Results 221 to 230 of about 471,402 (314)

Clinical Efficacy of Standardized Care for Abdominal Drainage Tubes in the Treatment of Acute Appendicitis: A Single-Center Retrospective Cohort Study. [PDF]

Emerg Med Int
Lin J, Zhou Y, Xu Z, Shi W, Huang Y, Tong G, Cai F, Yang Q, Chen C.   +8 more
europepmc   +1 more source

A Hepatocyte‐to‐Stellate Cell Axis Couples Alternate‐Day Fasting to Liver Fibrosis Resolution via ATG7 S‐Nitrosylation

Advanced Science, EarlyView.
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang, Mengqi Zeng, Cunxiao Sun, Yuhan Gou, Zhaode Feng, Weiqiang Lv, Chaoying Yan, Hansen Wu, Pengfei Zhang, Jie Xu, Ke Cao, Hao Li, Mingge Ding, Zhongbo Liu, Xing Zhang, Jiankang Liu, Xuan Zou, Zhihui Feng   +17 more
wiley   +1 more source

Protective Effects of L-Carnitine Supplement Combined with Interval Training on Kidney and Liver Function among Overweight and Obese Individuals. [PDF]

Int J Prev Med
Samsudin N, Ahmad NS, Ooi FK, Kadir AA, Kassim NK.   +4 more
europepmc   +1 more source

Correlations of Complete Blood Count with Alanine and Aspartate Transaminase in Chinese Subjects and Prediction Based on Back-Propagation Artificial Neural Network (BP-ANN). [PDF]

Med Sci Monit, 2017
Yu J, Pan Q, Yang J, Zhu C, Jin L, Hao G, Shi X, Cao H, Lin F.   +8 more
europepmc   +1 more source

Puerarin‑Loaded pH‑Responsive ZIF‑90 Nanoparticles Ameliorate Osteoporosis via Enhancing H3K18 Lactylation and Suppressing Aberrant Osteoclast Activation

Advanced Science, EarlyView.
Schematic illustration of the mechanism by which ZIF‐90@PU alleviates osteoporosis via H3K18la‐mediated NFATc1 pathway suppression. ABSTRACT Osteoporosis is characterized by dysregulated osteoclast activity, leading to excessive bone resorption and structural damage.
Jiajia Lu, Yue Xi, Sheng Wang, Ye Chen, Jiajie Yang, Xiaojian Shi   +5 more
wiley   +1 more source

Recurrent Cholestatic Jaundice in a Young Indian Adult: A Clinical Diagnosis of Benign Recurrent Intrahepatic Cholestasis. [PDF]

Cureus
Panda SS, Panda S, Jujharsingh A, Patra V.   +3 more
europepmc   +1 more source

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan, Andi Ma, Yiqiong Zhang, Minghao Zhang, Yifeng Lin, Xiaoling Zhang, Hongjun Li, Weidong Han   +7 more
wiley   +1 more source

Diagnostic performance of HScore for macrophage activation syndrome complicating Still's disease in adults: a multicentre case-control study. [PDF]

Rheumatology (Oxford)
Shiga T, Nozaki Y, Tsuchimoto S, Yamazawa H, Ashida C, Tomita D, Itami T, Hino S, Sugiyama M, Morita Y, Kinoshita K, Rai S.   +11 more
europepmc   +1 more source

Compound Abrus cantoniensis Extract Alleviates AFB1‐Induced Liver Injury by Regulating PI3K‐AKT Pathway and Gut Microbiota/Butyrate Metabolism

Advanced Science, EarlyView.
ACCE has a good alleviating effect on AFB1‐induced liver injury, and this alleviating effect is related to the PI3K‐AKT pathway regulated by ACCE and the butyrate metabolism of gut microbiota. ABSTRACT Aflatoxin B1 (AFB1) is a potent hepatotoxin commonly ingested through contaminated food. Abrus cantoniensis Hance, a traditional Chinese medicinal herb,
Hongjie Hu, Ming cheng, Shiqi Zheng, Huixin Liu, Xiaofang Wei, Wenwen Yang, Hongchun Yang, Liuyang Yuan, Li Jiang, Jie Chen, Linglong Zhao, Yanchao Guo, Hongbin Si   +12 more
wiley   +1 more source

Diffuse Large B-Cell Lymphoma Masquerading as Cholangiocarcinoma in a Young Adult. [PDF]

ACG Case Rep J
Gil-Lopez F, Lukens FJ, Paz-Fumagalli R, Moustafa MA, Majeed U, Guo R, Morales MC, Riley G, Mousa OY.   +8 more
europepmc   +1 more source