Results 81 to 90 of about 414,727 (380)

Low aspartate aminotransferase/alanine aminotransferase (DeRitis) ratio assists in predicting diabetes in Chinese population

Frontiers in Public Health, 2022
BackgroundFew studies discussed the predictive ability of aspartate aminotransferase/alanine aminotransferase (AST/ALT, DeRitis) ratio for diabetes risk.
Wangcheng Xie, Weidi Yu, Shanshan Chen, Zhilong Ma, Tingsong Yang, Zhenshun Song   +5 more
doaj   +1 more source

Assessing Non-Invasive Liver Function in Patients With Intestinal Failure Receiving Total Parenteral Nutrition-Results From the Prospective PNLiver Trial [PDF]

, 2020
Liver abnormalities in intestinal failure (IF) patients receiving parenteral nutrition (PN) can progress undetected by standard laboratory tests to intestinal failure associated liver disease (IFALD). The aim of this longitudinal study is to evaluate the
Bednarsch, Jan, Blüthner, Elisabeth, Gerlach-Runge, Undine, Karber, Mirjam, Maasberg, Sebastian, Pape, Ulrich-Frank, Pascher, Andreas, Pevny, Sophie, Pratschke, Johann, Stockmann, Martin, Tacke, Frank   +10 more
core   +1 more source

Imaging of Lipid Droplets in Living Cells and Mice with Metabolic Dysfunction‐Associated Steatotic Liver Disease via a Galactose‐Modified Supramolecular Near‐Infrared Fluorescent Glycoprobe

Advanced Functional Materials, EarlyView.
A galactose‐modified supramolecular near‐infrared (NIR) glycoprobe, TCF‐FBN@Gal‐BSA, enables targeted delivery to the liver through the asialoglycoprotein receptor (ASGPR) and facilitates liver‐targeting fluorescence visualization of lipid droplets (LDs) in metabolic dysfunction‐associated steatotic liver disease (MASLD) mice.
Han‐Min Wang, Lei Dong, Qiu‐Lian Hao, Lu‐Lu Sun, Xin‐Rong Li, Yu‐Wei Yuan, Ming‐Ye Tang, Jin Gong, Yi Zang, Jia Li, Tony D. James, Xiao‐Peng He, Hai‐Hao Han   +12 more
wiley   +1 more source

The malate–aspartate shuttle (Borst cycle): How it started and developed into a major metabolic pathway

IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2020
This article presents a personal and critical review of the history of the malate–aspartate shuttle (MAS), starting in 1962 and ending in 2020. The MAS was initially proposed as a route for the oxidation of cytosolic NADH by the mitochondria in Ehrlich ...
P. Borst
semanticscholar   +1 more source

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

Advanced Functional Materials, EarlyView.
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao, Maoze Wang, Jinling Huang, Yu Wang, Jing Zhao, Ran Wang, Zhi Ping Xu, Jianping Jiang, Lingxiao Zhang   +8 more
wiley   +1 more source

Pengaruh Penambahan Tepung Daun Kelor (Moringa oleifera) pada Pakan Tikus Putih Terhadap Aktivitas Enzim Alanin Aminotransferase dan Aspartate Aminotransferase

Indonesia Medicus Veterinus, 2018
Penelitian ini menggunakan 25 ekor tikus putih betina, masing-masing kelompok terdiri atas lima ekor tikus putih betina P0 (hewan coba diberikan pakan tanpa penambahan tepung daun kelor), P1 (pakan di tambahkan tepung daun kelor 2,5 %) P2 (pakan di ...
Asri Setiyowati, Iwan Harjono Utama, Ni Luh Eka Setiasih   +2 more
doaj  

The Effect of Ramadan Fast on Serum liver Enzyme Levels in Iranian Adults [PDF]

Journal of Research in Applied and Basic Medical Sciences, 2021
Background & Aims:  Ramadan fasting has numerous health benefits. Nevertheless, its beneficial role on liver function was evaluated by limited studies and different findings were recorded.
Mahshid Mohammadian, Sadegh Feizollah zadeh, Javad Rasuli, Mohammad Aziz Rasouli, Mohammad Alizadeh   +4 more
doaj  

The ratio of aspartate aminotransferase to alanine aminotransferase (AST/ALT): the correlation of value with underlying severity of alcoholic liver disease.

Kathmandu University Medical Journal, 2015
BACKGROUND Alcoholic liver disease is one of the most frequently diagnosed liver problems in the hospitalized patients in most tertiary care hospitals all over the world .The diagnosis of alcoholic liver disease is most of the time clinical.
R. Gurung, B. Purbe, P. Gyawali, P. Risal   +3 more
semanticscholar   +1 more source

A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia. [PDF]

, 2016
Acute myeloid leukemia (AML) cells meet the higher energy, metabolic, and signaling demands of the cell by increasing mitochondrial biogenesis and mitochondrial protein translation.
Brandwein, Joseph, Douer, Dan, Gronda, Marcela, Gupta, Vikas, Hurren, Rose, Jitkova, Yulia, Kambhampati, Suman, Minden, Mark D, Reed, Gregory A, Schiller, Gary J, Schimmer, Aaron D, Schuh, Andre C, Shamas-Din, Aisha, Tallman, Martin S, Yee, Karen W   +14 more
core   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source