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Core–shell nanogel of PEG–poly(aspartic acid) and its pH-responsive release of rh-insulin

, 2013
A new synthesis approach for the preparation of pH-responsive nanogels via core hydrolysis of cross-linked polymer micelles is proposed. The core–shell nanogels of poly(ethylene glycol)–poly(aspartic acid) exhibited a pH-responsive swelling behavior ...
Cw Park, Hm Yang, H. Lee, Jdk Kim
semanticscholar   +1 more source

SYNTHESIS OF ASPARTIC ACID BY LACTOBACILLUS ARABINOSUS

Canadian Journal of Microbiology, 1957
Lactobacillus arabinosus was grown on a complex synthetic medium and the synthesis of aspartic acid studied using the tracer compounds carbon dioxide-C14, glucose-6-C14, glucose-2-C14, or ammonium chloride-N15. The β-carboxyl carbon of aspartic acid was derived to a major extent or solely from carbon dioxide-C14and no radioactivity was found in the α ...
openaire   +5 more sources

Racemization of aspartic acid in human proteins

Ageing Research Reviews, 2002
Aspartic acid racemization (AAR) represents one of the major types of non-enzymatic covalent modification that leads to an age-dependent accumulation of abnormal protein in numerous human tissues. In vivo racemization is an autonomic process during the "natural" ageing of proteins, and correlates with the age of long-lived proteins.
Matthew J. Collins, Stefanie Ritz-Timme
openaire   +3 more sources

Six conformers of neutral aspartic acid identified in the gas phase.

Physical Chemistry, Chemical Physics - PCCP, 2010
The multiconformational landscape of the proteogenic amino acid aspartic acid, the simplest amino acid with two carboxylic groups, has been explored for the first time in the gas phase. Solid aspartic acid (m.p.
M. Sanz   +2 more
semanticscholar   +1 more source

Enzymic Deamination of Aspartic Acid

Nature, 1938
FROM the cell-free solution of B. fluorescens liquefaciens, which has a powerful aspartase effect1, we have isolated aspartase by adding acetic acid up to pH 4.6 at 0° C. The precipitate thereby formed (precipitation begins at pH 4.8) gives, when rapidly filtered and dissolved in M/15 phosphate buffer (pH 7), a solution which possesses considerable ...
Artturi I. Virtanen, Jorma Erkama
openaire   +2 more sources

Refinement of DL-aspartic acid [PDF]

open access: possibleActa Crystallographica Section B Structural Crystallography and Crystal Chemistry, 1973
Crystals of DL-aspartic acid (C4NO4H7) were grown at room temperature from an aqueous solution of the commercially available sample. The crystals be- long to the monoclinic system with cell dimensions a= 18.947+0.002, b= 7.433 + 0.001, c=9.184 + 0.001 A and fl=123.75+0-02 °. The systematic absences are: hkl, h + k = 2n + 1 and hOl, 1= 2n + 1. The space
openaire   +1 more source

Aspartic-Acid-Assisted Hydrothermal Growth and Properties of Magnetite Octahedrons

, 2010
A biomolecule-assisted hydrothermal route to the fabrication of magnetite (Fe3O4) with uniform microsized and regular octahedral morphology has been successfully developed by use of toxic-free aspartic acid as reducing reagent and FeCl3·6H2O as iron ...
Xiao-Fei Qu   +3 more
semanticscholar   +1 more source

2-(2-Pyridyl) benzimidazole based Co(II) complex as an efficient fluorescent probe for trace level determination of aspartic and glutamic acid in aqueous solution: a displacement approach.

Organic and biomolecular chemistry, 2011
A weakly fluorescent cobalt(II) complex is synthesized using 2-(2-pyridyl)-benzimidazole (PBI) as a chelating fluorescent ligand and characterized by single crystal X-ray structure.
Sudipta Das   +5 more
semanticscholar   +1 more source

The Aspartic Acid Family of Amino Acids: Biosynthesis

2004
Aspartic acid can be synthesized by two different reactions, both of which involve a substrate that is a participant in the tricarboxylic acid cycle. It can be obtained by transamination of oxaloacetic acid with glutamic acid, whose biosynthesis will be examined later: $$ \begin{array}{l}\kern6.84em \\ {}\begin{array}{c}\hfill \mathrm{COOH}-\mathrm ...
openaire   +2 more sources

L-ASPARTIC ACID FORMATION PROM N-ACETYL-L-ASPARTIC ACID IN THE BRAIN

Psychiatry and Clinical Neurosciences, 1961
Summary 1. Radioactive L-aspartic acid was produced by incubating C i*-N-acetyl-L-aspartic acid with a mouse brain homogenate. 2. Glutathione and Co++ must co-exist to activate this reaction. However, the reaction could be performed more or less by using Fe++, Cu++, Ca++, and Zn*+ instead of Co*H. 3.
openaire   +3 more sources

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