Results 121 to 130 of about 186,086 (280)

A Novel Zn2-Cys6 Transcription Factor AtrR Plays a Key Role in an Azole Resistance Mechanism of Aspergillus fumigatus by Co-regulating cyp51A and cdr1B Expressions

open access: yesPLoS Pathogens, 2017
Successful treatment of aspergillosis caused by Aspergillus fumigatus is threatened by an increasing incidence of drug resistance. This situation is further complicated by the finding that strains resistant to azoles, the major antifungal drugs for ...
Daisuke Hagiwara   +13 more
semanticscholar   +1 more source

Chronic Pulmonary Aspergillosis Secondary Infection: A Case Report of Achromobacter spp. Lung Infection

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Both pulmonary tuberculosis (PTB) and coronavirus disease‐2019 (COVID‐19) are risk factors for chronic pulmonary aspergillosis (CPA) and other pulmonary infectious diseases because of residual lung damage. We report a case of Achromobacter spp. infection following CPA in an immunocompetent woman with a history of PTB and COVID‐19.
Marius Paulin Ngouanom Kuate   +2 more
wiley   +1 more source

Improving Diagnostic Accuracy in Respiratory Allergy: Monocentric Reevaluation of the GA2LEN Panel in Germany

open access: yesClinical and Translational Allergy, Volume 15, Issue 10, October 2025.
ABSTRACT Background European guidelines recommend using a standardized baseline series of skin prick test (SPT) allergens for the diagnosis of airway allergies. In addition, local adaptation and/or extension of test panels according to regional exposure and sensitization patterns are increasingly being discussed.
Caroline Beutner   +5 more
wiley   +1 more source

A Simple and Universal System for Gene Manipulation in Aspergillus fumigatus: In Vitro-Assembled Cas9-Guide RNA Ribonucleoproteins Coupled with Microhomology Repair Templates

open access: yesMsphere, 2017
Tackling the multifactorial nature of virulence and antifungal drug resistance in A. fumigatus requires the mechanistic interrogation of a multitude of genes, sometimes across multiple genetic backgrounds. Classical fungal gene replacement systems can be
Q. Al Abdallah, Wenbo Ge, J. Fortwendel
semanticscholar   +1 more source

Late‐Onset Invasive Aspergillosis With Pituitary Involvement and Dysfunction Following CD19 Chimeric Antigen Receptor T‐Cell Therapy

open access: yeseJHaem, Volume 6, Issue 5, October 2025.
ABSTRACT Introduction Invasive fungal infection (IFI) after chimeric antigen receptor (CAR) T‐cell therapy is less common than bacterial and viral infections, but can be fatal once it develops. As most cases occur within 30 days after CAR T‐cell infusion, late‐onset IFI—particularly mould infection—appears to be under‐recognised.
Daisuke Ikeda   +16 more
wiley   +1 more source

Drug susceptibility of Aspergillus flavus and A.fumigatus to Itraconazole and Amphotericin B

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2013
Background and Objective: Aspergillosis is the most current causative agent of exogenous fungal nosocomial infection. This study was done to evaluate the drug susceptibility of Aspergillus flavus and A.fumigatus to itraconazole and amphotericin B ...
Kazemi A   +3 more
doaj  

Aspergillus fumigatus-Related Species in Clinical Practice

open access: yesFrontiers in Microbiology, 2016
Aspergillus fumigatus is the main etiologic agent of invasive aspergillosis (IA). Other Aspergillus species belonging to the section Fumigati (A. fumigatus complex) may occasionally be the cause of IA.
Frederic eLamoth
doaj   +1 more source

Statins as Antifungal Agents: A Review on Drug Repurposing and Nanotechnology‐Driven Delivery Strategies

open access: yesFundamental &Clinical Pharmacology, Volume 39, Issue 5, October 2025.
ABSTRACT This review highlights the integration of drug repurposing and nanotechnology‐driven delivery strategies as innovative approaches to enhance the antifungal activity of statins against mucosal candidiasis, providing a framework for future translational research and clinical application.
Dominique Mesquita e Silva   +8 more
wiley   +1 more source

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