Results 301 to 310 of about 5,130,397 (333)

Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme.

Journal of Clinical Oncology, 2008
PURPOSE Cilengitide, an inhibitor of alphavbeta3 and alphavbeta5 integrin receptors, demonstrated minimal toxicity and durable activity across a wide range of doses administered to adults with recurrent glioblastoma multiforme (GBM) in a prior phase I ...
D. Reardon, K. Fink, T. Mikkelsen, T. Cloughesy, A. O'Neill, S. Plotkin, M. Glantz, P. Ravin, J. Raizer, K. Rich, D. Schiff, W. Shapiro, S. Burdette-Radoux, E. Dropcho, S. M. Wittemer, J. Nippgen, M. Picard, L. Nabors   +17 more
semanticscholar   +1 more source

Aspartic-acid synthesis in C3 plants

Planta, 1991
In a previous study (Melzer and O'Leary, 1987, Plant Physiol. 84, 58-60), we used isotopic methods to show that a substantial fraction of protein-bound aspartic acid in tobacco is derived from anaplerotic synthesis via phosphoenolpyruvate (PEP) carboxylase.
Marion H. O'Leary, Eva Melzer
openaire   +3 more sources

生命的起源與天門冬氨酸在水中的結晶; The Origin of Life and the Crystallization of Aspartic Acid in Water

, 2010
The unusual molecular complexation of the enantiomers of aspartic acid in water was discovered and proven by a solubility test, solution freezing point, crystallization kinetics, and the incubation time change.
林育琨, Yu-Kun Lin
semanticscholar   +1 more source

Solubility of D-Aspartic Acid and L-Aspartic Acid in Aqueous Salt Solutions from (293 to 343) K

, 2010
The solubility of d-aspartic acid and l-aspartic acid in aqueous solutions of various molalities of sodium chloride and potassium chloride was measured by using a laser technique from (293 to 343) K at atmospheric pressure.
Jianhong Wang, Jidong Wang, Jisheng Liu, Shui Wang, J. Pei   +4 more
semanticscholar   +1 more source

Decarboxylation of Aspartic and Glutamic Acids

Nature, 1938
ACCORDING to our earlier reports1, the legume bacteria split off quantitatively one of the carboxyl groups from l-aspartic acid forming β-alanine, HO2C.CH2.CH(NH2).CO2H→HO2C.CH2.CH2NH2 + CO2. The reaction was at first accomplished only with living bacteria.
T. Laine, P. Rintala, Arttuhi I. Virtanen   +2 more
openaire   +2 more sources

Absorption, utilization, and safety of aspartic acid

Journal of Toxicology and Environmental Health, 1976
The dicarboxylic amino acids, asparate and glutamate, occupy unique positions in intermediary metabolism, particularly in the mitochondria, where they play important roles in nitrogen and energy metabolism. Administration of large quantities of glutamate and asparate to the newborn mouse produces a variety of neurotoxic effects, the most marked of ...
openaire   +3 more sources

Rate of Aspartic Acid Racemization in Bone

The American Journal of Forensic Medicine and Pathology, 1998
There are no reports on rates of amino acid racemization in bones. To investigate the possibility of estimating age by evaluating amino acid residue racemization in human bones, a heating experiment was performed and the rate of aspartic acid racemization was determined using the Arrhenius equation.
openaire   +3 more sources

ASPARTIC ACID AND CANCER

The Lancet, 1968
B. Szende, E. Tyihák
openaire   +3 more sources

Stereospecificity in the chelation of aspartic acid

Journal of the American Chemical Society, 1967
J I Legg, D W Cooke
openaire   +3 more sources

[28] Cleavage at aspartic acid

1967
Publisher Summary This chapter describes the principle, procedures, and results of protein cleavage at peptide bonds linking aspartic acid or asparagine in the peptide chain. Dilute acid is used at a concentration just sufficient to maintain the β -carboxyl group of aspartic acid residues in the undissociated state. In this way aspartic acid peptide
openaire   +2 more sources