Results 21 to 30 of about 232,874 (323)

Extensive Non-Coding Sequence Divergence Between the Major Human Pathogen Aspergillus fumigatus and its Relatives

Frontiers in Fungal Biology, 2022
Invasive aspergillosis is a deadly fungal disease; more than 400,000 patients are infected worldwide each year and the mortality rate can be as high as 50-95%.
Alec Brown, Alec Brown, Matthew E. Mead, Matthew E. Mead, Jacob L. Steenwyk, Jacob L. Steenwyk, Gustavo H. Goldman, Antonis Rokas, Antonis Rokas   +8 more
doaj   +1 more source

Development and clinical implications of a novel CRISPR-based diagnostic test for pulmonary Aspergillus fumigatus infection

Journal of Microbiology, Immunology and Infection, 2022
Background: Rapid and reliable diagnostic methods for Aspergillus fumigatus infection are urgently needed. Clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein 13a (Cas13a) has high sensitivity and specificity in the ...
Zhengtu Li, Mingdie Wang, Teng Xu, Yangqing Zhan, Fengyi Chen, Ye Lin, Shaoqiang Li, Jing Cheng, Feng Ye   +8 more
doaj   +1 more source

Glycosylinositolphosphoceramides in Aspergillus Fumigatus [PDF]

Glycobiology, 2007
Fungal glycosylinositolphosphoceramides (GIPCs) are involved in cell growth and fungal-host interactions. In this study, six GIPCs from the mycelium of the human pathogen Aspergillus fumigatus were purified and characterized using Q-TOF mass spectrometry and 1H, 13C, and 31P NMR.
Simenel, Catherine, Coddeville, Bernadette, Delepierre, Muriel, Latgé, Jean-Paul, Fontaine, Thierry   +4 more
openaire   +3 more sources

PREDICTION OF ANTIFUNGAL ACTIVITY OF 1,2,4-TRIAZOLE DERIVATIVES USING QSAR MODELS

Siberian Journal of Life Sciences and Agriculture, 2023
Purpose. Development of QSAR models and investigation of their effectiveness for predicting the antifungal activity of 1,2,4-triazole derivatives against Aspergillus flavus, Aspergillus fumigatus and Trichophyton mentagrophytes. Materials and methods.
Alexander L. Osipov
doaj   +1 more source

The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus

Nature Communications, 2020
The frequency of antifungal resistance, particularly to the azole class of ergosterol biosynthetic inhibitors, is a growing global health problem. Survival rates for those infected with resistant isolates are exceptionally low. Beyond modification of the
Takanori Furukawa, N. van Rhijn, M. Fraczek, F. Gsaller, Emma Davies, P. Carr, S. Gago, Rachael Fortune-Grant, Sayema Rahman, J. Gilsenan, E. Houlder, Caitlin H. Kowalski, Shriya Raj, S. Paul, P. Cook, J. Parker, S. Kelly, R. Cramer, J. Latgé, S. Moye-Rowley, E. Bignell, P. Bowyer, M. Bromley   +22 more
semanticscholar   +1 more source

A Whole Genome Sequencing-Based Approach to Track down Genomic Variants in Itraconazole-Resistant Species of Aspergillus from Iran

Journal of Fungi, 2022
The antifungal resistance in non-fumigatus Aspergillus spp., as well as Aspergillus fumigatus, poses a major therapeutic challenge which affects the entire healthcare community.
Sanaz Nargesi, Reza Valadan, Mahdi Abastabar, Saeed Kaboli, Jose Thekkiniath, Mohammad Taghi Hedayati   +5 more
doaj   +1 more source

Aspergillus fumigatus enhances elastase production in pseudomonas aeruginosaco-cultures [PDF]

, 2015
In the cystic fibrosis (CF) lung the presence of bacteria and fungi in the airways promotes an inflammatory response causing progressive lung damage, ultimately leading to high rates of morbidity and mortality.
Kerr, Stephen, Lappin, David F., Mackay, William G., Rajendran, Ranjith, Ramage, Gordon, Smith, Karen, Williams, Craig   +6 more
core   +1 more source

Concordance between Aspergillus-specific precipitating antibody and IgG in allergic bronchopulmonary aspergillosis

Allergology International, 2018
s: Background: Several serological tests for specific precipitin or IgG are available to demonstrate type III hypersensitivity reactions to Aspergillus species and are essential for infectious fungal disease diagnosis.
Kazuki Harada, Tsuyoshi Oguma, Akemi Saito, Yuma Fukutomi, Jun Tanaka, Katsuyoshi Tomomatsu, Masami Taniguchi, Koichiro Asano   +7 more
doaj   +1 more source

Microsatellite typing of avian clinical and environmental isolates of Aspergillus fumigatus [PDF]

, 2011
Aspergillosis is one of the most common causes of death in captive birds. Aspergillosis in birds is mainly caused by Aspergillus fumigatus, a ubiquitous and opportunistic saprophyte.
Beernaert, Lies, Dorrestein, Gerry M, Haesebrouck, Freddy, Klaassen, Corné HW, Martel, An, Pasmans, Frank, Van Waeyenberghe, Lieven, Vercammen, Francis, Verstappen, Frank   +8 more
core   +3 more sources

On the lineage of Aspergillus fumigatus isolates in common laboratory use.

Medical Mycology, 2020
The origin of isolates routinely used by the community of Aspergillus fumigatus researchers is periodically a matter of intense discussion at our centre, as the construction of recombinant isolates have sometimes followed convoluted routes, the ...
M. Bertuzzi, N. van Rhijn, S. Krappmann, P. Bowyer, M. Bromley, E. Bignell   +5 more
semanticscholar   +1 more source