Results 61 to 70 of about 43,515 (179)

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

An Overview of West African Traditional Soft Cheese: Processing, Safety, and Quality Characteristics

Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 6, November 2025.
ABSTRACT West African soft cheese (WASC) is widely consumed and nutritionally valuable across West Africa. It also sustains livelihoods, particularly among Fulani households, by providing regular income for women and strengthens household food security and autonomy. However, concerns persist about its safety and quality.
Mahounakpon Wilfried Tossou, Matthew Atongbiik Achaglinkame, Linda Dari, Carole Nadia Adjouavi Sossa‐Vihotogbé, Zsanett Bodor, Daniel Mörlein   +5 more
wiley   +1 more source

Prorenin in Hepatic Stellate Cell Extracellular Vesicles Induces Platelet‐Dependent Thrombin Formation and Release of Profibrotic TGF‐β

The FASEB Journal, Volume 39, Issue 20, 31 October 2025.
Platelets interact with extracellular vesicles shed by hepatic stellate cells to activate both cell types. Extracellular vesicles shed by activated hepatic stellate cells contain inactive prorenin. HSC‐EV interact with quiescent platelets to non‐proteolytically activate ligated prorenin.
Rui Chen, Emily Huang, Xianfang Wu, Megan R. McMullen, Xianjia Wang, Laura E. Nagy, Ge Jin, Scott J. Cameron, Thomas M. McIntyre   +8 more
wiley   +1 more source

Aplicación de altas presiones hidrostáticas y enzimas proteolíticas en mostos para mejorar la estabilidad proteica de los vinos blancos [PDF]

, 2015
Actualmente se están buscando alternativas al uso de la bentonita como agente clarificante para vinos blancos, puesto que afecta a la características organolépticas de estos.
Juan Ovejero, Sara
core  

The Concise Guide to PHARMACOLOGY 2015/16:Enzymes [PDF]

, 2015
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org),
Aldrich, R, Alexander, SPH, Attali, B, Back, M, Barnes, NM, Bathgate, R, Beart, PM, Becirovic, E, Benson, HE, Biel, M, Birdsall, NJ, Boison, D, Brauner-Osborne, H, Broeer, S, Bryant, C, Burnstock, G, Burris, T, Cain, D, Calo, G, Chan, SL, Chandy, KG, Chiang, N, Christakos, S, Christopoulos, A, Chun, JJ, Chung, J-J, Clapham, DE, Connor, MA, Coons, L, Cox, HM, Dautzenberg, FM, Davies, JA, Dent, G, Douglas, SD, Dubocovich, ML, Edwards, DP, Fabbro, D, Faccenda, E, Farndale, R, Fong, TM, Forrest, D, Fowler, CJ, Fuller, P, Gainetdinov, RR, Gershengorn, MA, Goldin, A, Goldstein, SAN, Grimm, SL, Grissmer, S, Gundlach, AL, Hagenbuch, B, Hammond, JR, Hancox, JC, Hartig, S, Hauger, RL, Hay, DL, Hebert, T, Hollenberg, AN, Holliday, ND, Hoyer, D, Ijzerman, AP, Inui, KI, Ishii, S, Jacobson, KA, Jan, LY, Jarvis, GE, Jensen, R, Jetten, A, Jockers, R, Kaczmarek, LK, Kanai, Y, Kang, HS, Karnik, S, Kelly, E, Kerr, ID, Korach, KS, Lange, CA, Larhammar, D, Leeb-Lundberg, F, Leurs, R, Lolait, SJ, Macewan, D, Maguire, JJ, Marrion, N, May, JM, Mazella, J, McArdle, CA, McDonnell, DP, Michel, MC, Miller, LJ, Mitolo, V, Monie, T, Monk, PN, Mouillac, B, Murphy, PM, Nahon, J-L, Nerbonne, J, Nichols, CG, Norel, X, Oakley, R, Offermanns, S, Palmer, LG, Panaro, MA, Pawson, AJ, Perez-Reyes, E, Pertwee, RG, Peters, JA, Pike, JW, Pin, JP, Pintor, S, Plant, LD, Poyner, DR, Prossnitz, ER, Pyne, S, Ren, D, Richer, JK, Rondard, P, Ross, RA, Sackin, H, Safi, R, Sanguinetti, MC, Sartorius, CA, Segaloff, DL, Sharman, JL, Sladek, FM, Southan, C, Stewart, G, Stoddart, LA, Striessnig, J, Summers, RJ, Takeda, Y, Tetel, M, Toll, L, Trimmer, JS, Tsai, M-J, Tsai, SY, Tucker, S, Usdin, TB, Vilargada, J-P, Vore, M, Ward, DT, Waxman, SG, Webb, P, Wei, AD, Weigel, N, Willars, GB, Winrow, C, Wong, SS, Wulff, H, Ye, RD, Young, M, Zajac, J-M   +151 more
core   +4 more sources

