Results 51 to 60 of about 88,050 (335)

Aspirin “allergy” and resistance

Journal of the American College of Cardiology, 2004
In a recent article, Gum et al.([1][1]) discussed aspirin resistance, and Eikelboom et al. ([2][2]) wrote an editorial comment regarding this topic. We have seen several patients who reported that they seemed to have “allergic” reactions to aspirin.
Selina Akhter, Julian L. Ambrus, Clara M. Ambrus   +2 more
openaire   +2 more sources

Biochemical aspirin resistance in stroke patients: a cross-sectional single centre study [PDF]

, 2013
Background: Aspirin use is known to reduce the recurrence of stroke. However, the clinical response to aspirin has been mixed. The rate of stroke recurrence whilst on aspirin treatment is still unacceptably high.
Ali, Raymond Azman, Basri, Hamidon, Md. Rani, Shahrul Azmin, Mohamed Ibrahim, Norlinah, Remli, Rabani, Sahathevan, Ramesh, Shah, Shamsul Azhar, Tan, Hui Jan, Wan Yahya, Wan Nur Nafisah   +8 more
core  

Nasal lysine aspirin challenge in the diagnosis of aspirin - exacerbated respiratory disease [PDF]

, 2013
Background Aspirin-exacerbated respiratory disease is under-diagnosed and therefore effective and inexpensive therapy with aspirin desensitization is rarely performed.
Darby, Y, Gane, S, Larco, J, Miller, B, Mirakian, R, Sannah, AA, Scadding, G   +6 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Aspirin strategy for secondary prevention of atherosclerotic cardiovascular diseases: A narrative review

Journal of the Practice of Cardiovascular Sciences, 2023
Aspirin is the most used antiplatelet agent for secondary prophylaxis of atherosclerotic cardiovascular diseases. Individual variability in aspirin responsiveness has been widely reported.
Nischal N Hegde, Navin Mathew
doaj   +1 more source

Aspirin Resistance in Hypertensive Patients [PDF]

The Journal of Clinical Hypertension, 2010
J Clin Hypertens (Greenwich). 2010;12:714–720. ©2010 Wiley Periodicals, Inc.Aspirin resistance is associated with poor clinical prognosis. The authors investigated aspirin resistance in 200 hypertensive patients (111 men, age: 68.3±11.4 years) by the Ultegra Rapid Platelet Function Assay‐ASA (Accumetrics Inc., San Diego, CA).
Beste Ozben, Azra Meryem Tanrikulu, Oguz Caymaz, Tomris Ozben   +3 more
openaire   +4 more sources

Effect of Opium Addiction on Aspirin Resistance in Stable Angina Pectoris [PDF]

, 1949
Background: The rate of cardiovascular diseases in developing countries is approximately 60% and it is still has an increasing trend. The clinical effectiveness of aspirin in preventing cardiovascular events has been well proven.
Afsaneh Forood MD1, Reza Malekpour-Afshar MD2,,, Jamshid Sarnevesht MD3,   +1 more
core  

Plasma inflammatory cytokines and survival of pancreatic cancer patients. [PDF]

, 2018
OBJECTIVES: Inflammation and inflammatory conditions have been associated with pancreatic cancer risk and progression in a number of clinical, epidemiological, and animal model studies.
Babic, A., Barbie, D. A., Brais, L. K., Fuchs, C. S., Kulke, M. H., Morales-Oyarvide, V., Neupane, N. P., Ng, K., Poole, E. M., Rifai, N., Rubinson, D. A., Schnure, N., Welch, M. W., Wolpin, B. M., Wong, K., Yuan, C., Zaman, M. M., Zhang, S.   +17 more
core   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source