Studies on the release of neutrophil extracellular traps and IFN-γ as part of the innate immune response to Aspergillus fumigatus and on the fungal stress response via the hybrid sensor kinase TcsC [PDF]
, 2012 Aspergillus fumigatus is a saprophytic mold that naturally inhabits the soil. Asexual reproduction yields hardy conidia that circulate in the air and are inhaled daily by humans.
McCormick, Allison
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Quantification of voriconazole in plasma by liquid chromatography-tandem mass spectrometry [PDF]
, 2005 A convenient liquid chromatography-tandem mass spectrometry method for the quantification of the triazole antifungal agent voriconazole in plasma samples is described. Fenbuconazole is used as an internal standard.
Boyd +16 more
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International Journal of Clinical Practice, 1993 SUMMARY A fatal case of cerebral aspergillosis is described in a patient with bronchial asthma maintained on beclomethasone inhalation therapy.
H, al Soub, S, Iskander, A K, Uwaydah
openaire +2 more sources
Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang +3 more
wiley +1 more source
Hidden Fungal Diversity of the Precious Mediterranean Red Coral Corallium rubrum
Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.This study reveals diverse cultivable fungi associated with the red coral Corallium rubrum, highlighting both potentially beneficial and pathogenic species. These findings emphasize the biotechnological relevance and ecological impact of coral‐associated fungi, especially as climate change may increase disease risks.
Camille Prioux +7 more
wiley +1 more source
Determination of itraconazole and hydroxyitraconazole in plasma by use of liquid chromatography-tandem mass spectrometry with on-line solid-phase extraction [PDF]
, 2003 In this paper a method for the simultaneous quantification of the anti-fungal drug itraconazole and its co-active metabolite hydroxyitraconazole in plasma employing liquid chromatography tandem-mass spectrometry and automated solid-phase extraction is ...
Schiel, Xaver +2 more
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Medical Mycology, 2000 Acute invasive aspergillosis (IA) is a devastating disease. Early diagnosis allowing an early treatment may improve the prognosis. However, this goal remains difficult to achieve. When diagnosis is confirmed it is often already too late. Galactomannan antigen detection and DNA detection are under clinical evaluation to improve early diagnosis and ...
Verweij, P.E. +6 more
openaire +4 more sources
Journal of Medical Virology, Volume 98, Issue 5, May 2026.ABSTRACT Torque teno virus (TTV) replication is tightly modulated by the host immune response. As such, TTV viremia has been investigated as a biomarker of immune competence for monitoring the risks of allograft rejection and opportunistic infections in solid organ transplant recipients.
Mahdi Ouafi +15 more
wiley +1 more source
Specific Antibodies to Recombinant Allergens of \u3cem\u3eAspergillus fumigatus\u3c/em\u3e in Cystic Fibrosis Patients with ABPA [PDF]
, 2006 Background Aspergillus fumigatus, a widely distributed fungus, has been implicated in causing life threatening infections as well as severe asthma and allergic diseases in man.
Bansal, Naveen K. +3 more
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Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis. [PDF]
, 2020 There are limited treatment options for immunosuppressed patients with lethal invasive fungal infections due to Fusarium and Scedosporium Manogepix (MGX; APX001A) is a novel antifungal that targets the conserved Gwt1 enzyme required for localization of ...
Alkhazraji, Sondus +8 more
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