Results 71 to 80 of about 103,375 (340)

Disseminated cerebral aspergillosis complicated by thrombotic microangiopathy

open access: yesMedical Mycology Case Reports, 2019
Invasive aspergillosis (IA) is a serious condition that can affect almost any organ. Cerebral aspergillosis itself is rapidly fatal without treatment. We report a case of disseminated cerebral IA in a patient exposed to cyclophosphamide, rituximab and ...
Robynn Lester   +2 more
doaj   +1 more source

COVID‐19 complicated with chronic necrotizing pulmonary aspergillosis and aspergilloma progressing to fibrosing aspergillosis: A case report

open access: yesClinical Case Reports, 2022
Aspergillosis superinfections have been reported as acute complications of COVID‐19. We report a rare case of combined chronic necrotizing pulmonary aspergillosis, aspergilloma, and fibrosing aspergillosis in a 31‐year‐old woman with a history of COVID ...
Zamelina Angela Razafindrasoa   +9 more
doaj   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami   +2 more
wiley   +1 more source

Invasive aspergillosis in an immunocompetent patient with fever and a cardiac mass

open access: yesInfectious Disease Reports, 2011
Invasive aspergillosis is an often fatal disease that usually occurs in immunocompromised patients. We report a case of invasive aspergillosis presenting as a febrile respiratory infection with a cardiac mass in an immunocompetent patient.
Matthew LaBarbera, Lester B. Jacobson
doaj   +1 more source

A Simple and Rapid Fungal DNA Isolation Assay Based on ZnO Nanoparticles for the Diagnosis of Invasive Aspergillosis

open access: yesMicromachines, 2020
Invasive aspergillosis (IA) is an important cause of morbidity and mortality among immunocompromised people. Imaging and specimen tests used in the clinical diagnosis of aspergillosis with weak and indistinct defects leads to delay in the treatment of ...
Zhen Qiao   +8 more
doaj   +1 more source

CLINICAL OBSERVATION OF CHRONIC ASPERGILLOSIS IN A PATIENT WITH SPINAL BLOOD CIRCULATION DISORDER

open access: yesМедицина в Кузбассе, 2020
Subject of research. Study of the influence of pathogenic factors and predisposing conditions on the development of aspergillosis of the central nervous system. Purpose of research – demonstration of a clinical case of chronic aspergillosis in a patient
Марина Анатольевна Пеганова   +4 more
doaj  

Novel Clinical and Laboratorial Challenges in Aspergillosis

open access: yesMicroorganisms, 2022
In recent years, research in the areas of Aspergillus and aspergillosis has continued to advance rapidly, including advancements in genomics, immunological studies, clinical areas, and diagnostic areas.
Raquel Sabino, Cristina Veríssimo
doaj   +1 more source

Pulmonary Aspergillosis [PDF]

open access: yesSeminars in Respiratory and Critical Care Medicine, 2008
As the population of patients with prolonged neutropenia, those receiving hematopoietic stem cell transplantation or lung transplantation, or those with human immunodeficiency virus or acquired immunodeficiency syndrome continues to increase, the rising incidence of pulmonary aspergillosis is unlikely to diminish.
George R, Thompson, Thomas F, Patterson
openaire   +2 more sources

ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukemia and hematopoietic stem cell transplant patients

open access: yesHaematologica, 2016
The European Conference on Infections in Leukemia (ECIL) provides recommendations for diagnostic strategies and prophylactic, pre-emptive or targeted therapy strategies for various types of infection in patients with hematologic malignancies or ...
F. Tissot   +9 more
semanticscholar   +1 more source

Comparative Analysis of Isavuconazole DDIs With Other Azole Antifungal Drugs and PBPK Model‐Informed Dosing Recommendations for Anticancer Drugs

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Isavuconazole is a broad‐spectrum triazole approved for the treatment of invasive aspergillosis or mucormycosis in adults and children aged ≥ 1 year. Current prescribing information lacks guidance regarding the co‐administration of isavuconazole with anticancer drugs–limited by the availability of clinical drug–drug interaction (DDI) data in ...
Theunis C. Goosen   +6 more
wiley   +1 more source

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