Results 81 to 90 of about 3,944,654 (298)

Effect of tumour necrotic factor‐α, interleukin‐17 and interleukin‐22 on the expression of filaggerin‐2 and hornerin: Analysis of a three‐dimensional psoriatic skin model

open access: yesSkin Health and Disease
Background Filaggrin‐2 (FLG2) and hornerin (HRNR) are members of the S100 fused‐type protein family, which share many properties with filaggrin (FLG). A previous study demonstrated that the expression of FLG2 was significantly decreased in psoriatic skin
Teruhiko Makino   +4 more
doaj   +1 more source

Fluid valve assembly [PDF]

open access: yes, 1978
A valve assembly is reported for controlling the flow of fluids between the inlet and outlet of a fluid valve. The valve assembly contains a barrier element which is porous for providing fluid communication between the valve inlet and outlet.
Huber, W. C.
core   +1 more source

Dualizing the coarse assembly map

open access: yes, 2004
We formulate and study a new coarse (co-)assembly map. It involves a modification of the Higson corona construction and produces a map dual in an appropriate sense to the standard coarse assembly map. The new assembly map is shown to be an isomorphism in
Emerson, Heath, Meyer, Ralf
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Risk Evaluation of the NCD Risk Calculator for Open Pancreaticoduodenectomy in Elderly Patients: A Validation Study

open access: yesAnnals of Gastroenterological Surgery
Background There is no clear indication for surgery in pancreaticoduodenectomy (PD) for the elderly patients. The aim of this study was to use real‐world data to investigate the usefulness of preoperative risk assessment with the risk calculator ...
Nana Kimura   +9 more
doaj   +1 more source

Pressurized lighting system [PDF]

open access: yes, 1973
Safe lighting assembly has been constructed for hostile environments. Assembly is ventilated by inert gas to prolong life of lamps. Lighting assembly contains control box, number of lamps connected in parallel, several pilot lights, and ventilating ...
Phlieger, G. A.
core   +1 more source

Approximate Self-Assembly of the Sierpinski Triangle

open access: yes, 2010
The Tile Assembly Model is a Turing universal model that Winfree introduced in order to study the nanoscale self-assembly of complex (typically aperiodic) DNA crystals.
D. Soloveichik   +4 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Cerulean: A hybrid assembly using high throughput short and long reads

open access: yes, 2013
Genome assembly using high throughput data with short reads, arguably, remains an unresolvable task in repetitive genomes, since when the length of a repeat exceeds the read length, it becomes difficult to unambiguously connect the flanking regions.
D.R. Zerbino   +14 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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