Results 41 to 50 of about 186,010 (406)

Liver enzymes, metabolomics and genome-wide association studies: From systems biology to the personalized medicine. [PDF]

, 2015
For several decades, serum levels of alanine (ALT) and aspartate (AST) aminotransferases have been regarded as markers of liver injury, including a wide range of etiologies from viral hepatitis to fatty liver.
Pirola, Carlos José, Sookoian, Silvia Cristina   +1 more
core   +1 more source

The sequences of the coenzyme-binding peptide in the cytoplasmic and the mitochondrial aspartate aminotransferases from sheep liver.

Biochemical Journal, 1975
The sequences of the coenzyme-binding peptide of both cytoplasmic and mitochondrial aspartate aminotransferases from sheep liver were determined. The holoenzymes were treated with NaBH4 and digested with chymotrypsin; peptides containing bound pyridoxal ...
M. Campos-Cavieres, C. Milstein
semanticscholar   +1 more source

Hepato-Protective Effects of Silymarin and Coffee in Rats

Journal of Islamic International Medical College, 2021
Objective: To compare the effects of silymarin and coffee on liver enzymes in acetaminophen-induced hepatotoxicity in rats. Study Design: Experimental-randomized control study.
Sidra Mumal, Akbar Waheed, Abdul Azeem, Hira Waqas Cheema, Fakhra Noureen, Abeera Zainab
doaj  

Arterial blood pressure waveform in liver transplant surgery possesses variability of morphology reflecting recipients' acuity and predicting short term outcomes [PDF]

arXiv, 2021
Background: We investigated clinical information underneath the beat-to-beat fluctuation of the arterial blood pressure (ABP) waveform morphology. We proposed the Dynamical Diffusion Map algorithm (DDMap) to quantify the variability of morphology. The underlying physiology could be the compensatory mechanisms involving complex interactions between ...
arxiv  

Immunoglobulin-Complexed Aspartate Aminotransferase.

Internal Medicine, 1993
We report a case of increased aspartate aminotransferase (AST, EC 2.6.1.1; GOT) in a 17-year-old girl which persisted for 3 years. The patient was healthy, but a high level of serum AST was detected during a school health check. Further examination revealed that AST was increased to as high as 259 IU/l while alanine aminotransferase (ALT) was normal ...
Satoshi Tanabe, Sumio Matama, Katsunori Saigenji, Hitoshi Ito, Muneo Hasegawa, Akitaka Shibuya, Keizo Sakurai, Hisao Shibata   +7 more
openaire   +3 more sources

Should patients with abnormal liver function tests in primary care be tested for chronic viral hepatitis: cost minimisation analysis based on a comprehensively tested cohort [PDF]

, 2011
Background Liver function tests (LFTs) are ordered in large numbers in primary care, and the Birmingham and Lambeth Liver Evaluation Testing Strategies (BALLETS) study was set up to assess their usefulness in patients with no pre-existing or self ...
AA Butt, Alan J Girling, B Weber, C Trepo, CS Wang, D Lavanchy, David T Arnold, DJ McLernon, DR Dufour, DS Pratt, DW Hutton, E Castelnuovo, E Tanaka, E Yano, EG Giannini, F Kanwal, FJ de Serres, GA Poland, GJ Dore, GM Pendino, HC Kim, IK Veldhuijzen, J Nakamura, J Thompson Coon, JK Limdi, JV Metcalf, K Stein, K Witte, KJ Petrie, KM Kim, L Olivarez, Louise M Bentham, M Persico, M Weinstein, M Worwood, MW Whitehead, P Sherwood, PM Todd, PT Donnan, R D'Souza, R Hultcrantz, R Jamali, RG Newcombe, Richard J Lilford, RM Theal, Ruth P Jacob, S Bellentani, S Daniel, SN Lu, UL Mathiesen, World Health Organization, World Health Organization, World Health Organization, Geneva   +52 more
core   +3 more sources

Transaminases activity in the sand lizard’s serum under influence of industrial pollution

Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2009
Influence of the environmental pollution on the alanine aminotransferase and aspartate aminotransferase activity in the blood serum of the sand lizard has been studied. Aminotransferases (ALT and AST) are similar by the mechanism of action. These enzymes
O. Y. Klymenko, V. Y. Gasso
doaj   +1 more source

The cytosolic and mitochondrial aspartate aminotransferases from pig heart. A comparison of their primary structures, predicted secondary structures and some physical properties.

European Journal of Biochemistry, 1980
1. A primary structure is presented for mitochondrial aspartate aminotransferase from pig heart based on previously published results [Barra et al. (1977) FEBS Lett. 83, 241–244; Doonan et al. (1979) Ital. J. Biochem. 28, 441–455; Barra et al.
D. Barra, F. Bossa, S. Doonan, H. Fahmy, G. Hughes, F. Martini, R. Petruzzelli, B. Wittmann-Liebold   +7 more
semanticscholar   +1 more source

Liver enzyme elevation in patients with ankylosing spondylitis treated with tumor necrosis factor inhibitors: a single-center historical cohort study [PDF]

The Korean Journal of Internal Medicine, 2020
Background/Aims Tumor necrosis factor inhibitors (TNFi) have been known to induce liver enzyme elevation, sometimes associated with viral reactivation or toxic hepatitis.
Su Jin Choi, Ji Seon Oh, Seokchan Hong, Chang-Keun Lee, Bin Yoo, Yong-Gil Kim   +5 more
doaj   +1 more source

Aminotransferases During Treatment Predict Long-Term Survival in Patients With Autoimmune Hepatitis Type 1:A Landmark Analysis [PDF]

, 2021
Background & Aims: Biochemical remission, important treatment goal in autoimmune hepatitis (AIH), has been associated with better long-term survival.
, Baven-Pronk, Martine, Biewenga, Maaike, Colle, Isabelle, Putter, Hein, Schouten, Jeoffrey, Sermon, Filip, van den Berg, Aad, van der Meer, Adriaan, van Hoek, Bart, Van Steenkiste, Christophe, van Vlierberghe, Hans, Verhelst, Xavier   +12 more
core   +5 more sources