve sexual energy, and reduce insomnia.
R. K. Upadhyay, Pragya Pandey
doaj   +1 more source

Natural Monoterpene Stylosin Induced Anticancer Effects on Human Colon Carcinoma Cells

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Extraction of STL from Ferula ovina by TLC and structural confirmation by 1H NMR. Favorable pharmacokinetics. Reduced CRC cell viability in a time‐ and dose‐dependent manner. Induced apoptosis. Interacted with the active site of HGFR. ABSTRACT Colorectal carcinoma (CRC) ranks among the top five most common malignancies globally, characterized by a high
Sara Seyedshazileh   +3 more
wiley   +1 more source

Protective Effects of Withania Somnifera Against Cisplatin-Induced Acute Kidney Injury in Rats: A Histomorphometric Analysis

open access: yesLife and Science
Objective: This research aims to analyze the toxic effects of cisplatin and its amelioration by the root extract of Withania Somnifera on acute kidney injury in rat models through histomorphometric parameters. Study Design:  Experimental study. Place and
Aaqiba Rasheed   +6 more
doaj   +1 more source

Anxiolytic and Memory Protective Effects of Withanolide D Isolated From Acnistus arborescens in Adult Zebrafish

open access: yesChemistry &Biodiversity, Volume 23, Issue 5, May 2026.
Withanolide D Exhibits Anxiolytic and Memory‐Protective Effects. ABSTRACT This study evaluated the anxiolytic and memory‐protective effects of withanolide D in adult zebrafish (Danio rerio). The compound was administered at doses of 4, 20, and 40 mg/kg and showed no signs of toxicity after 96 h of observation at any of the doses tested.
Cléia Rocha de Sousa Feitosa   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy