Results 141 to 150 of about 312,145 (352)

Silencing Myostatin Using In Vivo Self‐Assembled siRNA Protects Against Cancer‐ and Dexamethasone‐Induced Muscle Atrophy

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin   +14 more
wiley   +1 more source

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

open access: yesAdvanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen   +7 more
wiley   +1 more source

Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia

open access: yesNew England Journal of Medicine, 2017
D. Rolnik   +19 more
semanticscholar   +1 more source

Harnessing Synergistic Cooperation of Neighboring Active Motifs in Heterogeneous Catalysts for Enhanced Catalytic Performance

open access: yesAdvanced Materials, EarlyView.
This review examines the critical role of neighboring active motifs in heterogeneous catalysts, emphasizing how their synergistic cooperativity can be rationally designed to modulate catalytic properties. The discussion centers on the modulation of electronic and geometric structures, categorizing the catalytic systems into metal‐acid (Brønsted/Lewis ...
Peng Yuan   +2 more
wiley   +1 more source

EFFECTS OF ASPIRIN AND PHENYLBUTAZONE ON THE RABBIT BLASTOCYST [PDF]

open access: bronze, 1965
James L. Schardein   +3 more
openalex   +1 more source

Advancing Self‐Assembled Molecules Toward Interface‐Optimized Perovskite Solar Cells: from One to Two

open access: yesAdvanced Materials, EarlyView.
In the past few years, self‐assembled molecules (SAMs) have ushered in a new era of interface engineering for perovskite solar cells. Herein, the recent progresses of co‐SAM, namely two SAMs with synergy, are comprehensively summarized and analyzed, focusing on topics including deposition methods and design principles, while further challenges about ...
Tanghao Liu   +6 more
wiley   +1 more source

Recent Advances in Heterogeneous Frustrated Lewis Pair: Synthesis, Characterization, and Catalysis

open access: yesAdvanced Materials, EarlyView.
This review provides a concise analysis of heterogeneous frustrated Lewis pair (FLP) chemistry, focusing on their synthesis, characterization, and application in small‐molecule activation. It highlights current challenges in developing solid FLP systems and explores promising advancements through emerging technologies, offering critical insights into ...
Jiasi Li   +2 more
wiley   +1 more source

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