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Journal of the American Medical Association, 1911 InThe JournalI recently read a communication 1 in regard to idiosyncrasy to aspirin, of which I had an almost parallel case on November 19. On the advice of a friend a young man took a five-grain tablet of aspirin for headache. In about one hour, still suffering, he took another, and then lay down on a cot in his office.
openaire +2 more sources
Aspirin resistance in patients with acute coronary syndrome. Part 1
Кардиоваскулярная терапия и профилактика, 2010 Aim. To evaluate the prevalence of aspirin resistance, its clinical features, potential solutions, and prognostic role in patients with acute coronary syndrome (ACS). Material and methods. The study included 51 patients with ACS and ST segment elevation (
N. S. Frolova +4 more
doaj
Aspirin inhibits colon cancer cell and tumor growth and downregulates specificity protein (Sp) transcription factors. [PDF]
PLoS ONE, 2012 Acetylsalicylic acid (aspirin) is highly effective for treating colon cancer patients postdiagnosis; however, the mechanisms of action of aspirin in colon cancer are not well defined.
Satya Pathi +5 more
doaj +1 more source
Principal Stratification with Time-to-Event Outcomes [PDF]
arXiv, 2023 Post-randomization events, also known as intercurrent events, such as treatment noncompliance and censoring due to a terminal event, are common in clinical trials. Principal stratification is a framework for causal inference in the presence of intercurrent events.
arxiv
Low-dose aspirin for primary and secondary prevention of cardiovascular events in Denmark 1998–2018
Scientific Reports, 2021 Randomised controlled trials have shown a neutral or even unfavourable risk–benefit balance of aspirin for primary prevention of cardiovascular events. Using Danish nationwide registries, we investigated aspirin use and associated risks during the past ...
Mikkel B. Christensen +5 more
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Ascorbic acid enhances the inhibitory effect of aspirin on neuronal cyclooxygenase-2-mediated prostaglandin E2 production [PDF]
Journal of Neuroimmunology 174(1-2): 39-51 (2006), 2007 In the present study, we show that ascorbic acid dose-dependently inhibited interleukin-1beta (IL-1beta)-mediated PGE2 synthesis in the human neuronal cell line, SK-N-SH. Furthermore, in combination with aspirin, ascorbic acid augmented the inhibitory effect of aspirin on PGE2 synthesis. However, ascorbic acid had no synergistic effect along with other
arxiv
Frontiers in PharmacologyObjectiveIn addition to its antiplatelet and anti-inflammatory properties, aspirin inhibits bacterial proliferation directly. The potential benefits of aspirin may enhance the prognosis for sepsis patients.
Chunsheng Huang +3 more
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Detect Adverse Drug Reactions for Drug Aspirin [PDF]
arXiv, 2014 Adverse drug reaction (ADR) is widely concerned for public health issue. In this study we propose an original approach to detect the ADRs using feature matrix and feature selection. The experiments are carried out on the drug Aspirin. Major side effects for the drug are detected and better performance is achieved compared to other computerized methods.
arxiv
Trauma Surgery & Acute Care OpenObjective The perioperative management of patients on antiplatelet drugs is a rising challenge in orthopedic trauma because antiplatelet drugs are frequently encountered and carry an increased risk of hemorrhagic consequences.
Michael Fisher +6 more
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