Results 161 to 170 of about 38,469 (206)

Resistance of Aspergillus fumigatus to Itraconazole

Scandinavian Journal of Infectious Diseases, 1998
ment with the drug. The author concluded that the A. fumigatus strains acquired resistance to itraconazole during or following treatment. The author, however, failed to determine whether or not the isolates cultured from the sputa were genotypically identical. Although invasive infections by Aspergillus species are generally caused by a single genotype
Verweij, P.E., Voss, A., Meis, J.F.G.M.
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Serological studies on Aspergillus fumigatus

Mycopathologia et Mycologia Applicata, 1961
1) Extract was obtained by repeated cryolysis of acetone-dried mycelia ofAsp. fumigatus killed by formalin. High titer immune serum could be easily obtained by immunizing rabbits with this extract.
M, FUKUI, J, YASUDA
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Metabolism of progesterone by Aspergillus fumigatus

Journal of Steroid Biochemistry, 1982
Abstract Metabolism of progesterone by a typical strain of Aspergillus fumigatus was studied. The four metabolites isolated were characterized as 5α-pregnane-3s-ol-20-one, 15s-hydroxy-1,4-pregnadiene-3,20-dione, 7s,15s-dihydroxy-4-pregnene-3,20-dione and 11α,15s-dihydroxy-4-pregnene-3,20-dione by the application of various spectrometric techniques.
A, Mukherjee, S, Banerjee, S B, Mahato
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Biodegradation of anthracene by Aspergillus fumigatus

Journal of Hazardous Materials, 2011
An anthracene-degrading strain, identified as Aspergillus fumigatus, showed a favorable ability in degradation of anthracene. The degradation efficiency could be maintained at about 60% after 5d with initial pH of the medium kept between 5 and 7.5, and the optimal temperature of 30 °C.
Jin-Shao, Ye, Hua, Yin, Jing, Qiang, Hui, Peng, Hua-Ming, Qin, Na, Zhang, Bao-Yan, He   +6 more
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Developmental regulators in Aspergillus fumigatus

Journal of Microbiology, 2016
The filamentous fungus Aspergillus fumigatus is the most prevalent airborne fungal pathogen causing severe and usually fatal invasive aspergillosis in immunocompromised patients. This fungus produces a large number of small hydrophobic asexual spores called conidia as the primary means of reproduction, cell survival, propagation, and infectivity.
Hee-Soo, Park, Jae-Hyuk, Yu
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Itraconazole resistance in Aspergillus fumigatus

Antimicrobial Agents and Chemotherapy, 1997
Invasive aspergillosis is an increasingly frequent opportunistic infection in immunocompromised patients. Only two agents, amphotericin B and itraconazole, are licensed for therapy. Itraconazole acts through inhibition of a P-450 enzyme undertaking sterol 14alpha demethylation.
Denning, David W.; id_orcid 0000-0001-5626-2251, Venkateswarlu, K., Oakley, Karen L., Anderson, M. J., Manning, N. J., Stevens, David A., Warnock, David W., Kelly, Steven L.   +7 more
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Production of melanin by Aspergillus fumigatus

Journal of Medical Microbiology, 2004
Melanins, or melanin-like compounds, may play a role in the pathogenesis of a number of human fungal infections. This study investigated the production of melanin by the important opportunistic pathogen Aspergillus fumigatus. Conidia from A. fumigatus were harvested and treated with proteolytic enzymes, denaturant and hot, concentrated acid; this ...
Youngchim, S, Morris-Jones, R, Hay, R J, Hamilton, A J   +3 more
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Metabolomics ofAspergillus fumigatus

Medical Mycology, 2009
Aspergillus fumigatus is the most important species in Aspergillus causing infective lung diseases. This species has been reported to produce a large number of extrolites, including secondary metabolites, acids, and proteins such as hydrophobins and extracellular enzymes.
Jens C, Frisvad, Christian, Rank, Kristian F, Nielsen, Thomas O, Larsen   +3 more
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Sequencing the Aspergillus fumigatus genome

The Lancet Infectious Diseases, 2002
Aspergillus fumigatus is the most common mould pathogen of human beings and unusually causes both invasive disease in immunocompromised patients and allergic disease in patients with atopic immune systems. 4% of patients dying in modern European teaching hospitals have invasive aspergillosis and it is the leading infectious cause of death in leukaemia ...
Denning, David W.; id_orcid 0000-0001-5626-2251, Anderson, Michael J., Turner, Geoffrey, Latgé, Jean Paul, Bennett, Joan W.   +4 more
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Insertional mutagenesis of Aspergillus fumigatus

Molecular and General Genetics MGG, 1998
We have investigated transformation with heterologous DNA as a method for insertional mutagenesis of Aspergillus fumigatus. Two methods, polyethylene glycol-mediated transformation of protoplasts and electroporation of germinating spores, were used to establish conditions leading to single-copy integration of transforming DNA at different genomic sites.
J S, Brown, A, Aufauvre-Brown, D W, Holden   +2 more
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