Results 91 to 100 of about 11,688 (172)

NEK8 promotes the progression of gastric cancer by reprogramming asparagine metabolism

Molecular Medicine
Several members of the NIMA-related kinase (NEK) family have been implicated in tumor progression; however, the role and underlying mechanisms of NEK8 in gastric cancer (GC) remain unclear.
Mingliang Wang, Kexun Yu, Futao Meng, Huizhen Wang, Yongxiang Li   +4 more
doaj   +1 more source

Case report: A compound heterozygous mutations in ASNS broadens the spectrum of asparagine synthetase deficiency in the prenatal diagnosis. [PDF]

Front Pediatr, 2023
Zhu L, Sun Y, Xu Y, Jin P, Ding H, Dong M.   +5 more
europepmc   +1 more source

A method for measurement of human asparagine synthetase (ASNS) activity and application to ASNS protein variants associated with ASNS deficiency. [PDF]

Biol Methods Protoc, 2023
Chang MC, Staklinski SJ, Merritt ME, Kilberg MS.   +3 more
europepmc   +1 more source

Asparagine drives immune evasion in bladder cancer via RIG-I stability and type I IFN signaling

The Journal of Clinical Investigation
Tumor cells often employ many ways to restrain type I IFN signaling to evade immune surveillance. However, whether cellular amino acid metabolism regulates this process remains unclear, and its effects on antitumor immunity are relatively unexplored ...
Wenjie Wei, Hongzhao Li, Shuo Tian, Chi Zhang, Junxiao Liu, Wen Tao, Tianwei Cai, Yuhao Dong, Chuang Wang, Dingyi Lu, Yakun Ai, Wanlin Zhang, Hanfeng Wang, Kan Liu, Yang Fan, Yu Gao, Qingbo Huang, Xin Ma, Baojun Wang, Xu Zhang, Yan Huang   +20 more
doaj   +1 more source

Malignant ascites supernatant enhances the proliferation of gastric cancer cells partially via the upregulation of asparagine synthetase. [PDF]

Oncol Lett, 2023
Jiao Y, Peng X, Wang Y, Hao Z, Chen L, Wu M, Zhang Y, Li J, Li W, Zhan X.   +9 more
europepmc   +1 more source

Primary cilia sense glutamine availability and respond via asparagine synthetase. [PDF]

Nat Metab, 2023
Steidl ME, Nigro EA, Nielsen AK, Pagliarini R, Cassina L, Lampis M, Podrini C, Chiaravalli M, Mannella V, Distefano G, Yang M, Aslanyan M, Musco G, Roepman R, Frezza C, Boletta A.   +15 more
europepmc   +1 more source

Asparagine Synthetase [Glutamine-Hydrolyzing] [PDF]

, 2020
openaire   +1 more source

Transcriptional repressor RST1 controls salt tolerance and grain yield in rice by regulating gene expression of asparagine synthetase. [PDF]

Proc Natl Acad Sci U S A, 2022
Deng P, Jing W, Cao C, Sun M, Chi W, Zhao S, Dai J, Shi X, Wu Q, Zhang B, Jin Z, Guo C, Tian Q, Shen L, Yu J, Jiang L, Wang C, Chin JH, Yuan J, Zhang Q, Zhang W.   +20 more
europepmc   +1 more source

Asparagine synthetase regulates lung-cancer metastasis by stabilizing the β-catenin complex and modulating mitochondrial response. [PDF]

Cell Death Dis, 2022
Cai DJ, Zhang ZY, Bu Y, Li L, Deng YZ, Sun LQ, Hu CP, Li M.   +7 more
europepmc   +1 more source

Consumption of meat containing ractopamine might enhance tumor growth through induction of asparagine synthetase. [PDF]

Eur J Cancer Prev, 2022
Fan FS.
europepmc   +1 more source