Results 21 to 30 of about 4,614,031 (312)

Adult Male Hypogonadism: A Laboratory Medicine Perspective on Its Diagnosis and Management

Diagnostics, 2023
Testosterone (T), the principal androgen secreted by the testes, plays an essential role in male health. Male hypogonadism is diagnosed based on a combination of associated clinical signs and symptoms and laboratory confirmation of low circulating T ...
Mark Livingston, Adrian H. Heald
doaj   +1 more source

Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]

, 2017
Introduction: Measurement of thrombolytic activity i.e. clot lysis is crucial for research and development of novel thrombolytics. It is also a key factor in assessment of the effectiveness of conventionally used thrombolytic agents in the clinic, which ...
Entekhabi, Nazila, Eskandani, Morteza, Farhoudi, Mehdi, Mohammadian, Reza, Rafi, Mohammad, Zamanlu, Masumeh   +5 more
core   +2 more sources

tmRNA - a novel high-copy-number RNA diagnostic target - its application for Staphylococcus aureus detection using real-time NASBA [PDF]

, 2009
A real-time nucleic acid sequence-based amplification assay, targeting tmRNA, was designed for the rapid identification of Staphylococcus aureus. The selectivity of the assay was confirmed against a panel of 76 Staphylococcus strains and species and 22 ...
Anonymous, Anonymous, Anonymous, Anonymous, Barry Glynn, Justin O'Grady, Katrina Lacey, Majella Maher, Terry J. Smith, Thomas Barry   +9 more
core   +1 more source

The Content and Size of Hyaluronan in Biological Fluids and Tissues

Frontiers in Immunology, 2015
Hyaluronan is a simple repeating disaccharide polymer, synthesized at the cell surface by integral membrane synthases. The repeating sequence is perfectly homogeneous, and is the same in all vertebrate tissues and fluids.
Mary K. Cowman, Hong-Gee eLee, Kathryn L. Schwertfeger, James B. McCarthy, Eva A. Turley   +4 more
doaj   +1 more source

Evaluation of Host Protein Biomarkers by ELISA From Whole Lysed Peripheral Blood for Development of Diagnostic Tests for Active Tuberculosis

Frontiers in Immunology, 2022
Tuberculosis (TB) remains a significant global health crisis and the number one cause of death for an infectious disease. The health consequences in high-burden countries are significant.
Harriet N. Garlant, Kalaiarasan Ellappan, Matthew Hewitt, Prem Perumal, Simon Pekeleke, Nadina Wand, Jo Southern, Saka Vinod Kumar, Harish Belgode, Ibrahim Abubakar, Sanjeev Sinha, Seshadri Vasan, Noyal Mariya Joseph, Karen E. Kempsell   +13 more
doaj   +1 more source

Evaluation of the first automated thyroglobulin assay [PDF]

, 1999
The aim of this study was to investigate technical and analytical performance of the first automated thyroglobulin (Tg) assay (DPC-Immulite(R); Diagnostic Products Corporation, Los Angeles, USA).
Bland JM, Dai J, Feldt-Rasmussen U, Feldt-Rasmussen U, Knadler L, Marquet PY, Niederau CM, Passing H, Roelants V, Spencer CA, Zucchelli GC   +10 more
core   +1 more source

Paratope plasticity determines anti-HER2 (4B5) antibody specificity

mAbs
The PATHWAY anti-HER2/neu (4B5) Rabbit Monoclonal Primary Antibody immunohistochemistry (IHC) assay is used to identify patients eligible for anti-HER2 targeted therapy.
P. Daniel Warren, Terry H. Landowski, Mark S. Dodson, Adnan Gulzar, John D. Palting, Erika Walker, Penny Towne, Margaret H. Smith   +7 more
doaj   +1 more source

RefCNV: Identification of Gene-Based Copy Number Variants Using Whole Exome Sequencing

Cancer Informatics, 2016
With rapid advances in DNA sequencing technologies, whole exome sequencing (WES) has become a popular approach for detecting somatic mutations in oncology studies.
Lun-Ching Chang, Biswajit Das, Chih-Jian Lih, Han Si, Corinne E. Camalier, Paul M. McGregor, Eric Polley   +6 more
doaj   +1 more source

New Modalities of 3D Pluripotent Stem Cell-Based Assays in Cardiovascular Toxicity

Frontiers in Pharmacology, 2021
The substantial progress of the human induced pluripotent stem cell (hiPSC) technologies over the last decade has provided us with new opportunities for cardiovascular drug discovery, regenerative medicine, and disease modeling.
Barbara Orsolits, Zsófia Kovács, János Kriston-Vizi, Béla Merkely, Gábor Földes, Gábor Földes   +5 more
doaj   +1 more source

Evaluation of a research use only (RUO) TIMP-1 assay for use with the automated Alinity i platform

Biochemistry and Biophysics Reports
Tissue inhibitor of metalloproteinase-1 (TIMP-1) binds matrix metalloproteinases to regulate extracellular matrix turnover; elevated TIMP-1 has been associated with liver fibrosis, tumor progression, and fibrotic heart disease.
Mark Anderson, Jessica Grieshaber, Jose Ortiz, Mekhi Baclig, Gina Pacenti, Joseph Munoz, Christine Rudolph, Kathy Otis, Josie Corby, John Prostko, Philip Hemken   +10 more
doaj   +1 more source