Results 111 to 120 of about 64,761 (239)

Attainment of therapeutic posaconazole serum levels during co-administration with rifampicin

Journal of Global Antimicrobial Resistance, 2020
Nicholas Power, Fiona Lynch, David W. Denning, Rohit Bazaz   +3 more
doaj   +1 more source

Semiinvasive Aspergillosis: A Diagnosis to Consider in a Seemingly Immunocompetent Patient with a Pulmonary Nodule, Haemoptysis and Structural Lung Disease

Acta Medica, 2009
Semiinvasive pulmonary aspergillosis is an indolent form of pulmonary aspergillosis, which is seen mainly in patients who are mildly immunocompromised with underlying chronic lung diseases.
Francisco José Fernández-Fernández, Marcelino del Castillo-Fraile, María del Mar Used-Aznar   +2 more
doaj   +1 more source

Population Pharmacokinetic Model Assessment of the Effects of Body Weight on Risk of Drug–Drug Interactions After Posaconazole Discontinuation

Clinical and Translational Science, Volume 19, Issue 4, April 2026.
ABSTRACT Posaconazole is a broad‐spectrum triazole antifungal agent indicated for the prophylaxis and treatment of invasive fungal infections. Posaconazole pharmacokinetics and drug–drug interactions (DDIs), due to cytochrome P450 3A4 (CYP3A4) inhibition, have been previously characterized.
Rebecca E. Wrishko, Thomas J. Bateman, Matthew G. Johnson, Prajakti A. Kothare   +3 more
wiley   +1 more source

Improvements in Real‐World Survival in the Setting of a Recent Paradigm Shift in Acute Myeloid Leukemia Treatment

European Journal of Haematology, Volume 116, Issue 4, Page 416-424, April 2026.
ABSTRACT Therapeutic options for newly diagnosed (ND) acute myeloid leukemia (AML) have increased in recent years, leading to a shift in the treatment paradigm from conventional, intensive chemotherapy toward targeted and less intensive therapy. Since 2017, there has been a surge in FDA approvals for novel therapies, including small molecule inhibitors
Thuy N. Ho, Patrick Willard, Graeme F. Murray, Li Liu, Nolan Wages, Hyun Lee, Keri R. Maher   +6 more
wiley   +1 more source

Evaluation of the Diagnostic Accuracy of the Quantitative Point‐of‐Care SD Biosensor Standard G6PD Test for Assessment of G6PD Deficiency in Infectious Diseases

International Journal of Laboratory Hematology, Volume 48, Issue 2, Page 440-446, April 2026.
ABSTRACT Background G6PD deficiency affects about 500 million people worldwide and is prevalent in many malaria‐endemic settings. People with G6PD deficiency are at risk of hemolysis when exposed to certain medications, including 8‐aminoquinoline drugs used to treat Plasmodium vivax malaria.
Flavia Regina Medeiros da Silva, Alexandre Gomes Vizzoni, Daniela Mendes‐de‐Almeida, Joanna Bokel, Raquel de Vasconcellos Carvalhaes de Oliveira, André Machado Siqueira, Yasmine Rangel Vieira, Simone da Costa Cruz Silva   +7 more
wiley   +1 more source

Seroprevalence Screening of Chronic Aspergillus Infection in a Post‐Tuberculosis Cohort in Senegal: A Cross‐Sectional Study Comparing ELISA and Rapid Diagnostic Tests

Mycoses, Volume 69, Issue 4, April 2026.
ABSTRACT Background Chronic pulmonary aspergillosis (CPA) is a significant, yet often overlooked, sequela of pulmonary tuberculosis (TB), particularly in resource‐limited settings. Data on the seroprevalence of Aspergillus infection in Senegal is absent, and diagnostic capacity is limited. This study aimed to determine the seroprevalence of Aspergillus‐
Touré Mariama, Ndiaye Ibrahima Mbaye, Sow Djiby, Diallo Mamadou Alpha, Diongue Khadim, Seck Mame Cheikh, Ndiaye Mouhamadou, Ndiaye Daouda, Ndiaye Faly Diop, Fortes Louise, Denning David, Badiane Aida Sadikh   +11 more
wiley   +1 more source

Pre-existing invasive fungal infection is not a contraindication for allogeneic HSCT for patients with hematologic malignancies: a CIBMTR study. [PDF]

, 2017
Patients with prior invasive fungal infection (IFI) increasingly proceed to allogeneic hematopoietic cell transplantation (HSCT). However, little is known about the impact of prior IFI on survival.
Aljurf, M, Auletta, JJ, Battiwalla, M, Boeckh, MJ, Brazauskas, R, Chen, M, Dvorak, CC, Gea-Banacloche, J, Geroge, B, Guinan, EC, Hale, GA, Lazarus, HM, Lee, J-W, Liesveld, JL, Lindemans, CA, Martino, R, Maziarz, RT, McLeod, AA, Ramanathan, M, Reddy, V, Riches, ML, Savani, BN, Smith, FO, Strasfeld, L, Taplitz, RA, Ustun, C, Wingard, JR   +26 more
core  

Diagnosis of Mucormycosis: Current Situation, Challenges and Future Prospects

Mycoses, Volume 69, Issue 4, April 2026.
ABSTRACT Mucormycosis, an aggressive fungal infection caused by members of the order Mucorales, progresses rapidly and is associated with high mortality, particularly in immunocompromised hosts such as patients with uncontrolled diabetes, transplant recipients or those with COVID‐19‐associated immunosuppression. Early diagnosis remains challenging with
Yixuan Qu, Yuling Xiao, Lina Liu, Junyan Qu   +3 more
wiley   +1 more source

A Novel Hyphal Suspension Approach for MIC Testing of Mould Fungi

Mycoses, Volume 69, Issue 4, April 2026.
ABSTRACT Background Filamentous fungi cause a wide range of superficial and invasive infections, and antifungal susceptibility assay is essential for guiding effective therapy. Standard broth microdilution methods rely on microconidia‐based inocula; however, many clinically important moulds produce insufficient microconidia due to intrinsic ...
Hailin Zheng, Dongmei Li, Naicen Ge, Huan Mei, Xiaofang Li, Weida Liu   +5 more
wiley   +1 more source

Pulmonary aspergillosis associated with antineutrophil cytoplasmic antibody-positive vasculitis involving skin and peripheral nerves

Journal of the Indian Academy of Geriatrics
Invasive pulmonary aspergillosis is the most common cause of invasive fungal infection. Vasculitis secondary to bacterial, fungal, viral, and parasitic infections is documented in the literature.
Abhijith Rajaram Rao, Mohamed Rishan, Prakruthi Jaladhar, Prabha Adhikari   +3 more
doaj   +1 more source