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Aspirin or acetylsalicylic acid (ASA) is still one of the most widely sold drugs in the world and its side effects are well known. Among these, hypersensitivity reactions represent one of the most frequently described since the first report of urticaria and angio-oedema by Hirshberg in 1902.1 The hypersensitivity reactions to aspirin may be divided ...
Nucera, Eleonora+6 more
openaire +5 more sources
Preeclampsia (PE) is a multisystem disorder that is an important cause of maternal and perinatal deaths. Currently, delivery is the only final treatment for PE. This practice is usually accompanied by premature birth, which inevitably increases neonatal morbidities.
Tae Gyu Ahn, Jong Yun Hwang
openaire +3 more sources
Mechanistic view into the therapeutic effect, anticancer potential and the adverse effect of aspirin [PDF]
In this research, the working mechanism behind the therapeutic effect of aspirin will be discussed in detail. Aspirin will also be assessed as a promising drug to treat cancerous cells in the future.
Ouyang Juan
doaj +1 more source
Aspirin and the Primary Prevention of Cardiovascular Diseases. An Approach Based on Individualized, Integrated Estimation of Risk [PDF]
While the use of aspirin in the secondary prevention of cardiovascular (CVD) is well established, aspirin in primary prevention is not systematically recommended because the absolute CV event reduction is similar to the absolute excess in major bleedings.
Battistoni, Allegra+4 more
core +1 more source
Background Aspirin has been found to lower the occurrence rates of some cancers through the inhibition of the cyclooxygenase enzyme. For example, there is a well-known association between aspirin use and the occurrence of hepatocellular carcinoma (HCC ...
Yen-Hsiang Liao+8 more
doaj +1 more source
Nasal lysine aspirin challenge in the diagnosis of aspirin - exacerbated respiratory disease [PDF]
Background Aspirin-exacerbated respiratory disease is under-diagnosed and therefore effective and inexpensive therapy with aspirin desensitization is rarely performed.
Darby, Y+6 more
core +1 more source
Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease
BACKGROUND We evaluated whether rivaroxaban alone or in combination with aspirin would be more effective than aspirin alone for secondary cardiovascular prevention.
J. Eikelboom+48 more
semanticscholar +1 more source
Lower mortality rate in elderly patients with community-onset pneumonia on treatment with aspirin [PDF]
BACKGROUND: Pneumonia is complicated by high rate of mortality and cardiovascular events (CVEs). The potential benefit of aspirin, which lowers platelet aggregation by inhibition of thromboxane A2 production, is still unclear. The aim of the study was to
Barilla', Francesco+11 more
core +1 more source
Aspirin-dependent effects on purinergic P2Y1 receptor express [PDF]
Chronic treatment with aspirin in healthy volunteers (HVs) is associated with recovery of adenosine diphosphate (ADP)-induced platelet activation. The purinergic P2Y1 receptor exerts its effects via a Gq-protein, which is the same biochemical pathway ...
Alemanno, Laura+8 more
core +1 more source
Is clopidogrel better than aspirin following breakthrough strokes while on aspirin? A retrospective cohort study. [PDF]
ObjectiveThere is insufficient evidence on which to base a recommendation for optimal antiplatelet therapy following a stroke while on aspirin. The objective was to compare clopidogrel initiation vs aspirin reinitiation for vascular risk reduction among ...
Chang, Ku-Chou+10 more
core +1 more source