Results 51 to 60 of about 6,451 (194)

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, Volume 78, Issue 10, Page 1449-1466, October 2026.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

Chest radiographic findings in children with asplenia syndrome

, 2010
Background: Early diagnosis of asplenia syndrome is important because prophylactic antibiotic and proper vaccination will prevent serious infection. Most children with asplenia syndrome present with symptoms of congenital heart disease.
Kullana Tantiprawan, Panruethai Trinavarat, Apichai Khongphatthanayothin   +2 more
core   +1 more source

Impact of a spleen registry on optimal post-splenectomy vaccination and care

Human Vaccines & Immunotherapeutics, 2018
Objective: To evaluate quality of patient knowledge and rates of adherence to guidelines amongst splenectomised patients registered to the Spleen Australia registry.
Sarah Luu, Claire Dendle, Penelope Jones, Samar Ojaimi, Ian J. Woolley   +4 more
doaj   +1 more source

Expert Perspectives on the Vaccination of Individuals Who Are at Increased Risk of Meningococcal Disease Due to Medical Conditions: A Podcast

Infectious Diseases and Therapy, 2023
Patients with functional or anatomic asplenia, including sickle cell anemia; complement component deficiency; or human immunodeficiency virus (HIV) infection have a significantly increased risk of developing meningococcal disease.
Oscar Herrera-Restrepo, Diana E. Clements, Wanda J. Conley, Gary S. Marshall   +3 more
doaj   +1 more source

Laparoscopic Splenectomy for a Completely Infarcted Wandering Spleen After Prolonged Positional Abdominal Pain: A Case Report and Focused Literature Review

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 19‐year‐old woman had a 7–8‐year history of positional abdominal pain, a mobile mass and transient thrombocytopenia. Computed tomography showed a completely infarcted wandering spleen with pedicle torsion. Fully laparoscopic splenectomy succeeded despite total infarction.
Toufic Awwad, Ahmad Jradi, Riwa Deghaim, Mohamad Khalife   +3 more
wiley   +1 more source

Pneumococcal purpura fulminans in asplenic or hyposplenic patients: a French multicenter exposed-unexposed retrospective cohort study

Critical Care, 2020
Background Pneumococcal infections remain the main cause of overwhelming post-splenectomy infections, and purpura fulminans may develop in almost 20% of patients with overwhelming post-splenectomy infection.
Damien Contou, Rémi Coudroy, Gwenhaël Colin, Jean-Marc Tadié, Martin Cour, Romain Sonneville, Armand Mekontso Dessap, Nicolas de Prost, for the HOPEFUL Study Group   +8 more
doaj   +1 more source

Cracking the cytokine code in sickle cell disease: Immune‐informatics for precision inflammation mapping, risk prediction and therapeutic discovery

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Sickle cell disease inflammation emerges from interconnected cytokine networks. Immune‐informatics integrates multi‐omics, network biology and artificial intelligence to decode inflammatory signatures, predict complications and identify precision therapeutic targets. Abstract Background Sickle cell disease (SCD) is characterised by chronic inflammation
Emmanuel Ifeanyi Obeagu, Chukwuma J. Okafor   +1 more
wiley   +1 more source

Vaccinations in Pediatric Hematology and Oncology: Biologic Basis, Clinical Applications, and Perspectives

Vaccines
Children with hemato-oncological diseases represent a heterogeneous population at heightened risk for vaccine-preventable diseases. Their immunosuppressed state reduces vaccine efficacy and raises safety concerns regarding live attenuated vaccines due to
Baldassarre Martire, Alessandra Beni, Maria Felicia Mastrototaro, Veronica Santilli, Giorgio Ottaviano, Davide Montin, Caterina Rizzo, Mayla Sgrulletti, Michele Miraglia del Giudice, Giorgio Costagliola, Viviana Moschese   +10 more
doaj   +1 more source

Heme oxygenase-1 deficiency presenting with interstitial lung disease and hemophagocytic flares

Pediatric Rheumatology Online Journal, 2020
Background Heme oxygenase-1 (HMOX1) catalyzes the metabolism of heme into carbon monoxide, ferrous iron, and biliverdin. Through biliverdin reductase, biliverdin becomes bilirubin.
Alice S. Chau, Bonnie L. Cole, Jason S. Debley, Kabita Nanda, Aaron B. I. Rosen, Michael J. Bamshad, Deborah A. Nickerson, Troy R. Torgerson, Eric J. Allenspach   +8 more
doaj   +1 more source

EHA Guidelines on the management of children and adults with hemoglobin SC disease

HemaSphere, Volume 10, Issue 10, October 2026.
Abstract HbSC disease is the second most common type of sickle cell disease (SCD) in populations of African origin. Although it is often grouped together with other types of SCD, particularly sickle cell anemia (HbSS), it has unique pathophysiology and a different spectrum of laboratory and clinical features.
David C. Rees, Valentine Brousse, Mariane de Montalembert, Bart J. Biemond, Lucia De Franceschi, Eugene Oteng‐Ntim, Pagona Flevari, Valeria Pinto, John James, Elena Cela, Stefan Eber, Rachel Kesse‐Adu, Jennifer Knight‐Madden, France Pirenne, Aline Santin, Andreas Glenthøj   +15 more
wiley   +1 more source