Results 141 to 150 of about 372,006 (379)

Bioengineering Strategies for Treating Neointimal Hyperplasia in Peripheral Vasculature: Innovations and Challenges

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John, Caitlyn Dang, Nidhi Reddy, Calvin Chao, Karen J. Ho, Bin Jiang   +5 more
wiley   +1 more source

MDR1 is Related to Intestinal Epithelial Injury Induced by Acetylsalicylic Acid

Cellular Physiology and Biochemistry, 2013
Background/Aims: Although the cytotoxicity of aspirin against the intestinal epithelium is a major clinical problem, little is known about its pathogenesis. We assessed the involvement of Multi Drug Resistance (MDR) 1 in intestinal epithelial cell injury
Munehiro Kugai, Kazuhiko Uchiyama, Toshifumi Tsuji, Hiroyuki Yoriki, Akifumi Fukui, Ying Qin, Yasuki Higashimura, Katsura Mizushima, Naohisa Yoshida, Kazuhiro Katada, Kazuhiro Kamada, Osamu Handa, Tomohisa Takagi, Hideyuki Konishi, Nobuaki Yagi, Toshikazu Yoshikawa, Yoshiyuki Shirasaka, Ikumi Tamai, Yuji Naito, Yoshito Itoh   +19 more
doaj   +1 more source

Bioprinted Micro‐Clots for Kinetic Analysis of Endothelial Cell‐Mediated Fibrinolysis

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This paper describes the development of a microscale model that quantifies the breakdown of fibrin by endothelial cells. The small size scale of this engineered system enables fibrin breakdown to be observed without the addition of external activators. This system could help in identifying compounds which both promote and hinder thrombosis.
Jonathan J. Chang, Kelsey Brew, Jamie A.G. Hamilton, Varun Kumar, José A. Diaz, Shuichi Takayama   +5 more
wiley   +1 more source

Prevention is better than cure, but...: Preventive medication as a risk to ordinariness? [PDF]

, 2011
Preventive health remains at the forefront of public health concerns; recent initiatives, such as the NHS health check, may lead to recommendations for medication in response to the identification of 'at risk' individuals. Little is known about lay views
Adams S., Backett K., Benson J., Blaxter M., Bosely S., Britten N., Brown S. R., Catherine M. Will, Charmaz K., Cornwell J., Crawford R., Davison C., Davison C., Davison C., Fowkes F. G.R., Greco M., Griffiths F., Hallowell N., Hansen D. L., Hansen D. L., Heald C., Helen C. Eborall, Lumme-Sandt K., Lumme-Sandt K., Lupton D., Mills C. W., Moen J., Murphy E., Nettleton S., Novas C., Nørreslet M., Pound P., Radley A., Rose N., Rothwell P. M., Sachs L., Strauss A., Weiner K., Will C.   +38 more
core   +1 more source

Weitere klinische Erfahrungen über Aspirin [PDF]

, 1900
Herm. Liesau
openalex   +1 more source

Aspirin and gastric bleeding. [PDF]

, 1967
J. M. Bone
  +6 more sources

Morphometric‐Assisted Prediction of Developmental Toxicity Using Stem Cell‐Based Embryo Models in Microwells

Advanced Healthcare Materials, EarlyView.
This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar, Athanasia Zoi Pappa, Clemens van Blitterswijk, Erik Vrij, Stefan Giselbrecht   +4 more
wiley   +1 more source

Prevention of venous thromboembolism after hip and knee replacement among older adults [PDF]

, 2017
BACKGROUND: Venous thromboembolism (VTE) after total hip and knee replacement is a major patient safety threat, and pharmacologic prophylaxis is generally recommended. However, clinicians disagree on the optimal prophylaxis agent.
Ko, Darae
core  

Platelet isoprostane overproduction in diabetic patients treated with aspirin [PDF]

, 2012
Aspirin modestly influences cardiovascular events in patients with type 2 diabetes mellitus (T2DM), but the reason is unclear. The aim of the study was to determine whether in T2DM patients aspirin enhances platelet isoprostanes, which are eicosanoids ...
Angelico, F, Basili, S, Cangemi, R, Carnevale, R, Lauro, D, Nigro, C, Pignatelli, P, Proietti, M, Violi, F   +8 more
core   +2 more sources

Study of Entropy-Driven Polymorphic Stability for Aspirin Using Accurate Neural Network Interatomic Potential [PDF]

arXiv
In this study, we present a systematic computational investigation to analyze the long debated crystal stability of two well known aspirin polymorphs, labeled as Form I and Form II. Specifically, we developed a strategy to collect training configurations covering diverse interatomic interactions between representative functional groups in the aspirin ...
arxiv