Results 301 to 310 of about 5,196,013 (375)

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo   +5 more
wiley   +1 more source

Heterogeneity of Intratumoral Microbiota Within the Tumor Microenvironment and Relationship to Tumor Development

open access: yesMed Research, EarlyView.
Mutual shaping of tumor microbiota and TME. Intratumoral microbiota—comprising diverse bacteria, fungi, viruses, and intracellular organisms—play critical and dynamic roles in shaping the tumor microenvironment (TME). Their spatial and compositional diversity contributes to both intratumoral and intertumoral heterogeneity, influencing immune modulation
Zhifei Gao   +9 more
wiley   +1 more source

Targeting Histone H3K9 Methyltransferase G9a as a Potential Therapeutic Strategy for Neuropsychiatric Disorders

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar   +4 more
wiley   +1 more source

Occurrence and integrated control of major rice diseases in China

open access: yesNew Plant Protection, EarlyView.
Rice is constantly under threat from a variety of pathogens. This review highlights the major diseases affecting rice in China, including three fungal diseases, two bacterial diseases, two viral diseases, and one nematode. The review also proposes future directions for an integrated approach to control these significant rice diseases.
Ruyi Wang   +13 more
wiley   +1 more source

The TBXT rs2305089 SNP links the benign notochordal cell tumour and chordoma

open access: yesThe Journal of Pathology, EarlyView.
Abstract The aim of this research was to investigate the pathogenesis of the bone cancer chordoma and the role of the germline rs2305089 SNP in TBXT. Using medical imaging and genotyping studies, we observed that benign notochordal cell tumours (BNCTs) were associated with chordomas and with the variant rs2305089 A‐allele with enrichment of the AA ...
Inga Usher   +8 more
wiley   +1 more source

Partially Biobased Self‐Repairing Poly(Aspartic Ester Polyurea) Coatings

open access: yesPolymer Engineering &Science, EarlyView.
Sustainable self‐healing PAEU coatings, containing various amounts of disulfide derived from poly(aspartic esters) and biobased polyisocyanates, were created. ABSTRACT Poly(aspartic ester polyurea) (PAEU) coating systems, which feature an uncatalyzed and solventless reaction, have attracted attention as a more environmentally friendly, nonreactive ...
Sevilay Dural   +2 more
wiley   +1 more source

Glycoproteomics and Its Role in Understanding Bacterial O‐Linked Glycosylation

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Protein glycosylation is now recognized as a ubiquitous process observed in all domains of life. Within bacterial species, carbohydrates can be attached to multiple residues with glycosylation of serine, threonine, or tyrosine residues via their hydroxyl side chains referred to as O‐linked glycosylation.
Kristian I. Karlic   +2 more
wiley   +1 more source

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