Results 81 to 90 of about 4,209,255 (350)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
ThurGood: Evaluating Assembly-to-Assembly Mapping [PDF]
Journal of Computational Biology, 2004 The alignment and mapping of large genomic sequences is the focus of much recent research. However, relatively little has been done so far about testing and validating alignment methods. We introduce criteria and new tools we have developed for alignment evaluation. These tools have already proved useful in the evaluation and ranking of several methods
Hagit, Shatkay +5 more
openaire +2 more sources
Skin Health and DiseaseBackground Filaggrin‐2 (FLG2) and hornerin (HRNR) are members of the S100 fused‐type protein family, which share many properties with filaggrin (FLG). A previous study demonstrated that the expression of FLG2 was significantly decreased in psoriatic skin
Teruhiko Makino +4 more
doaj +1 more source
Approximate Self-Assembly of the Sierpinski Triangle
, 2010 The Tile Assembly Model is a Turing universal model that Winfree introduced in order to study the nanoscale self-assembly of complex (typically aperiodic) DNA crystals.
D. Soloveichik +4 more
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
, 1978 A valve assembly is reported for controlling the flow of fluids between the inlet and outlet of a fluid valve. The valve assembly contains a barrier element which is porous for providing fluid communication between the valve inlet and outlet.
Huber, W. C.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Annals of Gastroenterological SurgeryBackground There is no clear indication for surgery in pancreaticoduodenectomy (PD) for the elderly patients. The aim of this study was to use real‐world data to investigate the usefulness of preoperative risk assessment with the risk calculator ...
Nana Kimura +9 more
doaj +1 more source
Method and apparatus for deflection measurements using eddy current effects [PDF]
, 1993 A method and apparatus for inserting and moving a sensing assembly with a mechanical positioning assembly to a desired remote location of a surface of a specimen under test and measuring angle and/or deflection by sensing the change in the impedance of ...
Chern, Engmin J.
core +1 more source
Assembly and Disassembly Planning by using Fuzzy Logic & Genetic Algorithms
, 2004 The authors propose the implementation of hybrid Fuzzy Logic-Genetic Algorithm (FL-GA) methodology to plan the automatic assembly and disassembly sequence of products. The GA-Fuzzy Logic approach is implemented onto two levels.
Galantucci, L. M. +2 more
core +2 more sources