Results 21 to 30 of about 186,086 (280)

Role of Hydrophobins in Aspergillus fumigatus [PDF]

Journal of Fungi, 2017
Resistance of Aspergillus fumigatus conidia to desiccation and their capacity to reach the alveoli are partly due to the presence of a hydrophobic layer composed of a protein from the hydrophobin family, called RodA, which covers the conidial surface. In A. fumigatus there are seven hydrophobins (RodA–RodG) belonging to class I and III.
John G. Gibbons, Rémi Beau, Jean-Yves Coppée, Emmanuel Stephen-Victor, Emmanuel Stephen-Victor, J. Iñaki Guijarro, Jagadeesh Bayry, Jagadeesh Bayry, Vincent Dupres, Isabel Valsecchi, Frank Lafont, Jean-Paul Latgé, Anne Beauvais   +12 more
openaire   +4 more sources

The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus

Nature Communications, 2020
The frequency of antifungal resistance, particularly to the azole class of ergosterol biosynthetic inhibitors, is a growing global health problem. Survival rates for those infected with resistant isolates are exceptionally low. Beyond modification of the
Takanori Furukawa, N. van Rhijn, M. Fraczek, F. Gsaller, Emma Davies, P. Carr, S. Gago, Rachael Fortune-Grant, Sayema Rahman, J. Gilsenan, E. Houlder, Caitlin H. Kowalski, Shriya Raj, S. Paul, P. Cook, J. Parker, S. Kelly, R. Cramer, J. Latgé, S. Moye-Rowley, E. Bignell, P. Bowyer, M. Bromley   +22 more
semanticscholar   +1 more source

Catalases of Aspergillus fumigatus [PDF]

Infection and Immunity, 2003
ABSTRACT Upon infection of a host, the pathogenic fungus Aspergillus fumigatus is attacked by the reactive oxygen species produced by phagocytic cells. Detoxification of hydrogen peroxide by catalases was proposed as a way to overcome this host response. A.
Richard D. Diamond, Sophie Paris, Deborah R. Wysong, Bruno Philippe, Kazutoshi Shibuya, Jean-Paul Latgé, J P Debeaupuis   +6 more
openaire   +3 more sources

PREDICTION OF ANTIFUNGAL ACTIVITY OF 1,2,4-TRIAZOLE DERIVATIVES USING QSAR MODELS

Siberian Journal of Life Sciences and Agriculture, 2023
Purpose. Development of QSAR models and investigation of their effectiveness for predicting the antifungal activity of 1,2,4-triazole derivatives against Aspergillus flavus, Aspergillus fumigatus and Trichophyton mentagrophytes. Materials and methods.
Alexander L. Osipov
doaj   +1 more source

On the lineage of Aspergillus fumigatus isolates in common laboratory use.

Medical Mycology, 2020
The origin of isolates routinely used by the community of Aspergillus fumigatus researchers is periodically a matter of intense discussion at our centre, as the construction of recombinant isolates have sometimes followed convoluted routes, the ...
M. Bertuzzi, N. van Rhijn, S. Krappmann, P. Bowyer, M. Bromley, E. Bignell   +5 more
semanticscholar   +1 more source

Mechanisms of Triazole Resistance in Aspergillus fumigatus.

Environmental Microbiology, 2020
The ubiquitous fungal pathogen Aspergillus fumigatus is the primary cause of opportunistic mold infections in humans. Aspergilli disseminate via asexual conidia passively traveling through air currents to germinate within a broad range of environs ...
Ashley V. Nywening, J. Rybak, P. Rogers, J. Fortwendel   +3 more
semanticscholar   +1 more source

Concordance between Aspergillus-specific precipitating antibody and IgG in allergic bronchopulmonary aspergillosis

Allergology International, 2018
s: Background: Several serological tests for specific precipitin or IgG are available to demonstrate type III hypersensitivity reactions to Aspergillus species and are essential for infectious fungal disease diagnosis.
Kazuki Harada, Tsuyoshi Oguma, Akemi Saito, Yuma Fukutomi, Jun Tanaka, Katsuyoshi Tomomatsu, Masami Taniguchi, Koichiro Asano   +7 more
doaj   +1 more source

A Whole Genome Sequencing-Based Approach to Track down Genomic Variants in Itraconazole-Resistant Species of Aspergillus from Iran

Journal of Fungi, 2022
The antifungal resistance in non-fumigatus Aspergillus spp., as well as Aspergillus fumigatus, poses a major therapeutic challenge which affects the entire healthcare community.
Sanaz Nargesi, Reza Valadan, Mahdi Abastabar, Saeed Kaboli, Jose Thekkiniath, Mohammad Taghi Hedayati   +5 more
doaj   +1 more source

Mac‐1 triggers neutrophil DNA extracellular trap formation to Aspergillus fumigatus independently of PAD4 histone citrullination

Journal of Leukocyte Biology, 2020
Aspergillus fumigatus (A. fumigatus) is an environmental fungus and a human pathogen. Neutrophils are critical effector cells during the fungal infections, and neutropenia is a risk factor for the development of pulmonary aspergillosis.
J. C. Silva, Najara C. Rodrigues, Glaucia A. Thompson-Souza, Valdirene S. Muniz, J. S. Neves, R. Figueiredo   +5 more
semanticscholar   +1 more source

FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection.

PLoS Pathogens, 2016
The immune mechanisms that recognize inhaled Aspergillus fumigatus conidia to promote their elimination from the lungs are incompletely understood.
Sheena C Kerr, Gregory J Fischer, Meenal Sinha, Orla McCabe, Jonathan M Palmer, Tsokyi Choera, Fang Yun Lim, Michaela Wimmerova, Stephen D Carrington, Shaopeng Yuan, Clifford A Lowell, Stefan Oscarson, Nancy P Keller, John V Fahy   +13 more
doaj   +1 more source