Results 21 to 30 of about 1,665 (182)

IL-6–174 G/C transversion might decrease male infertility risk: A case-control study [PDF]

International Journal of Reproductive BioMedicine
Background: Genetic predispositions have been identified as important factors in male infertility. Among the many genes related to male reproductive function, interleukin 6 (IL-6) has emerged as a key player.
Tayyebeh Zamani-Badi, Mohammad Karimian, Javad Amini Mahabadi, Atieh Rafatmanesh, Hossein Nikzad   +4 more
doaj   +2 more sources

Seminal per- and polyfluoroalkyl substance exposure and sperm quality impairment: from toxic target to rescue

Environment International
The link between per- and polyfluoroalkyl substances (PFAS) and impaired sperm quality has been disputable, partially attributed to the relatively small sample size and the lack of knowledge on exposure status in the microenvironment of target site. Here,
Lan Shi, Lin Tao, Yating Zong, Chang Gao, Bing Han, Tianrui Gao, Chenghui Huang, Bingjie Liu, Huan Wu, Dongdong Tang, Yajing Liu, Hua Wang, De-Xiang Xu, Yunxia Cao, Yichao Huang, Xiaojin He   +15 more
doaj   +2 more sources

Low-Level Human Epididymis Protein 4 in Seminal Plasma Is an Independent Risk Factor for Poor Semen Liquefaction: A Case Control Study. [PDF]

J Clin Lab Anal
Our work identifies a novel and significant association between low seminal levels of Human Epididymis Protein 4 (HE4) and the clinical condition of poor semen liquefaction, a common cause of male infertility. The findings are statistically robust, clinically relevant, and provide a foundational basis for future research into the mechanism by which HE4
Wang F, Wu J, Gao S, Zheng Z, Wang Z, Gao J.   +5 more
europepmc   +2 more sources

High-Resolution Imaging Reveals Mitochondrial Protein Imbalance in Sperm of Oligoasthenospermic Men. [PDF]

Mol Reprod Dev
ABSTRACT Male infertility accounts for nearly half of global infertility cases and is often linked to poor sperm quality, such as oligospermia, asthenospermia, and teratospermia. Although the exact mechanisms remain unclear, mitochondria, which are critical for ATP production and reactive oxygen species generation during fertilization, are increasingly
Teixeira P, Boguenet M, Pascaretti-Grizon F, Manero F, Plouzennec S, Bouet PE, Reynier P, Chevrollier A, May-Panloup P.   +8 more
europepmc   +2 more sources

Comparing the clinical and singleton neonatal outcomes in male infertility patients with Oligoasthenospermia, OA, or NOA following fresh ICSI-ET using different sources of sperm

Frontiers in Endocrinology, 2023
ObjectiveTo investigate clinical and singleton newborn outcomes in fresh cycles of embryo transfer after intracytoplasmic sperm injection (ICSI-ET) with diverse sperm sources (ejaculate, epididymis, and testis) in patients with Oligoasthenospermia ...
Jianmin Xu, Jianmin Xu, Jianmin Xu, Qingling Yang, Qingling Yang, Qingling Yang, Wenhui Chen, Wenhui Chen, Wenhui Chen, Yuqing Jiang, Yuqing Jiang, Yuqing Jiang, Zhaoyang Shen, Zhaoyang Shen, Zhaoyang Shen, Huan Wang, Huan Wang, Huan Wang, Yingpu Sun, Yingpu Sun, Yingpu Sun   +20 more
doaj   +1 more source

Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus)

BMC Veterinary Research, 2021
Background Fecundity is important for farm blue fox (Vulpes lagopus), who with asthenospermia have be a problem in some of farms in China. A key symptom of asthenospermia is decreased sperm motility.
Ping Wu, Tao-lin Liu, Ling-ling Li, Zhi-ping Liu, Li-hong Tian, Zhi-jun Hou   +5 more
doaj   +1 more source

Expression changes of superoxide dismutase 2 and peroxiredoxin 6 in asthenospermia and their correlation with sperm motility

