Results 141 to 150 of about 172,803 (295)

Traceability of values for catalytic activity concentration of enzymes: a Certified Reference Material for aspartate transaminase on behalf of the IFCC Committee on Reference Systems for Enzymes

, 2010
Background: A new reference material for the liver enzyme aspartate transaminase (AST) (L-aspartate: 2-oxoglutarateaminotransferase, EC 2.6.1.1), also called aspartate aminotransferase (ASAT), has been developed under the code ERM-AD457/IFCC.
Shigeru Ueda, Paul F H Franck, Hendrik Emons, Poul J Jørgensen, Rainer Klauke, Joseph Henny, Steffen Bossert-Reuther, Jean-Marc Lessinger, Daniel Mazziotta, Mauro Panteghini, F Javier Gella, Brigitte Toussaint, Georges Férard, Carlo A Ferrero, Heinz G Schimmel, Gerhard Schumann, Ferruccio Ceriotti, Francesca Canalias   +17 more
core  

A novel online calculator based on albumin-bilirubin and aspartate transaminase-to-platelet ratio index for predicting postoperative morbidity following hepatectomy for hepatocellular carcinoma. [PDF]

Ann Transl Med, 2020
Sun LY, Zhu H, Diao YK, Xing H, Liang L, Li J, Zhou YH, Gu WM, Chen TH, Zeng YY, Pawlik TM, Lau WY, Li C, Shen F, Zhang CW, Yang T.   +15 more
europepmc   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Glutamic-Aspartic Transaminase

Journal of Biological Chemistry, 1965
W. Terry Jenkins, R.T. Taylor
openaire   +2 more sources

Effect of l-ornithine l-aspartate against thioacetamide-induced hepatic damage in rats

, 2011
Objective: To investigate the hepatoprotective activity of L-ornithine-L-aspartate against thioacetamide (TAA)-induced hepataopathy in rats. Materials and Methods: The hepatoprotective activity of L-ornithine-L-aspartate (OA) at a dose of 2 g/kg, p.o ...
Pal, S. N., Akhtar, M., Najmi, Abul K., Aqil, M., Pillai, K. K., Sharma, M.   +5 more
core  

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

Advanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo, Jin Yang, Mengjie An, Bingjie Lin, Tao Liu, Limin Zhang   +5 more
wiley   +1 more source

Prospective analysis of 44 consecutive liver transplants performed at a university hospital

Acta Cirúrgica Brasileira, 2013
PURPOSE: To analyze the intraoperative and immediate postoperative biochemical parameters of patients submitted to orthotopic liver transplantation. METHODS: Forty four consecutive orthotopic liver transplants performed from October 2009 to December 2010
Orlando Castro e Silva, Priscila Nejo, Nathalia Cardoso, Enio David Mente, Fernanda Fernandes Souza, Andreza Corrêa Teixeira, Thiago Freitas, Daniel Cagnolati   +7 more
doaj  

Clinical Significance of Pre-to-Postoperative Dynamics of Aspartate Transaminase/Alanine Transaminase Ratio in Predicting the Prognosis of Renal Cell Carcinoma after Surgical Treatment. [PDF]

Dis Markers, 2020
Kang M, Shin SJ, Sung HH, Jeon HG, Jeong BC, Jeon SS, Lee HM, Seo SI.   +7 more
europepmc   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Asymptomatic elevation of serum aminotransferase activity: stages of diagnostic search

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2014
The aim of review. To present algorithm of stepwise clinical and laboratoric testing of patients with long-term asymptomatic elevation of serum aminotransferase activity.Key points.
Yu. A. Tereshchenko, S. Yu. Tereshchenko
doaj