Results 61 to 70 of about 100,852 (314)

Risks of ventilator-associated pneumonia and invasive pulmonary aspergillosis in patients with viral acute respiratory distress syndrome related or not to Coronavirus 19 disease

Critical Care, 2020
Background Data on incidence of ventilator-associated pneumonia (VAP) and invasive pulmonary aspergillosis in patients with severe SARS-CoV-2 infection are limited.
K. Razazi, R. Arrestier, A. Haudebourg, Brice Benelli, G. Carteaux, J. Decousser, S. Fourati, P. Woerther, F. Schlemmer, A. Charles-Nelson, F. Botterel, N. de Prost, A. Mekontso Dessap   +12 more
semanticscholar   +1 more source

Solid‐State NMR Reveals Reorganization of the Aspergillus fumigatus Cell Wall Due to a Host‐Defence Peptide

Angewandte Chemie International Edition, EarlyView.
Understanding the mode of action is critical to develop new antifungal drugs. Solid‐state NMR was used to study the reorganization of the Aspergillus fumigatus cell wall by a host‐defence peptide. We identified specific polysaccharides and amino acids that are affected by the peptide.
Ajit Kumar Bishoyi, Jacq van Neer, Salima Bahri, Sophie Lorenz, Hans de Cock, Marc Baldus   +5 more
wiley   +1 more source

Incremental Healthcare Costs and Outpatient Antifungal Treatment of Patients with Aspergillosis in the United States

Journal of Health Economics and Outcomes Research, 2013
**Objectives:** To evaluate the total and outpatient economic burden of aspergillosis, and to describe the outpatient antifungal treatment of aspergillosis within a large, commercially-insured population in the United States. **Methods:** Adults with at
Emily Durden, Donna McMorrow, Paul Juneau, Robert Fowler, Paresh Chaudhari, David Horn   +5 more
doaj   +1 more source

Epidemiology of Aspergillosis in Cancer Patients in Taiwan

Infection and Drug Resistance, 2022
Chien-An Chen,1,2,* Chung-Han Ho,3– 5,* Yu-Cih Wu,3 Yi-Chen Chen,3 Jhi-Joung Wang,3 Kuang-Ming Liao6 1Division of Hepatogastroenterology, Department of Internal Medicine, Chi Mei Medical Center, Tainan, 71004, Taiwan; 2Division of Hospital ...
Chen CA, Ho CH, Wu YC, Chen YC, Wang JJ, Liao KM   +5 more
doaj  

Single dose pharmacodynamics of amphotericin B against Aspergillus species in an in vitro pharmacokinetic/pharmacodynamic model [PDF]

, 2013
Conventional MIC testing of amphotericin B results in narrow MIC ranges challenging the detection of resistant strains. In order to discern amphotericin B pharmacodynamics, the in vitro activity of amphotericin B was studied against Aspergillus isolates ...
Al-Saigh, Rafal, Aristea, Velegraki, Meletiadis, Joseph, Siafakas, Nikolaos, Siopi, Maria, Zerva, Loukia   +5 more
core   +1 more source

Metamizole induces voriconazole metabolism and results in subtherapeutic voriconazole concentrations

British Journal of Clinical Pharmacology, EarlyView.
Aims Voriconazole is extensively metabolized via cytochrome P450 (CYP) enzymes, predominantly CYP2C19 and CYP3A4. Drugs influencing the activity or expression of CYP enzymes can cause clinically relevant changes in the metabolism and voriconazole exposure. Metamizole is known to induce CYP3A4 and CYP2C19.
Simone D. Baan, Daan J. Touw, Marjolijn N. Lub‐de Hooge, Thijs H. Oude Munnink   +3 more
wiley   +1 more source

Pulmonary Aspergillosis in Patients with Cystic Fibrosis in Russian Federation

Журнал инфектологии, 2018
The aim: to assess the incidence of various forms of pulmonary aspergillosis in patients with cystic fibrosis.Materials and methods. In 2014-2017 yy. in prospective study in  different regions of Russia were included 190 patients with cystic  fibrosis ...
Ya. I. Kozlova, Yu. V. Borzova, O. V. Shadrivova, I. E. Suslova, O. V. Aak, S. M. Ignat’eva, T. S. Bogomolova, V. A. Ponnaja, T. A. Stepanenko, A. V. Orlov, S. A. Krasovskiy, N. N. Klimko   +11 more
doaj   +1 more source

Microsatellite typing of avian clinical and environmental isolates of Aspergillus fumigatus [PDF]

, 2011
Aspergillosis is one of the most common causes of death in captive birds. Aspergillosis in birds is mainly caused by Aspergillus fumigatus, a ubiquitous and opportunistic saprophyte.
Beernaert, Lies, Dorrestein, Gerry M, Haesebrouck, Freddy, Klaassen, Corné HW, Martel, An, Pasmans, Frank, Van Waeyenberghe, Lieven, Vercammen, Francis, Verstappen, Frank   +8 more
core   +3 more sources

Artificial intelligence modelling of tyrosine kinase inhibitors at risk of malabsorption and bioavailability‐enhancing strategies

British Journal of Clinical Pharmacology, EarlyView.
Aims The study aims to predict and improve the absorption of tyrosine kinase inhibitors (TKIs) in patients with malabsorption issues, particularly those who have undergone bariatric surgery or are using proton‐pump inhibitors. The research involves 2 main components: the development of an artificial intelligence (AI) model to identify TKIs that are ...
Daan W. Huntjens, Olivier J. M. Béquignon, Stefanie D. Krens, Mark Löwenberg, Martine E. D. Chamuleau, Remco J. Molenaar, Anita M. G. Kramers, Marianne A. Kuijvenhoven, Imke H. Bartelink   +8 more
wiley   +1 more source

From phagocytosis to metaforosis: calcineurin's deadly role in innate processing of fungi [PDF]

, 2018
Data Availability: The authors confirm that all data underlying the findings are fully available without restriction. Raw data have been deposited in the Gene Expression Omnibus (GEO) (http://www.ncbi.nlm.nih.gov/geo/) under accession number GSE54810 ...
Armstrong-James, D, Bercusson, A, De Boer, L, Shah, A   +3 more
core   +11 more sources