Di-san junyi daxue xuebao, 2021
Objective To explore the damaging effects of reactive oxygen species (ROS) on spermatozoa, and investigate the expression changes of superoxide dismutase 2 (SOD2) and peroxiredoxin 6 (PRDX6) in spermatozoa of asthenospermia patients, so as to analyze ...
YANG Zihan, YANG Zihan, HAO Xiaoling, HAO Xiaoling, WANG Hong, HUANG Run, MENG Jiangping   +6 more
doaj   +1 more source

Effect of Propolis Oral Supplements on Sperm Parameters and Oxidative Stress Indicator in Idiopathic Infertile Men: A double-blind Randomized Clinical Trial [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2018
Introduction: Decrease in sperm motility and increase in oxidative stress levels are of the main causes of male infertility. Since the fertility has high value in most cultures, this study was performed with aim to investigate the effect of propolis ...
Maryam Javadi, Fereshteh Gholaminejad, Hossein Khadem Haghighian, Ali Akbar Karami, Fatemeh Alizadeh   +4 more
doaj   +1 more source

Seminal Plasma Exosomal miRNA Profiling Reveals hsa-miR-7-5p as a Key Regulator of Sperm Motility in Asthenozoospermia. [PDF]

Andrology
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhu ZJ, Cui ML, Yuan WJ, Zhang JN, Zhang S, Yao XQ, Li RQ, Li JF, Li EZ.   +8 more
europepmc   +2 more sources

CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module [PDF]

, 2020
Contains fulltext : 229376.pdf (Publisher’s version ) (Open Access)Axonemal dynein ATPases direct ciliary and flagellar beating via adenosine triphosphate (ATP) hydrolysis.
Ueffing, Marius, Olbrich, H., Katsanis, Nicholas, Ikawa, Y., Kaiser, Thomas, Memari, Yasin, Omran, H., Perles, Z., Klinkenbusch, Judith A, Höben, Inga M, Ikawa, Yayoi, Hjeij, R., Bartscherer, K., Nöthe-Menchen, Tabea, Minegishi, K., Dzeja, P.P., Boldt, K., Olbrich, Heike, Dzeja, Petras P, Amirav, I., Hamada, Hiroshi, Nöthe-Menchen, T., Mizuno, K., Stumme, Friederike, Hjeij, Rim, Loges, N.T., Wallmeier, J., Takaoka, Katsuyoshi, Aviram, Micha, Pang, Y.P., Shiratori, H., Gützlaff, Jana, Omran, Heymut, Elpeleg, O., Raidt, J., Strünker, Timo, Roepman, R., Klinkenbusch, J.A., Aviram, M., Wallmeier, Julia, Perles, Zeev, Roepman, Ronald, Mussaffi, H., Letteboer, Stef J, Loges, Niki T, Ta-Shma, Asaf, Bracht, Diana C, Große-Onnebrink, J., Dworniczak, B., Dougherty, G.W., Horn, Nicola, Twan, W.K., Shiratori, Hidetaka, Takaoka, K., Große-Onnebrink, Jörg, Pang, Yuan-Ping, Letteboer, S.J.F., Praveen, Kavita, Mizuno, Katsutoshi, Rabert, Franziska, Twan, Wang Kyaw, Minegishi, Katsura, Stumme, F., Gützlaff, J., Katsanis, N., Ueffing, M., Dougherty, Gerard W, Ide, T., Davis, E.E., Cindrić, Sandra, Cindrić, S., Young, S., Höben, I.M., Hamada, H., Dworniczak, Bernd, Elpeleg, Orly, Werner, C., Rabert, F., Pennekamp, P., Junger, K., Junger, Katrin, Ta-Shma, A., Bartscherer, Kerstin, Biebach, L., Pennekamp, Petra, Biebach, Luisa, Horn, N., Aprea, Isabella, Boldt, Karsten, Werner, Claudius, Young, Samuel, Bracht, D.C., Raidt, Johanna, Mussaffi, Huda, Kaiser, T., Aprea, I., Strünker, T., Praveen, K., Ide, Takahiro, Davis, Erica E, Amirav, Israel, Memari, Y.   +101 more
core   +3 more sources