Results 91 to 100 of about 186,086 (280)

Molecular IgE Sensitization Profiling With Micro‐Arrayed Allergen Molecules in Adult Patients With Asthma From the LEAD Cohort: A Precision Medicine Approach

Allergy, EarlyView.
In the LEAD cohort, micro‐arrayed asthma allergens identified IgE‐sensitized adult asthma patients. Compared to non‐IgE‐sensitized patients, they had better lung function, took less ICS and had lower eosinophils. IgE‐sensitized patients were sensitized to a handful of respiratory allergen sources and may benefit from allergen‐specific forms of ...
Huey‐Jy Huang, Robab Breyer‐Kohansal, Katarzyna Niespodziana, Charmaine J. M. Lim, Marie‐Kathrin Breyer, Rudolf Valenta, Sylvia Hartl, the Allergochip Working Group, Maria‐Roxana Buzan, Kuan‐Wei Chen, Monica Daniela Cotarcă, Alexandra Dubovets, Pia Gattinger, Alexander Karaulov, Evgenii Kozlov, Carmen Panaitescu, Daria Trifonova, Mikhail Tulaev, Susanne Vrtala, Milena Weber, Lauriana‐Eunice Zbîrcea   +20 more
wiley   +1 more source

Rezafungin (CD101) demonstrates potent in vitro activity against Aspergillus, including azole-resistant Aspergillus fumigatus isolates and cryptic species

Journal of Antimicrobial Chemotherapy, 2018
Background Rezafungin is an investigational echinocandin under development for the treatment and prevention of invasive fungal infections, with a long half-life in humans (∼130 h) and potent in vitro activity against Aspergillus spp. Our objective was to
N. Wiederhold, J. B. Locke, P. Daruwala, K. Bartizal   +3 more
semanticscholar   +1 more source

Investigation of four diagnostic methods to identify infectious ulcerative keratitis in horses in Colorado, USA

Equine Veterinary Education, EarlyView.
Summary Background Ulcerative keratitis in equine patients can result in keratomalacia and perforation. Prompt and accurate diagnostics are necessary for appropriate therapy and a favourable outcome. Objective To determine the diagnostic utility (specificity and speed) of four diagnostic methods for infectious ulcerative keratitis in the horse.
K. E. V. Jones, M. R. Lappin, J. B. Daniels, J. Sharp, J. Hawley, M. d. L. Henriksen   +5 more
wiley   +1 more source

SENSIBILIZAÇÃO FÚNGICA PARA ASPERGILLUS FUMIGATUS E FUSARIUM SP. EM PACIENTES ASMÁTICOS DE SÃO LUÍS - MA

Cadernos de Pesquisa, 2014
A sensibilização a fungos tem associação documentada com as doenças alérgicas respirató-rias e podem desencadear crise de asma em pacientes predispostos.
José Alvaro Amaral Júnior, Maria do Rosário da Silva Ramos Costa, André Luiz de Araújo Mendes, Denicy Alves Pereira Ferreira   +3 more
doaj   +1 more source

Emerging threat of triazole-resistant Aspergillus fumigatus

Journal of Antimicrobial Chemotherapy, 2018
Invasive aspergillosis is a leading cause of morbidity and mortality among immunocompromised populations and is predicted to cause more than 200 000 life-threatening infections each year. Aspergillus fumigatus is the most prevalent pathogen isolated from
J. Rybak, J. Fortwendel, P. Rogers
semanticscholar   +1 more source

Considerations and challenges of septic arthritis and osteomyelitis

Equine Veterinary Education, EarlyView.
Summary Septic arthritis remains a common orthopaedic condition in both human and veterinary medicine which can cause serious morbidity and pose considerable challenges for clinical management. The majority of the published clinical research in humans and veterinary species has been focused on the diagnosis, treatment, prevention and outcome of this ...
J. B. Engiles, H. L. Stewart
wiley   +1 more source

Advances in Aspergillus fumigatus Pathobiology

, 2016
Aspergillus fumigatus is a human fungal pathogen that causes invasive aspergillosis (IA), a major infectious cause of death in the expanding population of immunocompromised individuals such as cancer patients and transplant recipients. The mortality of IA remains high (30-70%) and emerging resistance to triazoles, the first-line antifungal drug class ...
William J. Steinbach, Praveen R. Juvvadi, Frédéric Lamoth   +2 more
openaire   +3 more sources

DNA Aptamers Targeting BcSOD1: A Novel Strategy for Controlling Botrytis cinerea in Sustainable Agriculture

Plant Biotechnology Journal, EarlyView.
ABSTRACT Botrytis cinerea, the necrotrophic fungus responsible for grey mould disease, is a major threat to global crop production. Control strategies mainly rely on chemical fungicides, but resistance development limits their long‐term effectiveness. This study introduces, for the first time in crop protection, the use of DNA aptamers as a novel and ...
Alba López‐Laguna, Álvaro Polonio, Lucía Jiménez‐Castro, Yandira Morales, Alejandra Vielba‐Fernández, M. Elena Martín, Víctor M. González, Antonio de Vicente, Alejandro Pérez‐García, Dolores Fernández‐Ortuño   +9 more
wiley   +1 more source

Identification and Isolation of fungus from food and determination of its antibacterial activity

RADS Journal of Biological Research & Applied Science, 2017
The issue of drug resistant pathogens is the most well-known issue now days. Irresistible and parasitic infections are still the second driving reason for death. This is the major cause to examine their antibacterial activity. The antimicrobial compounds
Ada Jafri, Sayyada Ghufrana Nadeem
doaj  

Central nervous system Aspergillus fumigatus infection with subarachnoid haemorrhage secondary to hemophagocytic lymphohistiocytosis: a rare case report

BMC Neurology
Background Secondary central nervous system (CNS) Aspergillus fumigatus infection leading to subarachnoid hemorrhage following the onset of hemophagocytic lymphohistiocytosis (HLH) represents an extremely rare case.
Siting Wu, Ning Zhao, Yunxing Liang, Weinan Zhang, Fang Cui, Jiacai Lin   +5 more
doaj   +1 more source