Results 61 to 70 of about 3,944,654 (298)
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Developmental divergence of sensory stimulus representation in cortical interneurons
Sensory neuronal circuits adapt during maturation when animals start to actively interact with the external world. The authors reveal structural and functional rearrangements of the input cortical interneurons receive around the time the animals start ...
Rahel Kastli +9 more
doaj +1 more source
Shaft seal assembly for high speed and high pressure applications [PDF]
A seal assembly is provided for reducing the escape of fluids from between a housing and a shaft rotably mounted in the housing. The seal assembly comprises a pair of seal rings resiliently connected to each other and disposed in side-by-side ...
Hadt, W. F., Ludwig, L. P.
core +1 more source
We introduce and analyze the concept of an assembly map from the original homotopy theoretic point of view. We give also interpretations in terms of surgery theory, controlled topology and index theory. The motivation is that prominent conjectures of Farrell-Jones and Baum-Connes about K- and L-theory of group rings and group C^*-algebras predict that ...
openaire +2 more sources
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Colloidal particles equipped with platinum patches can establish chemical gradients in H _2 O _2 -enriched solutions and undergo self-propulsion due to local diffusiophoretic migration.
Kilian Dietrich +5 more
doaj +1 more source
Coupling device for moving vehicles [PDF]
A mechanical system is disclosed to capture and/or deploy a device or vehicle having relative motion with respect to another vehicle. The mechanism includes an onboard controlled collapsible iris assembly located at the end of a controlled manipulator ...
Rudmann, A. A.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Vogt-Koyanagi-Harada (VKH) disease recovery patterns remain inadequately characterized over extended periods. This study evaluated retinal changes in VKH patients across 5 years using adaptive optics imaging and microperimetry.
Tomoko Nakamura +3 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source

