Results 71 to 80 of about 200,361 (330)

PHYSICIAN ASSISTED DYING: DEFINING THE ETHICALLY AMBIGUOUS [PDF]

open access: yes, 2018
In states where Physician Assisted Dying (PAD) is legal, physicians occasionally receive requests for this form of end-of-life care. Here, I describe the ethically ambiguous sphere and why PAD falls into it.
O'Leary, Chandler
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Introductory Remarks of Panel II: Legal, Medical, and Ethical Considerations for the Future of Physician-Assisted Suicice Symposium: Physician-Assusted Suicide: Legal Rights in Life and Death: Introductory Remarks of Panel II: Legal, Medicial, and Ethical Considerations for the Future of Physician-Assisted Suicide [PDF]

open access: yes, 1996
Once the Supreme Court issues it decision in the cases of Quill v. Vacco1 and Compassion in Dying v. Washington2 regarding the constitutionality of outlawing physician-assisted suicide for competent and terminally ill persons, the tension surrounding ...
Hernandez, Tanya K.
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Conventional and assisted suicide in Switzerland: Insights into a divergent development based on cancer‐associated self‐initiated deaths

open access: yesCancer Medicine, 2023
Background We tested the hypothesis of supporters of assisted dying that assisted suicide (AS) might be able to prevent cases of conventional suicide (CS).
Uwe Güth   +5 more
doaj   +1 more source

Perspectives on assisted dying [PDF]

open access: yesMedicine, Health Care and Philosophy, 2010
There is no shortage of collections or individual papers onassisted dying and other end-of-life issues. They have beena regular feature of ethical evaluation and debate for manyyears. The fact that such papers continue to be published istestimony not only to a continuing awareness of profes-sional and lay concerns, but also to changing circum-stances ...
David, Badcott, Fuat S, Oduncu
openaire   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

A Role for Judges in Assisted Dying [PDF]

open access: yesJournal of Medical Ethics and History of Medicine, 2009
Medically provoked death, whether euthanasia or assisted suicide, is a common issue for discussion in various forums, participants coming from widely differing fields of knowledge, among who are, of course, doctors. Substantial legal differences exist in
Ana Castelló   +2 more
doaj   +1 more source

Dignity and Assisted Dying: What Kant Got Right (and Wrong) [PDF]

open access: yes, 2018
That Kant’s moral thought is invoked by both advocates and opponents of a right to assisted dying attests to both the allure and and the elusiveness of Kant’s moral thought. In particular, the theses that individuals have a right to a ‘death with dignity’
Cholbi, Michael
core  

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