Results 1 to 10 of about 207,435 (308)

The prevalence and associated factors of aspirin resistance among prophylactic aspirin users [PDF]

Romanian Journal of Neurology, 2021
Background. Aspirin is an antiplatelet used for the secondary prevention after vascular events. It is also suggested for the primary prevention of vascular events in high risk people, however, despite using standard prophylactic doses, aspirin resistance
Samaneh Ghorbani-Shirkouhi, Fatemeh Ashouri, Saeideh Aghayari Sheikh Neshin, Alia Saberi, Bahador Hasanzadeh, Parisa Shahshahani   +5 more
doaj   +1 more source

Pharmacological Efficacy and Gastrointestinal Safety of Different Aspirin Formulations for Cardiovascular Prevention: A Narrative Review

Journal of Cardiovascular Development and Disease, 2023
Aspirin inhibits platelet function by irreversibly inhibiting the synthesis of thromboxane A2 (TxA2). Aspirin, at low doses, is widely used for cardiovascular prevention. Gastrointestinal discomfort, mucosal erosions/ulcerations and bleeding are frequent
Bianca Clerici, Marco Cattaneo
doaj   +1 more source

Regular use of aspirin is associated with a lower cardiovascular risk in prostate cancer patients receiving gonadotropin-releasing hormone therapy

Frontiers in Oncology, 2022
Gonadotropin-releasing hormone (GnRH) therapy has been known to increase risks of major adverse cardiovascular and cerebrovascular events (MACCEs). Herein, we aim to estimate whether regular use of aspirin attenuates risks of MACCEs in prostate cancer ...
Wei-Ting Chang, Wei-Ting Chang, Wei-Ting Chang, Chon-Seng Hong, Chon-Seng Hong, Kun-Lin Hsieh, Kun-Lin Hsieh, Yi-Chen Chen, Chung−Han Ho, Chung−Han Ho, Jhih-Yuan Shih, Jhih-Yuan Shih, Wei-Chih Kan, Wei-Chih Kan, Zhih-Cherng Chen, You-Cheng Lin   +15 more
doaj   +1 more source

Blood loss after coronary artery bypass by aspirin responsiveness assessed with preoperative VerifyNow aspirin testing

Research and Practice in Thrombosis and Haemostasis, 2021
Background Aspirin is important for preventing thrombotic events but also increases bleeding complications. Minimizing bleeding while preventing thrombotic events remains challenging in patients undergoing coronary artery bypass grafting (CABG ...
Laura M. Willemsen, Eline A. Vlot, Paul W. A. Janssen, Claire D. Visser, Kai Zheng, Johannes C. Kelder, Peter G. Noordzij, Erik‐Jan van den Dool, Patrick Klein, Christian M. Hackeng, Jurrien M. ten Berg   +10 more
doaj   +1 more source

Pharmacodynamic and Pharmacokinetic Drug Interactions between Fexuprazan, a Novel Potassium-Competitive Inhibitor, and Aspirin, in Healthy Subjects

Pharmaceutics, 2023
Acid-reducing agents are commonly used for the prevention of aspirin-induced gastrointestinal complications such as peptic ulcers. As a novel potassium-competitive acid blocker, fexuprazan is expected to prevent aspirin-induced gastrointestinal ...
JungJin Oh, Eunsol Yang, In-Jin Jang, Hyejung Lee, Hokyun Yoo, Jae-Yong Chung, SeungHwan Lee, Jaeseong Oh   +7 more
doaj   +1 more source

Promoting Aspirin Use for Cardiovascular Disease Prevention Among an Adult Internet-Using Population: A Pilot Study

Frontiers in Public Health, 2021
Cardiovascular disease prevention strategies include aspirin use as a preventive measure. The internet can be used to raise public awareness, promote healthy lifestyles, and improve disease management.
Niki C. Oldenburg, Keith J. Horvath, Jeremy Van't Hof, Jeffrey R. Misialek, Alan T. Hirsch   +4 more
doaj   +1 more source

Mechanistic view into the therapeutic effect, anticancer potential and the adverse effect of aspirin [PDF]

MATEC Web of Conferences
In this research, the working mechanism behind the therapeutic effect of aspirin will be discussed in detail. Aspirin will also be assessed as a promising drug to treat cancerous cells in the future.
Ouyang Juan
doaj   +1 more source

Aspirin decreases hepatocellular carcinoma risk in hepatitis C virus carriers: a nationwide cohort study

BMC Gastroenterology, 2020
Background Aspirin has been found to lower the occurrence rates of some cancers through the inhibition of the cyclooxygenase enzyme. For example, there is a well-known association between aspirin use and the occurrence of hepatocellular carcinoma (HCC ...
Yen-Hsiang Liao, Ren-Jun Hsu, Tzu-Hwei Wang, Chen-Ta Wu, Sheng-Yao Huang, Chung-Y. Hsu, Yuan-Chih Su, Wen-Lin Hsu, Dai-Wei Liu   +8 more
doaj   +1 more source

The targets of aspirin in bladder cancer: bioinformatics analysis

BMC Urology, 2022
Background The anti-carcinogenic properties of aspirin have been observed in some solid tumors. However, the molecular mechanism of therapeutic effects of aspirin on bladder cancer is still indistinct. We introduced a bioinformatics analysis approach, to
Xiao Li, Yanghao Tai, Shuying Liu, Yating Gao, Kaining Zhang, Jierong Yin, Huijuan Zhang, Xia Wang, Xiaofei Li, Dongfeng Zhang, Dong-feng Zhang   +10 more
doaj   +1 more source

Application of low dose aspirin in pre-eclampsia

Frontiers in Medicine, 2023
Aspirin is widely used in the primary and secondary prevention of cardiovascular and cerebrovascular diseases. Low-dose aspirin is also widely used to prevent pre-eclampsia and fetal growth retardation in utero.
Yu Ren, Yong Zhao, Xiangdong Yang, Chaojun Shen, Hua Luo   +4 more
doaj   +1 more source