Results 51 to 60 of about 45,302 (241)
Pulmonary Aspergillosis in Patients with Cystic Fibrosis in Russian Federation
The aim: to assess the incidence of various forms of pulmonary aspergillosis in patients with cystic fibrosis.Materials and methods. In 2014-2017 yy. in prospective study in different regions of Russia were included 190 patients with cystic fibrosis ...
Ya. I. Kozlova +11 more
doaj +1 more source
Aims Voriconazole is commonly used to prevent fungal infections after haematopoietic stem cell transplantation (HSCT). Although its metabolism is influenced by CYP2C19 genetics and inflammation, their combined effect is rarely considered in clinical practice, and integrated analyses remain limited.
Sylvia D. Klomp +6 more
wiley +1 more source
Treatment Of Invasive Aspergillosis [PDF]
Invasive aspergillosis (IA) is an infectious disease caused by Aspergillus species, is usually seen in patients with immune deficiency and has been associated with high mortality rate.
Mustafa DOĞAN +4 more
core
Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley +1 more source
Invasive aspergillosis in an immunocompetent patient with fever and a cardiac mass
Invasive aspergillosis is an often fatal disease that usually occurs in immunocompromised patients. We report a case of invasive aspergillosis presenting as a febrile respiratory infection with a cardiac mass in an immunocompetent patient.
Matthew LaBarbera, Lester B. Jacobson
doaj +1 more source
Immunotherapy of aspergillosis [PDF]
Management of invasive aspergillosis in high-risk patients remains challenging. There is an increasing demand for novel therapeutic strategies aimed at enhancing or restoring antifungal immunity in immunocompromised patients. In this regard, modulation of specific innate immune functions and vaccination are promising immunotherapeutic strategies ...
Carvalho A. +3 more
openaire +4 more sources
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama +16 more
wiley +1 more source
A model of cerebral aspergillosis in non-immunosuppressed nursing rats [PDF]
Central nervous system aspergillosis is an often fatal complication of invasive Aspergillus infection. Relevant disease models are needed to study the pathophysiology of cerebral aspergillosis and to develop novel therapeutic approaches.
Stefan Zimmerli +5 more
core +1 more source
Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton +19 more
wiley +1 more source
CLINICAL OBSERVATION OF CHRONIC ASPERGILLOSIS IN A PATIENT WITH SPINAL BLOOD CIRCULATION DISORDER
Subject of research. Study of the influence of pathogenic factors and predisposing conditions on the development of aspergillosis of the central nervous system. Purpose of research – demonstration of a clinical case of chronic aspergillosis in a patient
Марина Анатольевна Пеганова +4 more
doaj

