Results 91 to 100 of about 405,824 (337)

Allergic Aspergillus Rhinosinusitis [PDF]

Journal of Fungi, 2016
Allergic fungal rhinosinusitis (AFRS) is a unique variety of chronic polypoid rhinosinusitis usually in atopic individuals, characterized by presence of eosinophilic mucin and fungal hyphae in paranasal sinuses without invasion into surrounding mucosa. It has emerged as an important disease involving a large population across the world with geographic ...
Arunaloke Chakrabarti, Harsimran Kaur
openaire   +4 more sources

Enhancing the β‐Oxidation‐Like Pathway for the Optimal Production of the Immunosuppressant Mycophenolic Acid

Advanced Science, EarlyView.
The most elaborate known example of β‐oxidation‐like pathway recruitment in fungi is reported, involving a 10‐step oxidative chain‐shortening cascade catalyzed by five dedicated enzymes to generate the pharmacophore of mycophenolic acid (MPA)—a novel clinical immunosuppressant. Our findings illustrate how nature repurposes catabolic enzymes for complex
Baoqiang Fan, Yinuo Liu, Lu‐ping Chi, Chaofan Yang, Shengying Li, Wei Zhang   +5 more
wiley   +1 more source

Germination of Aspergillus fumigatus inside avian respiratory macrophages is associated with cytotoxicity [PDF]

, 2012
Although aspergillosis is one of the most common diseases in captive birds, the pathogenesis of avian aspergillosis is poorly known. We studied the role of avian respiratory macrophages as a first line of defense against avian aspergillosis.
D'Herde, Katharina, Ducatelle, Richard, Favoreel, Herman, Haesebrouck, Freddy, Li, Shaoji, Martel, An, Pasmans, Frank, Van Waeyenberghe, Lieven   +7 more
core   +2 more sources

Mucor and Aspergillus Maxillary Bone and Sinuses coinfection in a woman with Systemic Lupus Erythematosus: A Case Report

Novelty in Biomedicine
Background: Mucorales and Aspergillus have invasive fungal infections with high mortality, mainly in immunocompromised and diabetic patients. The diagnosis is microbiological and pathological, with a strong clinical suspicion.
Hassan Mir Mohammad Sadeghi, Azin Kheradmand, Simin Dokht Shoaei   +2 more
doaj   +1 more source

Steric‐Adaptive Biocatalysis: Imine Reductase‐Mediated Dynamic Kinetic Resolution for Atroposelective Synthesis of Hindered Biaryl Amines

Advanced Science, EarlyView.
An unusual IRED platform is reported, enabling efficient DKR via reductive amination without any evolutionary engineering. The system accommodates extremely sterically demanding substrates, including naphthyl and quinoline derivatives, delivering naphthyl‐aryl and quinoline‐aryl amine atropisomers with excellent efficiency and stereocontrol (over 80 ...
Zhichao Ni, Jingyuan Zhuang, Yadong Gao, Guangsheng Gao, Zhenling Liu, Ping Su, Gui‐Juan Cheng, Li‐Cheng Yang   +7 more
wiley   +1 more source

Balancing Cell Growth and Product Synthesis for Efficient Microbial Cell Factories

Advanced Science, EarlyView.
This review presents state‐of‐the‐art metabolic engineering strategies to balance microbial cell growth and product synthesis in biorefineries. It surveys pathway engineering, dynamic genetic circuits, orthogonal control systems, synthetic microbial consortia, and fermentation optimization, alongside integrative modeling approaches.
Linxia Liu, Dongqin Ding, Huiying Wang, Xinyi Ren, Sang Yup Lee, Dawei Zhang   +5 more
wiley   +1 more source

Validation and clinical application of molecular methods for the identification of molds in tissue [PDF]

, 2006
Background. Invasive fungal infections due to less-common molds are an increasing problem, and accurate diagnosis is difficult.Methods. We used our previously established molecular method, which allows species identification of molds in histological ...
Kibbler, CC, McHugh, TD, McLaughlin, J, Paterson, PJ, Potter, M, Prentice, HG, Seaton, S   +6 more
core   +1 more source

One‐Pot Encapsulation of Enzymes in a Calcium Carboxylate Metal‐Organic Framework for Improved Buffer Stability

Advanced Science, EarlyView.
A biocompatible, room‐temperature synthesis of Ca2⁺–4,5‐imidazoledicarboxylate MOFs enables in situ encapsulation of diverse enzymes with enhanced stability in phosphate buffer. A machine learning workflow integrating Latin hypercube sampling efficiently navigates the synthesis space, optimizing encapsulation efficiency, retained enzymatic activity ...
Ying Shu, Weibin Liang, Jun Huang
wiley   +1 more source

Monitoring bioaerosol and odour emissions from composting facilities - WR1121 [PDF]

, 2013
Government policy requires that valuable resources should be recovered and recycled from biodegradable waste. A successful and growing organics recycling industry delivers this policy with composting being one of the principal technologies deployed to ...
Al-Ashaab, Reyna, Butterfield, David, Coughlin, Toni, Drew, Gillian, Gladding, Toni, Hansell, Anna, Lamarre, Baptiste, Longhurst, Phil, Nelson, Alan, Simpson, Annika, Tyrrel, Sean, Williams, Melanie   +11 more
core  

3D Printing of α‐Amylase‐Illuminated Fluorescent Devices for Dynamic Information Storage and Encryption

Aggregate, EarlyView.
A α‐amylase‐stimulated responsive fluorescent hydrogel system was used to store information with arbitrary architectures through combining 3D printing technology. ABSTRACT Traditional fluorescent materials for information encryption have drawbacks such as low resolution and cumbersome process of information loading.
Jiongcheng Lu, Jiawei Lin, Ran Chen, Qian Sun, Zhenxing Wang, Wen Huang, Lili Cai, Xuetao Shi, Meng Zhang, Kaojin Wang, Lin Wang, Yong‐Guang Jia, Xiaoxia Zhu   +12 more
wiley   +1 more source