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International Journal of Cancer, 2019 Aspirin, commonly used for prevention of cardiovascular and cerebrovascular diseases, has been found to possess protective effects against cancer development in the Western populations. Such effects among Asian populations remain uncertain. The objective
Kelvin Tsoi +2 more
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The prevalence and associated factors of aspirin resistance among prophylactic aspirin users [PDF]
Romanian Journal of Neurology, 2021 Background. Aspirin is an antiplatelet used for the secondary prevention after vascular events. It is also suggested for the primary prevention of vascular events in high risk people, however, despite using standard prophylactic doses, aspirin resistance
Samaneh Ghorbani-Shirkouhi +5 more
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Journal of Cardiovascular Development and Disease, 2023 Aspirin inhibits platelet function by irreversibly inhibiting the synthesis of thromboxane A2 (TxA2). Aspirin, at low doses, is widely used for cardiovascular prevention. Gastrointestinal discomfort, mucosal erosions/ulcerations and bleeding are frequent
Bianca Clerici, Marco Cattaneo
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Journal of the American Medical Association (JAMA), 2022 Importance Cardiovascular disease (CVD) is the leading cause of mortality in the US, accounting for more than 1 in 4 deaths. Each year, an estimated 605 000 people in the US have a first myocardial infarction and an estimated 610 000 experience a first ...
K. Davidson +17 more
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Circulation, 2000 Acetylsalicylic acid, or aspirin, is a synthetic compound with antipyretic, analgesic, anti-inflammatory, and antiplatelet properties. Since its introduction into the commercial market in June 1899, it has become one of the most versatile pharmaceutical agents known, with demonstrated efficacy in a myriad of clinical settings.
Eric H. Awtry, Joseph Loscalzo
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Frontiers in Oncology, 2022 Gonadotropin-releasing hormone (GnRH) therapy has been known to increase risks of major adverse cardiovascular and cerebrovascular events (MACCEs). Herein, we aim to estimate whether regular use of aspirin attenuates risks of MACCEs in prostate cancer ...
Wei-Ting Chang +15 more
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Research and Practice in Thrombosis and Haemostasis, 2021 Background Aspirin is important for preventing thrombotic events but also increases bleeding complications. Minimizing bleeding while preventing thrombotic events remains challenging in patients undergoing coronary artery bypass grafting (CABG ...
Laura M. Willemsen +10 more
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The dissolution of aspirin and aspirin tablets [PDF]
Journal of Pharmacy and Pharmacology, 1967 Abstract An attempt has been made to standardize the “beaker” method of measuring in vitro dissolution rates of tablets against published data for aspirin. An unexpected problem arose when it was found that samples of commercial aspirin have different intrinsic dissolution rates.
Dorothy J. Saville, A. G. Mitchell
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Pharmaceutics, 2023 Acid-reducing agents are commonly used for the prevention of aspirin-induced gastrointestinal complications such as peptic ulcers. As a novel potassium-competitive acid blocker, fexuprazan is expected to prevent aspirin-induced gastrointestinal ...
JungJin Oh +7 more
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