Results 61 to 70 of about 45,302 (241)

Disseminated cerebral aspergillosis complicated by thrombotic microangiopathy

Medical Mycology Case Reports, 2019
Invasive aspergillosis (IA) is a serious condition that can affect almost any organ. Cerebral aspergillosis itself is rapidly fatal without treatment. We report a case of disseminated cerebral IA in a patient exposed to cyclophosphamide, rituximab and ...
Robynn Lester, Deirdre Church, Anshula Ambasta   +2 more
doaj   +1 more source

Remission in Global Airway Diseases: EUFOREA Consensus Paper

Allergy, EarlyView.
ABSTRACT The therapeutic goal in chronic airway diseases is shifting from symptom control to disease remission. Disease‐modifying therapies, including biologics and allergen immunotherapy, have made remission achievable in patients with severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), or allergic rhinitis (AR).
J. Christian Virchow, Xander Bertels, Vibeke Backer, Benjamin S. Bleier, Marco Caminati, Diego M. Conti, Eugenio De Corso, Mina Gaga, Valerie J. Lund, Corrado Pelaia, Anju T. Peters, Glenis K. Scadding, Martin Wagenmann, Riyad O. Al‐Lehebi, Guy G. Brusselle, Philippe Gevaert, Liam G. Heaney, Stella E. Lee, Florence Schleich, Frederik Trinkmann, Peter W. Hellings, Wytske J. Fokkens, Paola Rogliani   +22 more
wiley   +1 more source

Measuring the exosomal microRNA changes in hematology and oncology patients suffering by invasive aspergillosis

, 2023
This study aimed to compare the alterations on expression patterns of exosomal microRNAs between invasive aspergillosis patients and healthy controls.
Hossain, Syed Akib
core  

Pharmacodynamic Effects of Simulated Standard Doses of Antifungal Drugs against Aspergillus Species in a New In Vitro Pharmacokinetic/Pharmacodynamic Model [PDF]

, 2011
In conventional MIC tests, fungi are exposed to constant drug concentrations, whereas in vivo, fungi are exposed to changing drug concentrations.
Thomas J. Walsh, Emmanuel Roilides, Aristea Velegraki, Walsh, Thomas, Zerva, Loukia, Meletiadis, Joseph, Joseph Meletiadis, Roilides, Emmanuel, Rafal Al-Saigh, Velegraki, Aristea, Loukia Zerva, Al Saigh, Rafal   +11 more
core   +1 more source

Anticoagulation Strategies in Adults Undergoing Extracorporeal Membrane Oxygenation: A Systematic Review and Meta‐Analysis

Artificial Organs, EarlyView.
In this meta‐analysis of 2 775 adult ECMO patients from non‐randomized studies, direct thrombin inhibitors and low‐molecular‐weight heparins demonstrated a favorable efficacy and safety profile over unfractionated heparin. These findings suggest them to be effective alternatives to unfractionated heparin, underscoring the urgent need for randomized ...
Vincenz Scharner, Karoline Lenz, Harald Herkner, Nina Buchtele, Thomas Staudinger, Eva Schaden, Marion Wiegele, Johannes Gratz   +7 more
wiley   +1 more source

Pathogenesis and clinical features of chronic pulmonary aspergillosis – Is it possible to distinguish CNPA and CCPA clinically?

, 2014
Background: The pathogenesis of chronic pulmonary aspergillosis (CPA) including chronic necrotizing pulmonary aspergillosis (CNPA), chronic cavitary pulmonary aspergillosis (CCPA), and simple aspergilloma (SA) has been poorly investigated.
Kakeya, Hiroshi, Imamura, Yoshifumi, Miyazaki, Taiga, Takazono, Takahiro, Yanagihara, Katsunori, Nagayasu, Takeshi, Kohno, Shigeru, Tsukamoto, Misuzu, Nakamura, Shigeki, Izumikawa, Koichi, Hayashi, Tomayoshi, Kurihara, Shintaro, Tashiro, Takayoshi, Tashiro, Masato, Kosai, Kosuke, Morinaga, Yoshitomo   +15 more
core   +1 more source

Aspergillus felis in Patient with Chronic Granulomatous Disease

Emerging Infectious Diseases, 2019
We report a case of Aspergillus felis infection in a patient with chronic granulomatous disease who had overlapping features of invasive pulmonary aspergillosis and allergic bronchopulmonary aspergillosis.
Olivier Paccoud, Romain Guery, Sylvain Poirée, Grégory Jouvion, Marie Elisabeth Bougnoux, Emilie Catherinot, Olivier Hermine, Olivier Lortholary, Fanny Lanternier   +8 more
doaj   +1 more source

A Simple and Rapid Fungal DNA Isolation Assay Based on ZnO Nanoparticles for the Diagnosis of Invasive Aspergillosis

Micromachines, 2020
Invasive aspergillosis (IA) is an important cause of morbidity and mortality among immunocompromised people. Imaging and specimen tests used in the clinical diagnosis of aspergillosis with weak and indistinct defects leads to delay in the treatment of ...
Zhen Qiao, Huifang Liu, Geun Su Noh, Bonhan Koo, Qingshuang Zou, Kyusik Yun, Yoon Ok Jang, Sung-Han Kim, Yong Shin   +8 more
doaj   +1 more source

COVID‐19 complicated with chronic necrotizing pulmonary aspergillosis and aspergilloma progressing to fibrosing aspergillosis: A case report

Clinical Case Reports, 2022
Aspergillosis superinfections have been reported as acute complications of COVID‐19. We report a rare case of combined chronic necrotizing pulmonary aspergillosis, aspergilloma, and fibrosing aspergillosis in a 31‐year‐old woman with a history of COVID ...
Zamelina Angela Razafindrasoa, Kiady Ravahatra, Harison Michel Tiaray, Anjara Mihaja Nandimbiniaina, Finaritra Princy Parfait Andriamahenina, Sonia Marcelle Razafimpihanina, Diamondra Ombanjanahary Andriarimanga, Jocelyn Robert Rakotomizao, Joëlson Lovaniaina Rakotoson, Rondro Nirina Raharimanana   +9 more
doaj   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source