A hidden cause of infertility in hypothyroid patients [PDF]
, 2020 Methylene tetrahydrofolate reductase (MTHFR) gene mutations could be the cause of infertility in hypothyroid patients. Hence, it is worthy to screen for MTHFR gene mutations in infertile hypothyroid females and their partners if infertility persists ...
Ahmed, Soha Magdy +4 more
core +1 more source
The prognostic utility of tests of platelet function for the detection of 'aspirin resistance' in patients with established cardiovascular or cerebrovascular disease: a systematic review and economic evaluation. [PDF]
, 2015 BACKGROUND: The use of aspirin is well established for secondary prevention of cardiovascular disease. However, a proportion of patients suffer repeat cardiovascular events despite being prescribed aspirin treatment.
Bayliss, S +12 more
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Aspirin Resistance in Patients Undergoing Hemodialysis and Effect of Hemodialysis on Aspirin Resistance [PDF]
Clinical and Applied Thrombosis/Hemostasis, 2013 The aim of this study was to evaluate the prevalence of aspirin resistance (AR) in patients undergoing hemodialysis (HD) and to assess the effect of HD on the results of the Multiplate test. A total of 54 patients undergoing HD were included in this study. Blood samples were taken just before and after the HD session.
Nevzat Uslu +9 more
openaire +2 more sources
Journal of Translational Medicine, 2008 Background Our previous publication showed that 9% of patients with a history of myocardial infarction MI. could be labeled as aspirin resistant; all of these patients were aspirin resistant because of non-compliance.
Reeves Mathew +4 more
doaj +1 more source
Pharmacogenetics : the science of predictive clinical pharmacology [PDF]
, 2014 The study of pharmacogenetics has expanded from what were initially casual family-based clinical drug response observations, to a fully-fledged science with direct therapeutic applications, all within a time-span of less than 60 years. A wide spectrum of
Fenech, Anthony G., Grech, Godfrey
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CLINICAL SIGNIFICANCE OF ASPIRIN RESISTANCE IN PATIENTS WITH CARDIO-VASCULAR DISEASES
Рациональная фармакотерапия в кардиологии, 2016 Atherothrombosis is a complication of ischemic heart disease, and it leads to development of acute coronary syndrome. Atherothrombosis is characterized by sudden destruction of atherosclerotic plaque, which results into platelets activation and thrombus ...
P. J. Dovgalevsky +2 more
doaj +1 more source
Aspirin and Clopidogrel Resistance
Hematology, 2007 AbstractAspirin and clopidogrel provide significant clinical benefit in patients with cardiovascular disease. However, given the complexity of platelet activation, it is not surprising that aspirin or clopidogrel prevent a small proportion of cardiovascular events.
Desmond J. Fitzgerald, Andrew O. Maree
openaire +3 more sources
Pharmaceutics, 2022 Introduction: Aspirin resistance may be associated with various conditions. We measured serum thromboxane B2 (TXB2) and platelet function using the Multiplate® Analyzer with arachidonic acid (ASPI) in patients on long term aspirin therapy to identify ...
Weiwei Zeng +7 more
doaj +1 more source
Biochemical aspirin resistance in stroke patients: a cross-sectional single centre study [PDF]
, 2013 Background: Aspirin use is known to reduce the recurrence of stroke. However, the clinical response to aspirin has been mixed. The rate of stroke recurrence whilst on aspirin treatment is still unacceptably high.
Ali, Raymond Azman +8 more
core
Nasal lysine aspirin challenge in the diagnosis of aspirin - exacerbated respiratory disease [PDF]
, 2013 Background Aspirin-exacerbated respiratory disease is under-diagnosed and therefore effective and inexpensive therapy with aspirin desensitization is rarely performed.
Darby, Y +6 more
core +1 more source