DNA methylation patterns in patients with asthenospermia and oligoasthenospermia [PDF]
BMC GenomicsBackground Spermatogenesis is a highly regulated and complex process in which DNA methylation plays a crucial role. This study aimed to explore the differential methylation profiles in sperm DNA between patients with asthenospermia (AS) and healthy ...
Jingdi Zhang +9 more
doaj +4 more sources
Efficacy of acupuncture in the treatment of asthenospermia in obese men: study protocol for a randomized control trial [PDF]
Frontiers in MedicineBackgroundAsthenospermia is one of the most common causes of male infertility. In recent years, with changes in dietary habits, the number of obese patients with asthenospermia has been increasing, leading to a decline in male fertility.
Hao Wang +7 more
doaj +2 more sources
Enterotypes in asthenospermia patients with obesity
Scientific Reports, 2022 The essence of enterotypes is stratifying the entire human gut microbiome, which modulates the association between diet and disease risk. A study was designed at the Center of Reproductive Medicine, Shengjing Hospital of China Medical University and ...
Jiao Jiao +12 more
doaj +3 more sources
Ultrastructural Aspects of Asthenospermia [PDF]
Journal of Developmental and Physical Disabilities, 1980 In fifty cases of proven asthenospermia semen samples were examined for ultrastructural abnormalities. In 32 of the cases the sperm cells appeared either completely normal, or presented only minor abnormalities. In 15 cases severe teratospermia was observed. In the 3 remaining cases, specific and hitherto undescribed tail abnormalities were detected.
M, Jadot-Van de Casseye +3 more
exaly +3 more sources
Impact of DNA methylation of the human mesoderm-specific transcript (MEST) on male infertility [PDF]
Heliyon, 2023 Male infertility accounts for nearly 40%–50% of all infertile cases. One of the most prevalent disorders detected in infertile men is errors in the MEST differentially methylated region (DMR), which has been correlated with poor sperm indexes. The aim of
Tayebeh Amjadian +3 more
doaj +2 more sources
Correlation of IGF2 levels with sperm quality, inflammation, and DNA damage in infertile patients [PDF]
Asian Journal of AndrologyInsulin-like growth factor 2 (IGF2) is a critical endocrine mediator implicated in male reproductive physiology. To investigate the correlation between IGF2 protein levels and various aspects of male infertility, specifically focusing on sperm quality ...
Jing-Gen Wu +8 more
doaj +2 more sources
Expanding the phenotypic spectrum associated with CFAP43 mutations: a case report of familial male infertility with respiratory manifestations [PDF]
Frontiers in Reproductive HealthAimsMultiple morphological abnormalities of the sperm flagella (MMAF) represents a rare and severe form of male infertility, characterized by defects in sperm flagella.
Fawaz Awad +10 more
doaj +2 more sources
Transcriptome sequencing reveals significant RNA variation in human sperm samples [PDF]
BMC Research NotesDNA transcription and protein translation are non-coupled for life activities after sperm formation, and if the RNA profile of isolated spermatozoa is resolved, it will help men with epigenetic effects on their offspring and male infertility due to RNA ...
Weiming Chen +3 more
doaj +2 more sources
Effectiveness of recombinant follicle-stimulating hormone treatment in patients with oligo-asthenospermia at different levels of DNA fragmentation index: A phase II clinical trial [PDF]
Current Urology. Objective. This study aimed to perform an evaluation of changes in spermogram parameters after follicle-stimulating hormone (FSH) therapy in infertile males having oligo-asthenospermia at different levels of DNA fragmentation index (DFI). Materials and
Salman Soltani +6 more
doaj +2 more sources
The effects of L-carnitine and fructose in improved Ham's F10 on sperm culture in idiopathic severe asthenospermia within 24h. [PDF]
PLoS ONETo study the effects of L-carnitine and fructose on semen parameters of severe asthenospermia patients by sperm culturing in vitro within 24h. We optimized the energy composition and antioxidant substances of sperm culture medium in vitro (based on Ham's
Dehui Chang +12 more
doaj +2 more sources