Results 171 to 180 of about 312,145 (352)

Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity

Advanced Science, EarlyView.
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong, Lin‐Lin Hu, Ling Jiang, Pei‐Xia Shi, Shuang Zhang, Yuan Zhao, Bing‐Qiao Wang, Xiao‐Feng Cheng, Cheng‐Kang He, Sen Lin, Yue Dai, Zhao‐You Meng, Chen‐Hao Zhao, Bao‐Liang Sun, Qi Xie, Fang‐Fei Li, Qing‐Wu Yang   +16 more
wiley   +1 more source

Effect of aspirin on grip strength and gait speed in community-dwelling older adults in the ASPirin in Reducing Events in the Elderly (ASPREE) Study. [PDF]

J Gerontol A Biol Sci Med Sci
Phyo AZZ, Espinoza SE, Orchard SG, Wolfe R, Murray AM, Woods RL, Ryan J.   +6 more
europepmc   +1 more source

ASPIRIN

, 1965
Gerhard Levy
openalex   +1 more source

Erratum to: In vitro evaluation physiological availability of aspirin tablets [PDF]

, 1970
Owen I. Corrigan, R. F. Timoney
openalex   +1 more source

Reprogramming of Fatty Acid Metabolism via PPARα‐Orchestrated FADS2 in Keratinocytes Modulates Skin Inflammation in Psoriasis

Advanced Science, EarlyView.
This study identifies fatty acid desaturase 2 (FADS2) as a key regulator linking polyunsaturated fatty acid (PUFA) metabolism to psoriatic inflammation. FADS2 deficiency impairs docosahexaenoic acid (DHA) biosynthesis, enhances NF‐κB signaling, and promotes neutrophil‐driven skin inflammation. PPARα transcriptionally activates FADS2, and its activation
Jiangluyi Cai, Xue Zhou, Yu Zhuang, Lian Cui, Rui Ma, Youdong Chen, Nan Yang, Qianyu Chen, Yuanyuan Wang, Peiyao Zhu, Lingling Yao, Qian Yu, Xiaomin She, Xuyang Zhou, Yuemeng Huang, Zengyang Yu, Xilin Zhang, Jiajing Lu, Yuling Shi, Chunyuan Guo   +19 more
wiley   +1 more source

Nasal Epithelial Extracellular Vesicles Correlate with Type 2 Inflammation during Aspirin-induced Respiratory Reactions. [PDF]

Am J Respir Cell Mol Biol
Bunn KE, Bressman ZJ, Nation GK, Wu P, Amin T, Lehman C, Lin A, Gray CJ, Laidlaw TM, Cahill KN, Pua HH.   +10 more
europepmc   +1 more source

Effect of aspirin on intestinal absorption of glucose, sodium, and water in man. [PDF]

, 1977
Constantine Arvanitakis, Guanhua Chen, J. Folscroft, N. J. Greenberger   +3 more
openalex   +1 more source

Role of aspirin in cancer prevention.

Cancer Treatment and Research Communications
Meng Sun, Jun Yu, Jie Wan, Xiaoyun Dou, Xiaoying Chen, Fang Ye   +5 more
semanticscholar   +1 more source

Rivaroxaban or Aspirin for Extended Treatment of Venous Thromboembolism

New England Journal of Medicine, 2017
J. Weitz, A. Lensing, M. Prins, R. Bauersachs, J. Beyer-Westendorf, H. Bounameaux, T. Brighton, A. Cohen, B. Davidson, H. Décousus, M. S. Freitas, G. Holberg, Ajay Kakkar, L. Haskell, B. van Bellen, Á. Pap, S. Berkowitz, P. Verhamme, P. Wells, P. Prandoni   +19 more
semanticscholar   +1 more source

Single‐Cell RNA Sequencing Reveals the Heterogeneity in Differentiation Trajectory and Tumor Microenvironment Leading to More Aggressive Phenotypes of Papillary Thyroid Cancer in Children and Young Adult Patients

Advanced Science, EarlyView.
scRNA sequencing reveals distinct tumor ecosystem features in CAYA‐PTC, marked by enriched CD4T_Tfh, CD8T_Tex cells, and rapid malignant thyrocyte differentiation (absent of mild‐state BRAF‐like population) toward invasive states. Prominent emCAF_LAMP5 populations interact with endothelial cells and thyrocytes facilitate angiogenesis and metastasis ...
Kai Guo, Lingyi Yang, Zirui Huang, Kai Qian, Yuan Shi, Mengjia Fei, Yuan Feng, Zixian Chen, Ming Qiu, Linglin Tang, Anqi Li, Zhibao Lv, Jiangbin Liu, Zhou Chen, Kuiran Dong, Zhuoying Wang   +15 more
wiley   +1 more source