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From human Megakaryocytes to platelets: Effects of aspirin on high-mobility group Box 1/receptor for advanced glycation end products axis [PDF]
, 2018 Platelets (PLTs) are the major source of high-mobility group box 1 (HMGB1), a protein that is involved in sterile inflammation of blood vessels and thrombosis.
Alessandra Zicari +9 more
core +2 more sources
Aspirin resistance in patients with acute coronary syndrome. Part 2
Кардиоваскулярная терапия и профилактика, 2011 Aim. In patients with acute coronary syndrome (ACS), to investigate the prevalence of aspirin resistance, its clinical features, prognostic effects, and potential correction. Material and methods.
N. S. Frolova +4 more
doaj +1 more source
Frequency of Aspirin Resistance in Ischemic Stroke Patients and Healthy Controls from Colombia
Stroke Research and Treatment, 2021 Objective. To evaluate the aspirin resistance prevalence in patients with previous ischemic cerebrovascular disease undergoing aspirin therapy for secondary prevention. Materials and Methods.
Alejandro Roman-Gonzalez +12 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Aspirin is widely administered to prevent cardiovascular disease (CVD). However, appropriate use of aspirin depends on patient understanding of its risks, benefits, and indications, especially where aspirin is available over the counter (OTC).
Alan P. Jacobsen +13 more
doaj +1 more source
Aspirin-dependent effects on purinergic P2Y1 receptor express [PDF]
, 2019 Chronic treatment with aspirin in healthy volunteers (HVs) is associated with recovery of adenosine diphosphate (ADP)-induced platelet activation. The purinergic P2Y1 receptor exerts its effects via a Gq-protein, which is the same biochemical pathway ...
Alemanno, Laura +8 more
core +1 more source
Journal of Clinical and Translational Science, 2023 OBJECTIVES/GOALS: Low-dose aspirin is an established treatment to prevent preeclampsia, a leading cause of maternal and perinatal complications. Nevertheless, aspirin failure is not uncommon.
Amihai Rottenstreich +2 more
doaj +1 more source
Aspirin in primary prevention of cardiovascular disease and cancer : a systematic review of the balance of evidence from reviews of randomized trials [PDF]
, 2013 Background: Aspirin has been recommended for primary prevention of cardiovascular disease (CVD) and cancer, but overall benefits are unclear. We aimed to use novel methods to re-evaluate the balance of benefits and harms of aspirin using evidence from
Clarke, Aileen +10 more
core +3 more sources
Effects of Aspirin and Prednisone on Platelet Function and Thromboxane Synthesis in Healthy Dogs
Frontiers in Veterinary Science, 2019 Glucocorticoid administration is a risk factor for thromboembolism in hypercoagulable dogs, and it is unknown if aspirin counteracts glucocorticoid-induced hypercoagulability. The objective was to determine the effects of sustained aspirin and prednisone
John M. Thomason +3 more
doaj +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Aspirin: yesterday, today, and tomorrow
Pediatria i Medycyna Rodzinna, 2014 Clinical utility of aspirin (acetylsalicylic acid, ASA) is one of the more important issues in the primary and secondary prevention of cardiovascular disease.
Marina Nikołajewna Dołżenko
doaj +1 more source