Results 21 to 30 of about 79,697 (280)

Tolvaptan-induced isolated elevation of bilirubin in a patient with Gilbert syndrome

SAGE Open Medical Case Reports, 2023
Tolvaptan is the current standard of treatment for autosomal dominant polycystic kidney disease. It operates by acting on V2 receptors and blocks vasopressin interactions, causing a reduction in the rate of renal cyst growth and preserving kidney ...
Matthew Nguyen, Beshoy T Yanny, Tai LD Truong, Hongyu Zhao, Ramy Hanna   +4 more
doaj   +1 more source

Cadmium chloride treatment of rats significantly impairs membrane integrity of mesenchymal stem cells via electrolyte imbalance and lipid peroxidation, a possible explanation of Cd related osteoporosis [PDF]

Iranian Journal of Basic Medical Sciences, 2017
Objective(s): Bone marrow mesenchymal stem cells (MSCs) play an important role in bone health. Cadmium causes osteoporosis, but the exact mechanisms of its effect on MSCs are not known.
Mohammad Husein Abnosi, Someyeh Golami
doaj   +1 more source

Prognostic Potential of Liver Enzymes in Patients With COVID-19 at the Leishenshan Hospital in Wuhan

Frontiers in Cellular and Infection Microbiology, 2021
BackgroundCoronavirus disease 2019 (COVID-19) has evolved into a pandemic. We hypothesized that biochemical indicators of liver function may help determine the prognosis of COVID-19 patients.MethodsPatient information was collected from the Wuhan ...
Zeming Liu, Di Hu, Jinpeng Li, Qing Xia, Yan Gong, Zhengwei Li, Qian Wu, Meilin Yi, Yihui Huang, Meng Wu, Liang Guo, Xiaohui Wu   +11 more
doaj   +1 more source

Association of Alanine Transaminase and Aspartate Aminotransferase/Alanine Transaminase Ratio with Type 2 Diabetes and Metabolic Syndrome in the Elderly [PDF]

Zhongguo quanke yixue, 2023
Background Serum alanine transaminase (ALT) and aspartate aminotransferase (AST) are common liver enzymes, but there are few studies on the correlation of these enzymes with the prevalence of type 2 diabetes mellitus (T2DM) and metabolic syndrome (MS ...
ZHOU Xiaoqi, LIU Xinhui, ZHANG Wei, LI Changfeng, YAN Yaqiong
doaj   +1 more source

On the flexibility of the cellular amination network in E coli

eLife, 2022
Ammonium (NH4+) is essential to generate the nitrogenous building blocks of life. It gets assimilated via the canonical biosynthetic routes to glutamate and is further distributed throughout metabolism via a network of transaminases.
Helena Schulz-Mirbach, Alexandra Müller, Tong Wu, Pascal Pfister, Selçuk Aslan, Lennart Schada von Borzyskowski, Tobias J Erb, Arren Bar-Even, Steffen N Lindner   +8 more
doaj   +1 more source

Interaction of difluoro-oxaloacetate with aspartate transaminase [PDF]

Biochemical Journal, 1977
Diffluoro-oxaloacetate behaves as a competitive inhibitor of 2-oxoglutarate and as an uncompetitive inhibitor with respect to aspartate in steady-state kinetic experiments with cytoplasmic aspartate transaminase. In the presence of high concentrations of aspartate transaminase, difluoro-oxaloacetate is slowly transaminated to difluoro-aspartate ...
Geoffrey D. Smith, P A Briley, Robert Eisenthal, Roger Harrison   +3 more
openaire   +3 more sources

Caracterização de variedades de batata doce (Ipomoea batatas L.) através de descritores morfológicos e isoenzimáticos Morphological and isoenzymatic characterization of sweet potato (Ipomoea batatas L.)

Ciência Rural, 2000
Ocorre grande variabilidade no germoplasma de batata-doce disponível no Rio Grande do Sul, mas nem todas populações podem ser caracterizadas através de aspectos morfológicos, havendo necessidade de recorrer a outros métodos, como análise de isoenzimas ...
Eliane Augustin, Alseny Garcia, Beatriz Helena Gomes Rocha   +2 more
doaj   +1 more source

Liver Dysfunction in Hypothyroid Non-Pregnant Women

Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College, 2018
Objective: To evaluate the effects of under secretion of thyroid hormones and its  relation  with  liver markers i.e. alanine transaminase (ALT) and aspartate transaminase (AST) in non-pregnant women.
Mohammad Yousaf, Zahoor Ahmad
doaj   +1 more source

Fontan‐Associated Liver Disease: Spectrum of Disease in Children and Adolescents

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Information is evolving on liver disease in pediatric patients with Fontan physiology. The purpose of this investigation is to evaluate the spectrum of liver disease in a pediatric population of patients with Fontan physiology and evaluate ...
Steven L. Rathgeber, Orlee R. Guttman, Anna F. Lee, Christine Voss, Nicole M. Hemphill, Richard A. Schreiber, Kevin C. Harris   +6 more
doaj   +1 more source

Effects of running speeds on some markers of muscular tissues and synovial fluid of Iraqi Arabian Horses

The Iraqi Journal of Veterinary Medicine, 2018
Arabian horses are regarded as the most famous breed for speed for long distances due to their genetic superiority. The aims of the study were to focus on the effect of different running speeds on the muscular tissues (Myoglobin, creatine kinase ...
Amir I. Towfik
doaj   +1 more source