Results 51 to 60 of about 9,312 (200)

General measures in the treatment of sickle cell disease [PDF]

, 2007
This article presents the most important measures in the care of patients with sickle cell disease, which is characterized by a high morbimortality rate.
Braga, Josefina Aparecida Pellegrini
core   +3 more sources

Integrating Chain‐of‐Thought and Retrieval Augmented Generation Enhances Rare Disease Diagnosis From Clinical Notes

Medicine Bulletin, Volume 2, Issue 2, Page 167-183, March 2026.
ABSTRACT Background Several studies show that large language models (LLMs) struggle with phenotype‐driven gene prioritization for rare diseases. These studies typically use Human Phenotype Ontology (HPO) terms to prompt foundation models such as GPT and LLaMA to predict candidate genes.
Zhanliang Wang, Da Wu, Quan Nguyen, Kai Wang   +3 more
wiley   +1 more source

Novel Targeting to XCR1+ Dendritic Cells Using Allogeneic T Cells for Polytopical Antibody Responses in the Lymph Nodes

Frontiers in Immunology, 2019
Vaccination strategy that induce efficient antibody responses polytopically in most lymph nodes (LNs) against infections has not been established yet.
Yusuke Kitazawa, Hisashi Ueta, Yasushi Sawanobori, Tomoya Katakai, Hiroyuki Yoneyama, Satoshi Ueha, Kouji Matsushima, Nobuko Tokuda, Kenjiro Matsuno   +8 more
doaj   +1 more source

Impact of pneumococcal conjugate vaccination: a retrospective study of hospitalization for pneumonia in North-East Italy [PDF]

, 2016
Introduction. Pneumonia remains a common reason for hospitalizing infants and the elderly worldwide, and streptococcal infection is often responsible. The aim of this study was to assess the burden of pneumonia in a large general population. Methods. All
Baldo, Vincenzo, Baldovin, Tatjana, Bertoncello, Chiara, Buja, Alessandra, Clagnan, E, Cocchio, Silvia, Del Zotto, S, Furlan, Patrizia, Gallo, T, Saia, Mario   +9 more
core   +1 more source

European Society for the Study of Coeliac Disease (ESsCD) 2025 Updated Guidelines on the Diagnosis and Management of Coeliac Disease in Adults. Part 2: Management, Follow‐Up, and Complex Disease Courses

United European Gastroenterology Journal, Volume 14, Issue 2, March 2026.
ABSTRACT Introduction Since the publication of the first European Society for the Study of Coeliac Disease (ESsCD) guidelines in 2019, substantial advances have been made in understanding the management and complex disease courses of coeliac disease (CeD) in adults.
Abdulbaqi Al‐Toma, Federica Branchi, Fabiana Zingone, Annalisa Schiepatti, Georgia Malamut, Cristina Canova, Isabella Rosato, Honoria Ocagli, Nick Trott, Luca Elli, Alina Popp, Carmen Gianfrani, Renata Auricchio, Andra Neefjes‐Borst, David S. Sanders, Christophe Cellier, Chris J. Mulder, Gerd Bouma, Knut E. A. Lundin, Ludvig M. Sollid, Michael Schumann   +20 more
wiley   +1 more source

Travel advice for the immunocompromised traveler: prophylaxis, vaccination, and other preventive measures [PDF]

, 2015
Immunocompromised patients are traveling at increasing rates. Physicians caring for these complex patients must be knowledgeable in pretravel consultation and recognize when referral to an infectious disease specialist is warranted. This article outlines
Koolwal, Pooja, Kuhlmann, Frederick Matthew, Liang, Stephen Y, Patel, Rupa R   +3 more
core   +2 more sources

Incidence of RSV‐ and Influenza‐Associated Hospitalizations With Community‐Acquired Pneumonia and Other Acute Respiratory Infection Among Adults in Japan in 2022–2024: APSG‐J2 Study

Influenza and Other Respiratory Viruses, Volume 20, Issue 3, March 2026.
ABSTRACT Background Quantifying the burden of respiratory syncytial virus (RSV) in adults is challenging compared to influenza, and data among older adults remain scarce in Japan. Country‐specific evidence is essential to support RSV vaccination policy.
Haruka Maeda, Shingo Masuda, Bhim Gopal Dhoubhadel, Yuka Fujita, Yuji Akiba, Yutaka Nishigaki, Kei Nakashima, Hiroyuki Ito, Masayuki Nogi, Yoshihito Otsuka, Masayuki Ishida, Eiji Takeuchi, Norichika Asoh, Toyomitsu Sawai, Koichi Hayakawa, Eileen M. Dunne, Claudia Schwarz, Bradford D. Gessner, Elizabeth Begier, Shuhei Ito, Ataru Igarashi, Shinobu Osanai, Konosuke Morimoto, Koya Ariyoshi, Adult Pneumonia Study Group‐Japan 2 (APSG‐J2)   +24 more
wiley   +1 more source

Expert Perspectives on the Vaccination of Individuals Who Are at Increased Risk of Meningococcal Disease Due to Medical Conditions: A Podcast

Infectious Diseases and Therapy, 2023
Patients with functional or anatomic asplenia, including sickle cell anemia; complement component deficiency; or human immunodeficiency virus (HIV) infection have a significantly increased risk of developing meningococcal disease.
Oscar Herrera-Restrepo, Diana E. Clements, Wanda J. Conley, Gary S. Marshall   +3 more
doaj   +1 more source

Laparoscopic Partial Splenectomy for a Giant Congenital Splenic Cyst in a Child: Case Report and Focused Literature Review

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT An 11‐year‐old boy with a 16 × 14.5 cm congenital splenic cyst underwent laparoscopic upper‐pole partial splenectomy after negative hydatid workup and vaccination. Recovery was uneventful; histology confirmed epithelial cyst. Spleen‐preserving surgery provided durable symptom relief and preserved function.
Ahmed Alanzi, Dawood Alatefi, Malik Alkabazi, Bano Alsaleh, Khaled M. AlAani, Samah Hakmi   +5 more
wiley   +1 more source

Impact of a spleen registry on optimal post-splenectomy vaccination and care

Human Vaccines & Immunotherapeutics, 2018
Objective: To evaluate quality of patient knowledge and rates of adherence to guidelines amongst splenectomised patients registered to the Spleen Australia registry.
Sarah Luu, Claire Dendle, Penelope Jones, Samar Ojaimi, Ian J. Woolley   +4 more
doaj   +1 more source