Results 141 to 150 of about 225,540 (315)

A Novel Zn2-Cys6 Transcription Factor AtrR Plays a Key Role in an Azole Resistance Mechanism of Aspergillus fumigatus by Co-regulating cyp51A and cdr1B Expressions

PLoS Pathogens, 2017
Successful treatment of aspergillosis caused by Aspergillus fumigatus is threatened by an increasing incidence of drug resistance. This situation is further complicated by the finding that strains resistant to azoles, the major antifungal drugs for ...
Daisuke Hagiwara, Miura Daisuke, Kiminori, Shimizu, S. Paul, Ayumi Ohba, T. Gonoi, A. Watanabe, K. Kamei, T. Shintani, W. Scott Moye-Rowley, S. Kawamoto, K. Gomi, R. Cramer   +13 more
semanticscholar   +1 more source

Shaping Plant Growth Beneath the Soil: A Theoretical Exploration of Fungal Endophyte's Role as Plant Growth‐Promoting Agents

MicrobiologyOpen, Volume 14, Issue 4, August 2025.
A schematic representation depicting various mechanisms of plant growth promotion by fungal endophytes present in different parts of the plant. Fungal endophytes are present in various parts of the plant, including leaves, stems, and most abundantly in roots.
Riyaz Ahmad Rather
wiley   +1 more source

Frequency and molecular epidemiology of Aspergillus isolated from patients with suspicion of respiratory fungal infection [PDF]

, 2019
Objective: The aim of this study was to determine the frequency of Aspergillus detected in respiratory samples from a cohort of patients with suspicion of fungal infection of the respiratory tract as well as to determine the susceptibility to azoles of ...
Oliveira, M., Sabino, R., Simões, H., Verissimo, C.   +3 more
core  

A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

mBio, 2017
This study investigated the dynamics of Aspergillus fumigatus azole-resistant phenotypes in two compost heaps with contrasting azole exposures: azole free and azole exposed.
Jianhua Zhang, E. Snelders, B. Zwaan, Sijmen E. Schoustra, J. Meis, K. van Dijk, F. Hagen, M. T. van der Beek, G. Kampinga, J. Zoll, W. Melchers, P. Verweij, A. Debets   +12 more
semanticscholar   +1 more source

Linker‐mediated domain separation enhances cold adaptation in cellulases

Protein Science, Volume 34, Issue 8, August 2025.
Abstract Cold‐adapted cellulases have the potential to reduce energy demands in industrial processes by enabling efficient cellulose saccharification at lower temperatures. However, the structural basis of cold adaptation in bidomain cellulases remains poorly understood. Our prior studies on bidomain amylases proposed a “linker spacer effect”—a greater
Robbie Ge, Ning Ding, Yaoyukun Jiang, Zhongyue J. Yang   +3 more
wiley   +1 more source

Prevalence of cutaneous hypersensitivity to Aspergillus fumigatus in patients with asthma in the central part of Karnataka and its impact on asthma severity

Journal of Medical and Scientific Research
Introduction: Severe asthma is particularly linked to atopic conditions, especially to mold allergens like Aspergillus fumigatus. Allergic bronchopulmonary aspergillosis is an immunological lung disorder, with initial phase of hypersensitivity to ...
Bondade K, Ajit E, Raikar PS, Srinivas K, Banur A, Angadi S   +5 more
doaj   +1 more source

Species-Specific Differences in the Susceptibility of Fungi to the Antifungal Protein AFP Depend on C-3 Saturation of Glycosylceramides [PDF]

, 2019
AFP is an antimicrobial peptide (AMP) produced by the filamentous fungus Aspergillus giganteus and is a very potent inhibitor of fungal growth that does not affect the viability of bacteria, plant, or mammalian cells.
Baumann, Birgit, Hagen, Silke, Jung, Sascha, Meyer, Vera, Paege, Norman, Rodrigues, Ana, Thiess, Melanie, Warnecke, Dirk, Zäuner, Simone   +8 more
core   +1 more source

Aspergillus fumigatus and aspergillosis: From basics to clinics

Studies in Mycology, 2021
A. Arastehfar, A. Carvalho, J. Houbraken, L. Lombardi, R. Garcia-Rubio, J. Jenks, O. Rivero-Menendez, R. Aljohani, I. Jacobsen, J. Berman, N. Osherov, M. Hedayati, M. Ilkit, D. Armstrong-James, T. Gabaldón, J. Meletiadis, M. Kostrzewa, W. Pan, C. Lass‐Flörl, D. Perlin, M. Hoenigl   +20 more
semanticscholar   +1 more source

A Simple and Universal System for Gene Manipulation in Aspergillus fumigatus: In Vitro-Assembled Cas9-Guide RNA Ribonucleoproteins Coupled with Microhomology Repair Templates

Msphere, 2017
Tackling the multifactorial nature of virulence and antifungal drug resistance in A. fumigatus requires the mechanistic interrogation of a multitude of genes, sometimes across multiple genetic backgrounds. Classical fungal gene replacement systems can be
Q. Al Abdallah, Wenbo Ge, J. Fortwendel
semanticscholar   +1 more source

Modeling, virtual screening, and enzymatic docking of trehalose 6‐phosphate phosphatase and evaluation of the insecticidal effect of phthalimide, N‐(p‐tolylsulfonyl) on Aedes aegypti (Diptera: Culicidae)

Pest Management Science, Volume 81, Issue 8, Page 4777-4787, August 2025.
Schematic diagram of the experimental procedures used to perform the bioinformatic steps and insecticidal assays using trehalose 6‐phosphate phosphatase of Aedes aegypti and the molecule phthalimide, N‐(p‐tolylsulfonyl). Abstract BACKGROUND Aedes aegypti Linnaeus is a medically important vector because of its role in transmitting several arboviruses ...
Raquel Jemima Viana Lima, Fernando Berton Zanchi, Railton Marques de Souza Guimarães, Alexandre de Almeida e Silva   +3 more
wiley   +1 more source