Results 81 to 90 of about 345,919 (279)
International Journal for Equity in Health, 2007 Background The pace of redressing inequities in the distribution of scarce health care resources in Namibia has been slow. This is due primarily to adherence to the historical incrementalist type of budgeting that has been used to allocate resources ...
Mutirua Kauto +5 more
doaj +1 more source
Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier
Advanced Science, EarlyView.SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao +11 more
wiley +1 more source
Portfolio design and management through state-based analytics: A probabilistic approach
Cogent Economics & Finance, 2020 This paper presents an innovative new approach to investment portfolio design, which applies a discrete, state-based methodology to defining market states and making asset allocation decisions with respect to both current and future state membership ...
Matthew W. Burkett +2 more
doaj +1 more source
Withdrawal Rates, Savings Rates, and Valuation-Based Asset Allocation [PDF]
While most everyone would agree that valuations matter, the question remains as to whether clients with a long-term outlook (such as those planning for retirement) can hope to act successfully on information about valuations.
Pfau, Wade Donald
core +1 more source
Advanced Science, EarlyView.Dendritic cells (DC) vaccine is an important type of vaccines. However, the limited efficacy of DC vaccines hinders their widely application. This study redefines DC vaccines and provides a new DC‐BC vaccine that have much better therapeutic efficacy.
Xiangxiang Xu +11 more
wiley +1 more source
A single-period model and some empirical evidences for optimal asset allocation with value-at-risk constraints [PDF]
In this paper, we consider the optimal asset allocation problems under VaR constraints. It is shown that the separation property holds to a certain extent. The optimal allocation of funds in risky assets is dependent on the distribution of the returns of
Steven Li
core
Dynamic Asset Allocation with Expected Shortfall via Quantum Annealing. [PDF]
Entropy (Basel), 2023 Xu H, Dasgupta S, Pothen A, Banerjee A.
europepmc +1 more source
Advanced Science, EarlyView.A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li +8 more
wiley +1 more source
Advanced Science, EarlyView.This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu +11 more
wiley +1 more source
Application of Robust Statistics to Asset Allocation Models
Revstat Statistical Journal, 2007 Many strategies for asset allocation involve the computation of the expected value and the covariance matrix of the returns of financial instruments.
Roy E. Welsch , Xinfeng Zhou
doaj +1 more source