Structural and Functional Variations of Enzymes Indicate Latitudinal Adaptations of Subarctic and Arctic Sea Urchins

Ecology and Evolution, Volume 15, Issue 10, October 2025.
Rapid warming in Arctic fjords challenges cold‐adapted benthic species, such as sea urchins of the genus Strongylocentrotus, key grazers on kelp forests. By comparing Arctic and Subarctic populations, we identified genetic and enzymatic differences in Arctic sea urchins, suggesting enhanced metabolic efficiency at low temperatures and potential for ...
Marie Koch, Sylke Wohlrab, Lars Harms, Reinhard Saborowski   +3 more
wiley   +1 more source

Spontaneous Isomerization of Long-Lived Proteins Provides a Molecular Mechanism for the Lysosomal Failure Observed in Alzheimer's Disease. [PDF]

, 2019
Proteinaceous aggregation is a well-known observable in Alzheimer's disease (AD), but failure and storage of lysosomal bodies within neurons is equally ubiquitous and actually precedes bulk accumulation of extracellular amyloid plaque. In fact, AD shares
Augello, Catherine, Coburn, Emily, Ford, Byron D, Julian, Ryan R, Kang, Amrik S, Lambeth, Tyler R, Noll, Jessica, Riggs, Dylan L, Talbert, Lance E, Tang, Jin   +9 more
core   +1 more source

Collagen processing and cuticle formation is catalysed by the astacin metalloprotease DPY-31 in free-living and parasitic nematodes [PDF]

, 2010
The exoskeleton or cuticle performs many key roles in the development and survival of all nematodes. This structure is predominantly collagenous in nature and requires numerous enzymes to properly fold, modify, process and cross-link these essential ...
Albertson, Antony P. Page, Bastin, Bird, Blaxter, Blelloch, Davis, Gallego, Gamble, Gamble, Ge, Gillian McCormack, Gillian Stepek, Hartigan, Hawdon, Hill, Hishida, Jones, Keskiaho, Kessler, Mitreva, Moerman, Möhrlen, Nelson, Novelli, Novelli, Opperman, Page, Redmond, Shamansky, Stepek, Studier, Stöcker, Stöcker, Suzuki, Thein, Van der Keyl, Williamson   +37 more
core   +1 more source

Hydrogels Based on Poly(aspartic acid): Synthesis and Applications

Frontiers in Chemistry, 2019
This review presents an overview on the recent progress in the synthesis, crosslinking, interpenetrating networks, and applications of poly(aspartic acid) (PASP)-based hydrogels.
H. Adelnia, I. Blakey, P. Little, H. Ta
semanticscholar   +1 more source

Employing complementary fractionation‐based N‐terminomics approaches enhances the identification of legumain cleavage events in naïve and inflamed colon tissue

Protein Science, Volume 34, Issue 10, October 2025.
Abstract The mammalian lysosomal protease legumain is often dysregulated in pathophysiological conditions including inflammation, neurodegeneration, and cancer, yet its proteolytic targets are poorly defined. To profile protease substrates, degradomics techniques typically employ enrichment strategies to select for sub‐stoichiometric and low‐abundance ...
Alexander R. Ziegler, Benjamin L. Parker, Nichollas E. Scott, Laura E. Edgington‐Mitchell   +3 more
wiley   +1 more source